scholarly journals Automating Quality Measures for Heart Failure Using Natural Language Processing: A Descriptive Study in the Department of Veterans Affairs (Preprint)

2017 ◽  
Author(s):  
Jennifer Hornung Garvin ◽  
Youngjun Kim ◽  
Glenn Temple Gobbel ◽  
Michael E Matheny ◽  
Andrew Redd ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Left Ventricular ◽  
Veterans Affairs ◽  
Quality Measure ◽  
Left Ventricular Ejection ◽  
Department Of Veterans Affairs

BACKGROUND We developed an accurate, stakeholder-informed, automated, natural language processing (NLP) system to measure the quality of heart failure (HF) inpatient care, and explored the potential for adoption of this system within an integrated health care system. OBJECTIVE To accurately automate a United States Department of Veterans Affairs (VA) quality measure for inpatients with HF. METHODS We automated the HF quality measure Congestive Heart Failure Inpatient Measure 19 (CHI19) that identifies whether a given patient has left ventricular ejection fraction (LVEF) <40%, and if so, whether an angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker was prescribed at discharge if there were no contraindications. We used documents from 1083 unique inpatients from eight VA medical centers to develop a reference standard (RS) to train (n=314) and test (n=769) the Congestive Heart Failure Information Extraction Framework (CHIEF). We also conducted semi-structured interviews (n=15) for stakeholder feedback on implementation of the CHIEF. RESULTS The CHIEF classified each hospitalization in the test set with a sensitivity (SN) of 98.9% and positive predictive value of 98.7%, compared with an RS and SN of 98.5% for available External Peer Review Program assessments. Of the 1083 patients available for the NLP system, the CHIEF evaluated and classified 100% of cases. Stakeholders identified potential implementation facilitators and clinical uses of the CHIEF. CONCLUSIONS The CHIEF provided complete data for all patients in the cohort and could potentially improve the efficiency, timeliness, and utility of HF quality measurements.

An Evolving Ecosystem for Natural Language Processing in Department of Veterans Affairs

2017 ◽  
Vol 41 (2) ◽  
Author(s):  
Jennifer H. Garvin ◽  
Megha Kalsy ◽  
Cynthia Brandt ◽  
Stephen L. Luther ◽  
Guy Divita ◽  
...  
Keyword(s):  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Veterans Affairs ◽  
Department Of Veterans Affairs

Ascertainment of Veterans With Metastatic Prostate Cancer in Electronic Health Records: Demonstrating the Case for Natural Language Processing

2021 ◽  
pp. 1005-1014
Author(s):  
Patrick R. Alba ◽  
Anthony Gao ◽  
Kyung Min Lee ◽  
Tori Anglin-Foote ◽  
Brian Robison ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Metastatic Prostate Cancer ◽  
Cancer Registries ◽  
Veterans Affairs ◽  
Department Of Veterans Affairs ◽  
Cancer Registry Data ◽  
Number Of Patients

PURPOSE Prostate cancer (PCa) is among the leading causes of cancer deaths. While localized PCa has a 5-year survival rate approaching 100%, this rate drops to 31% for metastatic prostate cancer (mPCa). Thus, timely identification of mPCa is a crucial step toward measuring and improving access to innovations that reduce PCa mortality. Yet, methods to identify patients diagnosed with mPCa remain elusive. Cancer registries provide detailed data at diagnosis but are not updated throughout treatment. This study reports on the development and validation of a natural language processing (NLP) algorithm deployed on oncology, urology, and radiology clinical notes to identify patients with a diagnosis or history of mPCa in the Department of Veterans Affairs. PATIENTS AND METHODS Using a broad set of diagnosis and histology codes, the Veterans Affairs Corporate Data Warehouse was queried to identify all Veterans with PCa. An NLP algorithm was developed to identify patients with any history or progression of mPCa. The NLP algorithm was prototyped and developed iteratively using patient notes, grouped into development, training, and validation subsets. RESULTS A total of 1,144,610 Veterans were diagnosed with PCa between January 2000 and October 2020, among which 76,082 (6.6%) were identified by NLP as having mPCa at some point during their care. The NLP system performed with a specificity of 0.979 and sensitivity of 0.919. CONCLUSION Clinical documentation of mPCa is highly reliable. NLP can be leveraged to improve PCa data. When compared to other methods, NLP identified a significantly greater number of patients. NLP can be used to augment cancer registry data, facilitate research inquiries, and identify patients who may benefit from innovations in mPCa treatment.

scholarly journals Identify Patients with Congestive Heart Failure through Analyzing Free-Text Clinical Notes

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Margot Yann ◽  
Therese Stukel ◽  
Liisa Jaakkimainen ◽  
Karen Tu
Keyword(s):  
Heart Failure ◽  
Primary Care ◽  
Congestive Heart Failure ◽  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Substantial Reduction ◽  
Free Text ◽  
Test Dataset ◽  
Clinical Notes

IntroductionA number of challenges exist in analyzing unstructured free text data in electronic medical records (EMRs). EMR text are difficult to represent and model due to their high dimensionality, heterogeneity, sparsity, incompleteness, random errors and the presence of noise. Objectives and ApproachStandard Natural Language Processing (NLP) tools make errors when applied to clinical notes due to physician use of unconventional language, involving polysemy, abbreviations, ambiguity, misspelling, variations, and negation. This paper presents a novel NLP framework, “Clinical Learning On Natural Expression” (CLONE), to automatically learn from a large primary care EMR database, analyzing free text clinical notes from primary care practices. CLONE’s predictive clinical models using text mining and neural network approach to extract features to identify patterns. To demonstrate effectiveness, we evaluate CLONE’s ability in a case study to identify patients with a specific chronic condition: congestive heart failure (CHF). ResultsA random selected sample of 7500 patients from Electronic Medical Record Administrative data Linked Database (EMRALD) is used. In this dataset, each patient’s medical chart includes a reference standard, manually reviewed by medical practitioners. Prevalence of CHF is approximately 2%. The low prevalence leads to another challenging problem in machine learning: imbalanced datasets. After pre-processing, we build deep learning models to represent and extract important medical information from free text to identify CHF patients through analyzing patient charts. We evaluated the effectiveness of CLONE by comparing the predicted labels with the standard references on a holdout test dataset. Comparing it with a number of alternative algorithms, we improve the overall accuracy to over 90% on a test dataset. Conclusion/ImplicationsAs the role of NLP in EMR data expands, the CLONE natural language processing framework can lead to substantial reduction in manual processing, while improving predictive accuracy.

Identifying Heart Failure Symptoms and Poor Self-Management in Home Healthcare: A Natural Language Processing Study

2021 ◽  
Author(s):  
Sena Chae ◽  
Jiyoun Song ◽  
Marietta Ojo ◽  
Maxim Topaz
Keyword(s):  
Heart Failure ◽  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Symptom Management ◽  
Home Healthcare ◽  
Self Management ◽  
Clinical Notes ◽  
Patients With Heart Failure

The goal of this natural language processing (NLP) study was to identify patients in home healthcare with heart failure symptoms and poor self-management (SM). The preliminary lists of symptoms and poor SM status were identified, NLP algorithms were used to refine the lists, and NLP performance was evaluated using 2.3 million home healthcare clinical notes. The overall precision to identify patients with heart failure symptoms and poor SM status was 0.86. The feasibility of methods was demonstrated to identify patients with heart failure symptoms and poor SM documented in home healthcare notes. This study facilitates utilizing key symptom information and patients’ SM status from unstructured data in electronic health records. The results of this study can be applied to better individualize symptom management to support heart failure patients’ quality-of-life.

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