scholarly journals Effect on Nitrogen Balance, Thermogenesis, Body Composition, Satiety, and Circulating Branched Chain Amino Acid Levels up to One Year after Surgery: Protocol of a Randomized Controlled Trial on Dietary Protein During Surgical Weight Loss

2016 ◽  
Vol 5 (4) ◽  
pp. e220 ◽  
Author(s):  
Violeta Moizé ◽  
Xavier Pi-Sunyer ◽  
Josep Vidal ◽  
Patricia Miner ◽  
Yves Boirie ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Body Composition ◽  
Dietary Protein ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Branched Chain Amino Acid ◽  
Amino Acid Levels ◽  
Branched Chain ◽  
One Year

scholarly journals A randomized controlled trial: branched-chain amino acid levels and glucose metabolism in patients with obesity and sleep apnea

2017 ◽  
Vol 26 (6) ◽  
pp. 773-781 ◽  
Author(s):  
Antonia Barceló ◽  
Daniel Morell-Garcia ◽  
Neus Salord ◽  
Cristina Esquinas ◽  
Gerardo Pérez ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Amino Acid ◽  
Sleep Apnea ◽  
Glucose Metabolism ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Branched Chain Amino Acid ◽  
Amino Acid Levels ◽  
Branched Chain

One year weight loss in the TRAMOMTANA study. A randomized controlled trial

2013 ◽  
Vol 79 (6) ◽  
pp. 791-799 ◽  
Author(s):  
Juan Jesús Tur ◽  
Antonio Jorge Escudero ◽  
María Micaela Alos ◽  
Ramón Salinas ◽  
Emma Terés ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
One Year

scholarly journals Rationale and Protocol for a Randomized Controlled Trial Comparing Fast versus Slow Weight Loss in Postmenopausal Women with Obesity—The TEMPO Diet Trial

Healthcare ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 85 ◽  
Author(s):  
Radhika Seimon ◽  
Alice Gibson ◽  
Claudia Harper ◽  
Shelley Keating ◽  
Nathan Johnson ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Body Composition ◽  
Eating Disorder ◽  
Controlled Trial ◽  
Energy Restriction ◽  
Cardiometabolic Health ◽  
Meal Replacement ◽  
Randomized Controlled ◽  
Eating Disorder Behaviors

Very low energy diets (VLEDs), commonly achieved by replacing all food with meal replacement products and which result in fast weight loss, are the most effective dietary obesity treatment available. VLEDs are also cheaper to administer than conventional, food-based diets, which result in slow weight loss. Despite being effective and affordable, these diets are underutilized by healthcare professionals, possibly due to concerns about potential adverse effects on body composition and eating disorder behaviors. This paper describes the rationale and detailed protocol for the TEMPO Diet Trial (Type of Energy Manipulation for Promoting optimal metabolic health and body composition in Obesity), in a randomized controlled trial comparing the long-term (3-year) effects of fast versus slow weight loss. One hundred and one post-menopausal women aged 45–65 years with a body mass index of 30–40 kg/m2 were randomized to either: (1) 16 weeks of fast weight loss, achieved by a total meal replacement diet, followed by slow weight loss (as for the SLOW intervention) for the remaining time up until 52 weeks (“FAST” intervention), or (2) 52 weeks of slow weight loss, achieved by a conventional, food-based diet (“SLOW” intervention). Parameters of body composition, cardiometabolic health, eating disorder behaviors and psychology, and adaptive responses to energy restriction were measured throughout the 3-year trial.

scholarly journals Moms in motion: weight loss intervention for postpartum mothers after gestational diabetes: a randomized controlled trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Briana J. Stith ◽  
Samantha M. Buls ◽  
Sarah A. Keim ◽  
Stephen F. Thung ◽  
Mark A. Klebanoff ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Body Composition ◽  
Energy Expenditure ◽  
Gestational Diabetes ◽  
Controlled Trial ◽  
Daily Activities ◽  
Randomized Controlled ◽  
Postpartum Weight

Abstract Background Up to 50 % of women with gestational diabetes mellitus (GDM) will receive a diagnosis of type 2 diabetes mellitus (T2DM) within a decade after pregnancy. While excess postpartum weight retention exacerbates T2DM risk, lifestyle changes and behavior modifications can promote healthy postpartum weight loss and contribute to T2DM prevention efforts. However, some women have difficulty prioritizing self-care during this life stage. Efficacious interventions that women can balance with motherhood to reduce T2DM risk remain a goal. The objective of the Moms in Motion study is to evaluate the efficacy of a simple, novel, activity-boosting intervention using ankle weights worn with daily activities during a 6-month postpartum intervention among women with GDM. We hypothesize that women randomized to the 6-month intensity-modifying intervention will (1) demonstrate greater weight loss and (2) greater improvement in body composition and biomarker profile versus controls. Methods This study will be a parallel two-arm randomized controlled trial (n = 160). Women will be allocated 1:1 to an ankle weight intervention group or a standard-of-care control group. The intervention uses ankle weights (1.1 kg) worn on each ankle during routine daily activities (e.g., cleaning, childcare). Primary outcomes include pre- and post-assessments of weight from Visit 2 to Visit 3. Secondary outcomes include body composition, glycemia (2-h, 75 g oral glucose tolerance test), and fasting insulin. Exploratory outcomes include energy expenditure, diet, and psychosocial well-being. Discussion Beyond the expected significance of this study in its direct health impacts from weight loss, it will contribute to exploring (1) the mechanism(s) by which the intervention is successful (mediating effects of energy expenditure and diet on weight loss) and (2) the effects of the intervention on body composition and biomarkers associated with insulin resistance and metabolic health. Additionally, we expect the findings to be meaningful regarding the intervention’s effectiveness on engaging women with GDM in the postpartum period to reduce T2DM risk. Trial registration The ClinicalTrials.gov Identifier, is NCT03664089. The trial registration date is September 10, 2018. The trial sponsor is Dr. Sarah A. Keim.

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