Corrigendum notice: Protective Effect of Interval Exercise Training with Different Intensity and Alpha-Lipoic Acid Supplement on Nav1.3 Protein in Soleus Muscle of Diabetic Rats

The article's abstract is not available.

PSX-A-15 Late-Breaking: Use of a rumen-protected fatty acid supplement on growth performance in feedlot heifers

The objective of this experiment was to evaluate the of use different doses of a rumen protected fatty acid supplement in feedlot heifers. Seventy-two (cross bread) heifers were blocked by body weight and animals within each block were randomly allotted to a pen. Each pen had 4 heifers, and there were 6 pens per treatment. All animals were fed a basal diet of 14% corn silage, 73% dry rolled corn, 10% cracked soybeans, 1% urea, and 2% mineral vitamin mix for 83 days. Each treatment received different dose of a rumen-protected fatty acid supplement (RPFA), which contained 40% flaxseed oil, 55% treated soy lecithin, and 5% dextrose; processed using the procedure described in the patent (pending: US 2020/0197346 A1). Treatments were T1: 125 g RPFA; T2: 250 g of RPFA, and T3: 375 g of RPFA. Treatments were daily top dressed. Heifers were weighted on days 0, 50, and 83. Longissimus dorsi muscle (LMA) and back fat (BF) at the 13 rib were measured using ultrasound day 0 and 83, before the animals were sent to slaughter. Dry matter offered per day and refusal collected twice a week were used to estimate dry matter intake (DMI). Data were analyzed as a randomized complete block design, with treatment as a fixed variable and block as a random variable. Means were separated using a polynomial contrast. There were no differences (P ≥ 0.16; Table 1) on final body weight, average daily gain (ADG), DMI, gain to DMI ratio, or dressing percentage. There where quadratic tendencies (P ≤ 0.1; Table 1) for hot carcass weight (HCW), LMA, and BF. Based in the results from the current experiment, feeding 100 g of flaxseed oil (250 g of RPFA) improves HCW and LMA but also BF, without affecting growth and DMI.

Preconception Dietary Folate Intake and Risk of Spontaneous Abortion

Objectives Previous studies suggest a beneficial effect of supplemental folic acid use and dietary folate intake on fertility, while results for fetal loss are conflicting. Most previous research on fetal loss focused on folic acid supplement use. We therefore, investigated the association between dietary folate intake and spontaneous abortion (SAB) in a Danish preconception cohort of couples trying to conceive. Methods We recruited couples who were trying to conceive and did not receive fertility treatment. Pregnancies were ascertained through bimonthly follow-up questionnaires completed up to 12 months after study entry. SABs were identified by self-report on the follow-up questionnaires and through the Danish National Patient Registry. Dietary folate intake at study entry was estimated using a validated food frequency questionnaire (FFQ). Folate intake was adjusted for total energy intake using the residual method and categorized as < 250,250–399 and > = 400µg/day. We used Cox proportional hazards regression models with gestational weeks as time scale to compute hazard ratios (HRs) and 95% confidence intervals (CIs) for SAB, adjusting for age, partner's age, educational attainment, smoking status, anthropometry, physical activity, alcohol intake, folic acid supplement use, time-to-pregnancy, gravidity and parity. In sensitivity analyses, we stratified by folic acid supplement use, body mass index (BMI) and alcohol intake. Results Of the 2,957 women who became pregnant within 12 months of study entry and completed the FFQ, we identified 432 SABs. HRs for an SAB among women who consumed 250–399 and >= 400 µg/day of dietary folate compared with <250 µg/day were 0.83 (95% CI: 0.53; 1.29) and 0.87 (95% CI: 0.54; 1.39), respectively. Comparing intake > = 400 with <250 µg/day, the association was stronger when the analysis was restricted to folic acid supplement users, 0.74 (95% CI: 0.39; 1.40), to women with a BMI >= 25, 0.67 (95% CI: 0.31; 1.43), and to a reported alcohol intake >4 drinks/week, 0.66 (95% CI: 0.16; 2.66). Conclusions Our study may suggest that high dietary folate intake among folic acid supplement users is associated with a lower risk of SAB, although our estimates are imprecise. Funding Sources National Institute of Child Health and Human Development.

Effects of Two Plant-Based Dietary Supplements on Cardiovascular Health and Low-Grade Inflammation in the Elderly: Study Protocol for a Randomised Controlled Trial

Objectives To assess whether the long-term separate ingestions of an encapsulated juice powder concentrate and a plant-based omega fatty acid supplement, or a combined ingestion of the two, can affect biomarkers of cardiovascular health, low-grade inflammation and indicators of aging in the elderly. Methods This is a randomised, controlled, open-labelled, parallel-grouped clinical trial, consisting of 4 arms. One hundred and twelve, overweight and obese (BMI 25–35 kg/m2) subjects, aged 60 to 80 years will be recruited and randomly allocated to: i) control group; ii) Fruit, Vegetable and Berry (FVB) group, where participants have to ingest a fruit, vegetable and berry supplement (Juice Plus+® capsules); iii) Omega group, where participants have to ingest a plant-based fatty acid supplement (Juice Plus+® Omega Blend); and iv) Fruit, Vegetable, Berry and Omega (FVBO) group, where participants have to ingest the fruit, vegetable and berry supplement, together with the plant-based fatty acid supplement. Participants in all groups will continue their habitual diet and lifestyle. Those allocated to one of the three intervention groups, will be asked to ingest the supplements for a total duration of two years. Participants will be assessed at baseline and at follow-up visits at 6, 12, 18 and 24 months. Primary outcomes include markers of cardiovascular health and low-grade inflammation. Secondary outcomes include selected indicators of aging, cognitive function, immunity and quality of life. Finally, plasma levels of vitamins, carotenoids and fatty acids will also be assessed. Results N/A Conclusions This study will provide evidence whether long-term, plant-based dietary supplementation can support cardiovascular health, anti-inflammatory processes, immunity and nutritional status in aging. Funding Sources The Juice Plus + Science Institute received funding by The Juice Plus+® Company for this project.