Triple Arterial Phase Dynamic MRI with Sensitivity Encoding for Hypervascular Hepatocellular Carcinoma: Comparison of the Diagnostic Accuracy Among the Early, Middle, Late, and Whole Triple Arterial Phase Imaging

2005 ◽  
Vol 184 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Kensaku Mori ◽  
Hiroshi Yoshioka ◽  
Nobuyuki Takahashi ◽  
Masayuki Yamaguchi ◽  
Teruko Ueno ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Diagnostic Accuracy ◽  
Dynamic Mri ◽  
Arterial Phase ◽  
Phase Imaging ◽  
Phase Dynamic ◽  
Sensitivity Encoding

scholarly journals Double arterial phase dynamic MRI with sensitivity encoding (SENSE) for hypervascular hepatocellular carcinomas

2002 ◽  
Vol 16 (3) ◽  
pp. 259-266 ◽  
Author(s):  
Hiroshi Yoshioka ◽  
Nobuyuki Takahashi ◽  
Masayuki Yamaguchi ◽  
Douqiang Lou ◽  
Yukihisa Saida ◽  
...  
Keyword(s):  
Dynamic Mri ◽  
Arterial Phase ◽  
Phase Dynamic ◽  
Sensitivity Encoding ◽  
Hepatocellular Carcinomas

Differentiation between hepatocellular carcinoma and intrahepatic cholangiocarcinoma using contrast-enhanced ultrasound: A systematic review and meta-analysis

2021 ◽  
pp. 1-17
Author(s):  
Yanling Chen ◽  
Wenping Wang
Keyword(s):  
Hepatocellular Carcinoma ◽  
Diagnostic Accuracy ◽  
Publication Bias ◽  
Likelihood Ratio ◽  
Intrahepatic Cholangiocarcinoma ◽  
Cochrane Library ◽  
Arterial Phase ◽  
Contrast Enhanced Ultrasound ◽  
Diagnostic Ability ◽  
Contrast Enhanced

AIM: To explore the diagnostic ability of contrast-enhanced ultrasound (CEUS) in distinguishing intrahepatic cholangiocarcinoma (ICC) from hepatocellular carcinoma (HCC). MATERIALS AND METHODS: PubMed, EMBASE, Cochrane Library, and Web of Science were systematically searched for studies reporting the diagnostic accuracy of CEUS in differentiating ICC from HCC. The diagnostic ability of CEUS was assessed based on the pooled sensitivity, specificity, diagnostic odds ratio (DOR), positive likelihood ratio (PLR), negative likelihood ratio (NLR) and area under the curve (AUC) with 95% confidence intervals (CIs). The methodologic quality was assessed by the QUADAS-2 tool. Subgroup analyses, meta-regression and investigation of publication bias were performed to identify the source of heterogeneity. RESULTS: A total of eight studies were included, consisting of 1,116 patients with HCC and 529 with ICC. The general diagnostic performance of CEUS in distinguishing ICC and HCC were as follows: pooled sensitivity, 0.92 (95% CI: 0.84–0.96); pooled specificity, 0.87 (95% CI: 0.79–0.92); pooled PLR, 7.1 (95% CI: 4.1–12.0); pooled NLR, 0.09 (95% CI: 0.05–0.19); pooled DOR, 76 (95% CI: 26–220) and AUC, 0.95(95% CI: 0.93–0.97). Different liver background may be a potential factor that influenced the diagnostic accuracy of CEUS according to the subgroup analysis, with the pooled DOR of 89.67 in the mixed liver background group and 46.87 in the cirrhosis group, respectively. Six informative CEUS features that may help differentiate HCC from ICC were extracted. The three CEUS features favoring HCC were arterial phase hyperenhancement(APHE), mild washout and late washout (>60s); the three CEUS favoring ICC were arterial rim enhancement, marked washout and early washout(<60s). No potential publication bias was observed. CONCLUSION: CEUS showed great diagnostic ability in differentiating ICC from HCC, which may be promising for noninvasive evaluation of these diseases.

Hypervascular Hepatocellular Carcinoma: Can Double Arterial Phase Imaging with Multidetector CT Improve Tumor Depiction in the Cirrhotic Liver?

2002 ◽  
Vol 179 (3) ◽  
pp. 751-758 ◽  
Author(s):  
Tomoaki Ichikawa ◽  
Takatoshi Kitamura ◽  
Hiroto Nakajima ◽  
Hironobu Sou ◽  
Tatsuaki Tsukamoto ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Multidetector Ct ◽  
Cirrhotic Liver ◽  
Arterial Phase ◽  
Phase Imaging

scholarly journals Diagnostic evaluation and ablation treatments assessment in hepatocellular carcinoma

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Vincenza Granata ◽  
Roberta Grassi ◽  
Roberta Fusco ◽  
Andrea Belli ◽  
Carmen Cutolo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
English Language ◽  
Gadobenate Dimeglumine ◽  
Diagnostic Evaluation ◽  
Mri Contrast Agent ◽  
Diagnostic Tools ◽  
Arterial Phase ◽  
Hepatobiliary Phase ◽  
Phase Imaging ◽  
Ablative Therapies

AbstractThis article provides an overview of diagnostic evaluation and ablation treatment assessment in Hepatocellular Carcinoma (HCC). Only studies, in the English language from January 2010 to January 202, evaluating the diagnostic tools and assessment of ablative therapies in HCC patients were included. We found 173 clinical studies that satisfied the inclusion criteria.HCC may be noninvasively diagnosed by imaging findings. Multiphase contrast-enhanced imaging is necessary to assess HCC. Intravenous extracellular contrast agents are used for CT, while the agents used for MRI may be extracellular or hepatobiliary. Both gadoxetate disodium and gadobenate dimeglumine may be used in hepatobiliary phase imaging. For treatment-naive patients undergoing CT, unenhanced imaging is optional; however, it is required in the post treatment setting for CT and all MRI studies. Late arterial phase is strongly preferred over early arterial phase. The choice of modality (CT, US/CEUS or MRI) and MRI contrast agent (extracelllar or hepatobiliary) depends on patient, institutional, and regional factors. MRI allows to link morfological and functional data in the HCC evaluation. Also, Radiomics is an emerging field in the assessment of HCC patients.Postablation imaging is necessary to assess the treatment results, to monitor evolution of the ablated tissue over time, and to evaluate for complications. Post- thermal treatments, imaging should be performed at regularly scheduled intervals to assess treatment response and to evaluate for new lesions and potential complications.

Non-invasive diagnosis of hepatocellular carcinoma ⩽2cm in cirrhosis. Diagnostic accuracy assessing fat, capsule and signal intensity at dynamic MRI

2012 ◽  
Vol 56 (6) ◽  
pp. 1317-1323 ◽  
Author(s):  
Jordi Rimola ◽  
Alejandro Forner ◽  
Silvia Tremosini ◽  
Maria Reig ◽  
Ramón Vilana ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Diagnostic Accuracy ◽  
Signal Intensity ◽  
Dynamic Mri ◽  
Non Invasive
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