Where’s Waldo: Revisiting the Administrative Novel

Public Voices ◽  
2017 ◽  
Vol 15 (1) ◽  
pp. 1
Author(s):  
George Connor
Keyword(s):  
Organization And Administration ◽  
Player Piano ◽  
Simple Observation ◽  
Novel Approach ◽  
Contemporary Work

In 1968 Dwight Waldo published The Novelist on Organization and Administration: An Inquiry into the Relationships Between the Two Worlds.  His very simple observation was that “one can learn much about administration from novels” (1968, 4). After thirty years, it may be a time to re-examine both the literary and academic side of Waldo’s novel approach. The article offers Kurt Vonnegut’s Player Piano and David Foster Wallace’s The Pale King, one classic and one contemporary work, as vehicles for revisiting Waldo’s pedagogy and reestablishing the linkage between administration and administrative novels.

scholarly journals Finding the "odd one out": Memory color effects and the logic of appearance

2018 ◽  
Author(s):  
JJ Valenti ◽  
Chaz Firestone
Keyword(s):  
Prior Knowledge ◽  
Sensory Processing ◽  
Visual Processing ◽  
Color Perception ◽  
Object Perception ◽  
Visual Appearance ◽  
General Utility ◽  
Novel Approach ◽  
Contemporary Work ◽  
Per Se

Can what we know change what we see? A line of research stretching back nearly a century suggests that knowing an object’s canonical color can alter its visual appearance, such that objectively gray bananas appear to be tinged with yellow, and objectively orange hearts appear redder than they really are. Such “memory color” effects have constituted the strongest and most complete evidence that basic sensory processing can be penetrated by higher-level knowledge, and have contributed to theories of object perception in psychology, neuroscience, and even philosophy. Are such phenomena truly perceptual? Or could they instead reflect shifts in judgments and responses without altering online color perception? Here, we take a novel approach to this question by exploiting a “logic” that is inherent in visual processing but that higher-level cognition often cannot follow. In four experiments spanning both classical and contemporary work, we exhaust the predictions of memory color theories by exploring scenarios where memory color accounts make tortuous hypotheses that would be difficult for subjects to grasp, but that should be easily accommodated by visual processing. We show that such conditions eliminate or even reverse memory color effects in ways unaccounted-for by their underlying theories — especially in a novel “odd one out” paradigm that may help distinguish visual appearance from higher-level judgment in a powerful and general way. We suggest that prior knowledge can influence color judgments in real and robust ways, but that such influences may not truly reflect changes in visual appearance per se. We further discuss the general utility of this approach for isolating perception from judgment, both for memory color effects and beyond.

Employment Quality: An Overlooked Determinant of Workers’ Health and Well-being?

2019 ◽  
Vol 63 (6) ◽  
pp. 619-623 ◽  
Author(s):  
Christophe Vanroelen
Keyword(s):  
Health And Safety ◽  
Economic Restructuring ◽  
Well Being ◽  
Market Theory ◽  
Psychosocial Risks ◽  
Novel Approach ◽  
Relative Neglect ◽  
Health Related ◽  
Contemporary Work ◽  
Employment Quality

Abstract In the past four decades, high-income countries have seen a thorough socio-economic restructuring with important implications for the jobs of many workers, including health- and safety-related aspects. Much attention has been paid to psychosocial risks related to intrinsic features of contemporary work tasks, while the occupational health and safety consequences of ‘new’ conditions and relations of employment have remained neglected. This relative neglect is unjustified given the disrupting nature of many contemporary forms of employment. In this commentary, I introduce the concept of ‘employment quality’ as a novel approach towards measuring employment-related OHS risks. Employment quality involves a ‘typological approach’ towards employment arrangements, identifying five employment types in European labour markets, showing a distinct profile in terms of health-related employment characteristics. Moreover, these types align with segmented labour market theory, have a clear socio-economic profile, and show strong associations with workers’ self-reported health.

Copper-dependent ATP7B up-regulation drives the resistance of TMEM16A-overexpressing head-and-neck cancer models to platinum toxicity

2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov
Keyword(s):  
Oxidative Stress ◽  
Head And Neck ◽  
Transcriptional Activation ◽  
Platinum Resistance ◽  
Mrna Levels ◽  
Strong Positive Correlation ◽  
Platinum Compounds ◽  
Copper Chelation ◽  
Novel Approach ◽  
Cancer Models

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.

Collecting Words: A Clinical Example of a Morphology-Focused Orthographic Intervention

2020 ◽  
Vol 51 (3) ◽  
pp. 544-560 ◽  
Author(s):  
Kimberly A. Murphy ◽  
Emily A. Diehm
Keyword(s):  
Written Language ◽  
Morphological Knowledge ◽  
English Orthography ◽  
Word Level ◽  
Novel Approach ◽  
Language Pathology ◽  
The One ◽  
Critical Intervention ◽  
Reading And Spelling ◽  
Reading And Spelling Difficulties

Purpose Morphological interventions promote gains in morphological knowledge and in other oral and written language skills (e.g., phonological awareness, vocabulary, reading, and spelling), yet we have a limited understanding of critical intervention features. In this clinical focus article, we describe a relatively novel approach to teaching morphology that considers its role as the key organizing principle of English orthography. We also present a clinical example of such an intervention delivered during a summer camp at a university speech and hearing clinic. Method Graduate speech-language pathology students provided a 6-week morphology-focused orthographic intervention to children in first through fourth grade ( n = 10) who demonstrated word-level reading and spelling difficulties. The intervention focused children's attention on morphological families, teaching how morphology is interrelated with phonology and etymology in English orthography. Results Comparing pre- and posttest scores, children demonstrated improvement in reading and/or spelling abilities, with the largest gains observed in spelling affixes within polymorphemic words. Children and their caregivers reacted positively to the intervention. Therefore, data from the camp offer preliminary support for teaching morphology within the context of written words, and the intervention appears to be a feasible approach for simultaneously increasing morphological knowledge, reading, and spelling. Conclusion Children with word-level reading and spelling difficulties may benefit from a morphology-focused orthographic intervention, such as the one described here. Research on the approach is warranted, and clinicians are encouraged to explore its possible effectiveness in their practice. Supplemental Material https://doi.org/10.23641/asha.12290687

Abstract #709: E-Consults: A Novel Approach to Increase Access to Subspecialty Care in Endocrinology

2015 ◽  
Vol 21 ◽  
pp. 128
Author(s):  
Kaniksha Desai ◽  
Halis Akturk ◽  
Ana Maria Chindris ◽  
Shon Meek ◽  
Robert Smallridge ◽  
...  
Keyword(s):  
Novel Approach
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