scholarly journals ECHOCARDIOGRAPHIC ASSESSMENT OF HYPERTENSIVE CHANGES IN ELDERLY PATIENTS OF ISOLATED SYSTOLIC HYPERTENSION WITH SPECIAL REFERENCE TO CARDIOVASCULAR COMPLICATIONS

2021 ◽  
pp. 46-51
Author(s):  
BIJAYA KUMAR BEHERA ◽  
RAKESH MOHANTY ◽  
SUKANTA KUMAR JENA ◽  
SUSANTA SEKHAR BEHERA
Keyword(s):  
Elderly Patients ◽  
Systolic Hypertension ◽  
General Medicine ◽  
Cardiovascular Complications ◽  
Left Ventricular ◽  
Antihypertensive Drug Therapy ◽  
Diastolic Filling ◽  
Isolated Systolic Hypertension ◽  
Cross Sectional ◽  
Reduced Ejection Fraction

Objective: The objective of the study was to assess the echocardiographic changes and cardiovascular complications in patients with isolated systolic hypertension (ISH). Methods: This was an observational cross-sectional study done in the Departments of General Medicine, Cardiology, and Radiodiagnosis of MKCG Medical College and Hospital, Berhampur, Odisha, India. Seventy patients above the age of 65 years with systolic blood pressure (BP) ≥140 mm Hg and diastolic BP <90 mm Hg, without any secondary causes of hypertension and antihypertensive drug therapy were selected for this study. Echocardiography and electrocardiography studies were implemented for demonstrating the development of cardiovascular complications. Results: Of 70 cases (41 males and 29 females), 64.3% were asymptomatic and 35.7% were symptomatic, with palpitation being the major symptom, 40% (28 cases) developed retinopathy, 45.71% developed increased left ventricular mass index (p=0.04), 18.57% had increased in LV volume (>90 ml/m2), 30% cases had regional wall motion abnormalities, 27.1% had reduced ejection fraction (<56%), and 52.66% showed LA enlargement in this study (p=0.048). Doppler measurements of diastolic filling were significant in patients with ISH with higher peak atrial velocity (A wave) of 79.71±11.79 cm/s and a lower ratio of peak early to atrial velocity of 0.82±0.29. Conclusion: This study demonstrates that elderly patients with ISH had a prevalence of concentric left ventricular hypertrophy (LVH) which was found to be more in female patients than in male patients followed by left atrial enlargement.

End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study

2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman
Keyword(s):  
Ventricular Hypertrophy ◽  
Organ Damage ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Age Group ◽  
Sectional Study ◽  
Isolated Systolic Hypertension ◽  
Cross Sectional ◽  
End Organ Damage ◽  
Common Risk Factors

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.

scholarly journals Evaluation of the clinical efficacy of antihypertensive drugs in elderly patients with isolated systolic hypertension

2010 ◽  
Vol 16 (4) ◽  
pp. 401-406
Author(s):  
V. E. Oleynikov ◽  
V. A. Budanova ◽  
L. I. Gusakovskaya ◽  
N. V. Sergatskaya
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Systolic Hypertension ◽  
Antihypertensive Drugs ◽  
Left Ventricular ◽  
Elderly Subjects ◽  
Isolated Systolic Hypertension ◽  
Diastolic Left Ventricular Function ◽  
Design And Methods ◽  
Heart Wall

Objective. To evaluate the antihypertensive and organoprotective effects of the calcium antagonist - slow release Nifedipine (Cordaflex RD) and diuretic Indapamid MR in patients with isolated systolic hypertension (ISH). Design and methods. 46 patients with ISH (66,2 ± 4,8 years) were included. Patients were divided into 2 clinical groups: 1st group (n = 26) took cordaflex RD, and 2nd group (n = 20) was given the Indapamide MR. The cardio- and angioprotective effects of the medications was evaluated. Results and conclusions. Cordaflex leads to the decrease of both systolic and diastolic blood pressure (SBP and DBP), whereas Indapamide influences SBP more, than DBP. Based on echocardiography results, both medications decreased the heart wall thickness, improved systolic and diastolic left ventricular function. Cordaflex RD significantly improved the diastolic left ventricular function. Both Cordaflex RD and Indapamide favorably influenced peripheral arteries endothelial function in elderly subjects with ISH. Both medications effectively reduced the index of the true stiffness CAVI.

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