End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study

2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.

1998 ◽  
Vol 27 (6) ◽  
pp. 787-791 ◽  
Author(s):  
Yousuke Takemura ◽  
Shogo Kikuchi ◽  
Hirofumi Takagi ◽  
Yutaka Inaba ◽  
Katsuya Nakagawa

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Carlos A Peñaherrera ◽  
Ruben E Peñaherrera ◽  
Maria C Duarte ◽  
Ernesto Peñaherrera

Background: metabolic syndrome (MetS) can chronically affect blood vessels, leading to cardiovascular disease. Techniques that assess arterial rigidity and age such as Arteriograph® can provide insight on blood vessel function. We aimed to evaluate arterial stiffness in patients with MetS. Methodology: cross-sectional study at Luis Vernaza hospital between November and December 2015. We included patients from the Cardiology Department with a full blood panel. We obtained clinical data for age, gender, history of smoking, hypertension, diabetes, and left ventricular hypertrophy, and measured abdominal girth and blood pressure. Using the Arteriograph®, we measured brachial and central augmentation indexes, central blood pressure, pulse wave velocity (PWV) and arterial age. We retrieved values for triglycerides, HDL, and glycemia from laboratory data. We used IDF criteria to diagnose MetS, but ALAD criteria were used to detect increased abdominal girth. A p value of <0.05 accepted for significance. Results: 95 patients were selected for analysis. 42 (44.2%) were female and 53 (55.8%) were male, with mean age of 61.7 years (SD 13.1). 58 (61.1%) of our patients had hypertension, 29 (30.5%) had diabetes, and 33 (34.7%) had ventricular hypertrophy. 47 (49.5%) of our patients had MetS. We found significant differences in arterial measurements in MetS vs. non-MetS patients, with higher values in the former (Table 1). We obtained non-significant results for the relationship between arterial age and MetS (p=0.32), even after adjusting for smoking (p=0.28) or ventricular hypertrophy (p=0.71). We found non-significant correlation between age and PWV (p=0.32), and found MetS to be significantly more common in women (p<0.001). Conclusion: MetS patients have a higher grade of arterial stiffness. Arterial age was not related to MetS, and it was more prevalent in women. Arteriograph® measurements are helpful to improve diagnosis and management of cardiovascular patients.


Author(s):  
K. Manoj Kumar ◽  
K. M. Jeyabalaji

Background: Prehypertension is a major public health concern. The condition is much prevalent in India and is often associated with other cardiovascular (CV) risk factors and independently increases the risk of hypertension and subsequent cardiovascular events. Several studies have shown microalbuminuria as a sensitive marker for predicting CV risk in pre-hypertensive. The objective of this study was to assess the prevalence of microalbuminuria in prehypertension and to determine its association with electrocardiogram (ECG) and echocardiographic (Echo) parameters indicative of CV risk.Methods: This cross-sectional study included a total of 75 subjects aged between 22 and 50 years, with prehypertension attending the medicine department of a tertiary care teaching hospital in Chennai, Tamil Nadu from April 2012 to November 2012. All the study subjects were evaluated with ECG and echo for cardiac changes. Statistical analysis was performed using SPSS software trial version-16 to determine the association of microalbuminuria with cardiac changes.Results: The prevalence of microalbuminuria among the included subjects was 60%. Mean value of urinary excretion of microalbuminuria was 90±2.1 µg/dl with a male preponderance in this study. Pre-hypertensive subjects with microalbuminuria had significant changes of left ventricular hypertrophy (LVH) as evident in ECG than those without microalbuminuria. Microalbuminuric prehypertensive subjects also had significant echocardiographic changes like LVH and diastolic dysfunction than those without microalbuminuria.Conclusions: The cardiovascular changes like left ventricular hypertrophy and diastolic dysfunction were evident in younger age among pre-hypertensives with microalbuminuria than those without microalbuminuria. 


2016 ◽  
Vol 216 ◽  
pp. 25-31 ◽  
Author(s):  
Yasuharu Tabara ◽  
Katsuhiko Kohara ◽  
Masayuki Ochi ◽  
Yoko Okada ◽  
Maya Ohara ◽  
...  

2019 ◽  
Vol 8 (2) ◽  
pp. 345-356 ◽  
Author(s):  
Theodora W. Elffers ◽  
Stella Trompet ◽  
Renée de Mutsert ◽  
Arie C. Maan ◽  
Hildo J. Lamb ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document