scholarly journals Effective interventions to improve medication adherence in Type 2 diabetes: a systematic review

2014 ◽  
Vol 4 (1) ◽  
pp. 29-48 ◽  
Author(s):  
Joni L Strom Williams ◽  
Rebekah J Walker ◽  
Brittany L Smalls ◽  
Jennifer A Campbell ◽  
Leonard E Egede
2020 ◽  
pp. 106002802095072
Author(s):  
Jennifer M. Bingham ◽  
Melissa Black ◽  
Elizabeth J. Anderson ◽  
Yawen Li ◽  
Natalie Toselli ◽  
...  

Objective: To describe telehealth interventions and determine their effect on medication adherence for patients with type 2 diabetes, hypertension, and/or dyslipidemia. Data Sources: PubMed/MEDLINE, EMBASE, Cochrane, CINAHL Plus, PsycINFO, Academic Search Ultimate, International Pharmaceutical Abstracts, Scopus, Web of Science, WHO Global Index Medicus, association websites, and gray literature were searched from January 1, 1998, to December 31, 2019. Study Selection and Data Extraction: Eligible studies reported eHealth, mobile health, and telehealth interventions for adult patients prescribed medications for chronic condition management (eg, type 2 diabetes, hypertension, and/or dyslipidemia). Studies were required to evaluate medication adherence outcomes (eg, medication possession ratio [MPR], proportion of days covered (PDC)]. Randomized controlled trials, cohort studies, and controlled before-and-after studies were included. Multiple reviewers independently extracted data and evaluated risk of bias. Data Synthesis: Of 8693 studies identified, 13 reported either an MPR or PDC and were included in the systematic review. The systematic review demonstrated that electronic health (eHealth) and telehealth interventions were successful at improving medication adherence, whereas mobile health interventions did not improve medication adherence. Relevance to Patient Care and Clinical Practice: This systematic review highlighted the available research and findings of studies assessing interventions to improve medication nonadherence among patients with type 2 diabetes, hypertension, and/or dyslipidemia. The evaluated findings lend support to the need for targeted medication adherence interventions based on patient population and practice settings. Conclusions: Telehealth modalities include telephonic outreach and specialized tools designed to increase health literacy. eHealth and telehealth medication adherence interventions were associated with improved MPR and/or PDC rates.


2019 ◽  
Vol 1 (3) ◽  
pp. 107
Author(s):  
Sulistyo Andarmoyo ◽  
Harmy Bin Mohamed Yusoff ◽  
Berhanudin Bin Abdullah ◽  
Yuzana Binti Mohd Yusop

Adherence has an important role in therapy management in patients with type 2 Diabetes Mellitus. This research is to identify and analyze factors related to medication adherence. The design used in this study was a descriptive-analytic design with a cross-sectional approach. The population is type 2 Diabetes Mellitus sufferers of Prolanis Group in Primary Health Care Facilities in the Ponorogo Regency. A sample of 180 respondents was taken by purposive sampling technique. Variable X includes age, gender, education, occupation, income, and length of suffering. Variable Y was medication compliance with type 2 Diabetes Mellitus patients. Data collection used a Morisky Medication Adherence (MMAS-8) questionnaire and was analyzed using the Chi-Square test with a significant level of α <0.05. From the results of the study, it was found that the factors of age, sex, education, employment, income and duration of suffering had a significant relationship with medication adherence for patients with type 2 diabetes mellitus. It is expected that health services develop family and community-based service management. Researchers are further advised to develop programs to improve medication adherence.


2021 ◽  
pp. 193229682110600
Author(s):  
Tarani Prakash Shrivastava ◽  
Shikha Goswami ◽  
Rahul Gupta ◽  
Ramesh K. Goyal

Background: Medication adherence in type 2 diabetes mellitus (T2DM) patients is often suboptimal resulting in complications. There has been a growing interest in using mobile apps for improving medication adherence. Objective: The objective of this work was to systematically review the clinical trials that have used mobile app–based interventions in T2DM patients for improving medication adherence. Methodology: A systematic search was performed to identify published clinical trials between January 2008 and December 2020 in databases—PubMed, Cochrane Library, and Google Scholar. All studies were assessed for risk of bias using quality rating tool from the Cochrane Handbook for Systematic Reviews of Interventions. Results: Seven clinical studies having 649 participants were studied. The median sample size was 58 (range = 41-247) and the median age of participants was 53.2 (range = 48-69.4) years. All studies showed improvements in adherence; however, only three studies reported statically significant improvements in adherence measures. Selected studies were deemed as unclear in their risk of bias and the most common source of risk of bias among the studies was the absence of objective outcome assessment. Conclusions: Mobile apps appear to be effective interventions to help improve medication adherence in T2DM patients compared with conventional care strategies. The features of the App to improvise medical adherence cannot be defined based on the meta-analysis because of heterogeneity of study designs and less number of sample size. Systematically planned studies would set up applicability of mobile apps in the clinical management of T2DM.


2022 ◽  
Vol Volume 16 ◽  
pp. 95-104
Author(s):  
Leonard H Epstein ◽  
Tatiana Jimenez-Knight ◽  
Anna M Honan ◽  
Rocco A Paluch ◽  
Warren K Bickel

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Olayinka O. Shiyanbola ◽  
Betty L. Kaiser ◽  
Gay R. Thomas ◽  
Adati Tarfa

Abstract Background The Peers Supporting Health Literacy, Self-efficacy, Self-Advocacy, and Adherence (Peers LEAD) program is a culturally tailored educational-behavioral 8-week intervention that addressed psychosocial and sociocultural barriers to diabetes medication adherence in African Americans. A brief 3-week version of the Peers LEAD intervention used a community engagement approach to examine the feasibility and acceptability of the intervention amongst patient stakeholders. Main body African Americans who were adherent to their diabetes medicines were paired with those who were non-adherent to their medicines. Together, they participated in the group and phone-based medication adherence intervention. Input from this brief intervention was important for the design of the remainder weeks of the 8-week program. The intervention targeted negative beliefs about diabetes, use of diabetes medicines, and offering culturally tailored peer support to improve medication adherence in African Americans. To receive input in the development and implementation of the program, we worked with community advisors and a peer ambassador board of African Americans who were adherent to their diabetes medicines. The peer ambassador board and community advisors reviewed intervention materials to ensure they were understandable and appropriate for the community. As well, they provided feedback on the process for intervention delivery. Conclusion The active engagement of the peer ambassador board and community advisors led to a revised intervention process and materials for a medication adherence program for African Americans with type 2 diabetes.


2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Henrique Ceretta Oliveira ◽  
Daisuke Hayashi Neto ◽  
Samantha Dalbosco Lins Carvalho ◽  
Rita de Cássia Lopes Barros ◽  
Mayza Luzia dos Santos Neves ◽  
...  

Abstract Background The pharmacological treatment of cardiovascular diseases and type 2 diabetes mellitus reduces the risk of cardiovascular events.; however, most patients do not adhere to the treatment. There are several self-reported measures for assessing medication adherence. Identifying the instruments with the best psychometric evidence is essential for selecting an accurate measure. The aim of this study is to critically assess, compare and synthesize the quality of the measurement properties of patient-reported outcome measures to access medication adherence among patients with cardiovascular diseases and/or type 2 diabetes mellitus. Methods This protocol is reported according to Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) and the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidelines. The following databases will be searched: Web of Science, SCOPUS, PubMed, CINAHL, EMBASE, LILACS, PsycINFO and ProQuest. Discussion This review will provide a detailed assessment of the measurement properties of self-reported medication adherence instruments in patients with cardiovascular diseases and/or type 2 diabetes mellitus to support clinical practice and research. Systematic review registration PROSPERO CRD42019129109.


2021 ◽  
Vol 8 ◽  
pp. 237437352110343
Author(s):  
EE Onwuchuluba ◽  
OO Oyetunde ◽  
RO Soremekun

Adherence to antidiabetic medications (ADMs) remains a serious challenge among type 2 diabetes mellitus (T2DM) patients. Factors affecting medication adherence are not fully understood in Nigeria. This qualitative study explored patients’ views on barriers and facilitators of medication adherence. Data collection was through face-to-face, semistructured, in-depth interviews conducted on 25 purposively sampled patients attending a public tertiary hospital. The interviews were audio recorded, transcribed verbatim, and analyzed using thematic analysis based on socioecological framework. NVIVO version 10 identified more codes. Most commonly identified barriers were organizational (clinic structure), personal (perception of T2DM as a dangerous illness), interpersonal (lack of spousal support), and community (concerns about taking ADMs in social gatherings). It was observed that female patients received more spousal support than the males. The facilitators of adherence include perceiving medication-taking a routine, the need to live longer, having savings for ADMs, purchasing medications to last until the next clinic visit. This study identified barriers and facilitators unique to Nigerian T2DM patients. Interventions anchored on these factors would improve medication adherence.


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