Nuclear medicine and anatomic pathology in personalized medicine: a challenging alliance

2018 ◽  
Vol 15 (6) ◽  
pp. 457-459 ◽  
Author(s):  
Nicoletta Urbano ◽  
Manuel Scimeca ◽  
Elena Bonanno ◽  
Orazio Schillaci
Keyword(s):  
Nuclear Medicine ◽  
Personalized Medicine ◽  
Anatomic Pathology

scholarly journals (Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer

2020 ◽  
Vol 13 (3) ◽  
pp. 39
Author(s):  
Irina Velikyan
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Nuclear Medicine ◽  
Personalized Medicine ◽  
Patient Management ◽  
Neuroendocrine Neoplasms ◽  
Medicine Development ◽  
Oncological Patients

The role of nuclear medicine in the management of oncological patients has expanded during last two decades. The number of radiopharmaceuticals contributing to the realization of theranostics/radiotheranostics in the context of personalized medicine is increasing. This review is focused on the examples of targeted (radio)pharmaceuticals for the imaging and therapy of neuroendocrine neoplasms (NENs), prostate cancer, and breast cancer. These examples strongly demonstrate the tendency of nuclear medicine development towards personalized medicine.

scholarly journals Special Issue ”Instruments and Methods for Cyclotron Produced Radioisotopes”

Instruments ◽  
2019 ◽  
Vol 3 (4) ◽  
pp. 60
Author(s):  
Saverio Braccini ◽  
Francisco Alves
Keyword(s):  
Nuclear Medicine ◽  
Personalized Medicine ◽  
Crucial Role ◽  
Particle Physics ◽  
Radioisotope Production ◽  
Science And Society ◽  
Special Issue ◽  
And Personalized Medicine ◽  
Diagnostics And Therapy ◽  
The Way

The 17th Workshop on Targets and Target Chemistry (WTTC17) was held in Coimbra (Portugal) on 27–31 August 2018. A few months before, the 13th Workshop of the European Cyclotron Network (CYCLEUR) took place in Lisbon (Portugal) on 23–24 November 2017. These two events reassembled major experts in the field of radioisotope production, targets, target chemistry and cyclotrons. In the last few years, significant advances have been obtained in these fields with direct implications for science and society. Instruments and methods, originally developed for nuclear and particle physics, played a crucial role and remarkable developments are on-going. The production of novel radioisotopes for both diagnostics and therapy is expected to produce a breakthrough in nuclear medicine in the next years, paving the way towards theranostics and personalized medicine. This Special Issue presents a collection of original scientific contributions on the latest developments on instruments and methods for medical and research cyclotrons as well as on target and target chemistry for the production of radioisotopes.

scholarly journals Management of oncological patients in the digital era: anatomic pathology and nuclear medicine teamwork

2018 ◽  
Vol 14 (11) ◽  
pp. 1013-1015 ◽  
Author(s):  
Manuel Scimeca ◽  
Nicoletta Urbano ◽  
Rita Bonfiglio ◽  
Orazio Schillaci ◽  
Elena Bonanno
Keyword(s):  
Nuclear Medicine ◽  
Anatomic Pathology ◽  
Digital Era ◽  
Oncological Patients

Discovery of rhenium and masurium (technetium) by Ida Noddack-Tacke and Walter Noddack

2015 ◽  
Vol 54 (06) ◽  
pp. N50-N54 ◽  
Author(s):  
F. Stelzner ◽  
F. F. Knapp ◽  
H.-J. Biersack
Keyword(s):  
Nuclear Medicine ◽  
Personalized Medicine ◽  
Early Identification ◽  
Technetium 99M ◽  
German Science ◽  
History Of ◽  
Gamma Emitter

SummaryThe history of the early identification of elements and their designation to the Mendeleev Table of the Elements was an important chapter in German science in which Ida (1896-1978) and Walter (1893-1960) Noddack played an important role in the first identification of rhenium (element 75, 1925) and technetium (element 43, 1933). In 1934 Ida Noddack was also the first to predict fission of uranium into smaller atoms. Although the Noddacks did not for some time later receive the recognition for the first identification of technetium-99m, their efforts have appropriately more recently been recognized. The discoveries of these early pioneers are even more astounding in light of the limited technologies and resources which were available during this period. The Noddack discoveries of elements 43 and 75 are related to the sub sequent use of rhenium-188 (beta/ gamma emitter) and technetium-99m (gamma emitter) in nuclear medicine. In particular, the theranostic relationship between these two generator-derived radioisotopes has been demonstrated and offers new opportunities in the current era of personalized medicine.

scholarly journals Theranostics in Nuclear Medicine Practice

2017 ◽  
Author(s):  
Anna Yordanova ◽  
Elisabeth Eppard ◽  
Stefan Kürpig ◽  
Stefan Schönberger ◽  
Maria Gonzalez-Carmona ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
Thyroid Cancer ◽  
Personalized Medicine ◽  
Targeted Therapies ◽  
Radioiodine Therapy ◽  
Diagnostic Techniques ◽  
Molecular Targeting ◽  
Theranostic Agents ◽  
Nuclear Medicine Practice ◽  
Diagnostics And Therapy

The importance of personalized medicine is growing, since there is an urged need to avoid unnecessary and expensive treatments. In nuclear medicine, the theranostic approach is an established tool for a specific molecular targeting in means of diagnostics and therapy. The visualisation of potential targets can help to predict if a patient would benefit from a particular treatment or not. Thanks to the quick development of radiopharmaceuticals and diagnostic techniques, the use of theranostic agents is constantly rising. In this article important milestones of nuclear therapies and diagnostics in the context of theranostics are highlighted. It begins with the well-known radioiodine therapy in patients with thyroid cancer and then guides through different approaches for the treatment of advanced cancer with targeted therapies. The aim of this review is to provide a summary of background knowledge, current applications and advantages of targeted therapies and imaging in nuclear medicine practice.

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