STRUCTURE AND CONTENT CHARACTERISTICS OF THE DISSERTATION AS A GENRE OF WRITTEN SCIENTIFIC MEDICAL TEXT IN ENGLISH

Статья посвящена описанию структурных и содержательных характеристик трактатов и диссертаций XVII века, а также современной диссертации на английском языке. Выполняется сравнительный анализ научных трудов на начальном этапе национализации медицинской науки в Великой Британии, и современных диссертаций - в период функционирования английского языка как lingua franca в мировой науке. This research is devoted to the linguistic study of English dissertations in medicine. The scientific works are represented by the genre of a written scientific medical text in English with the characteristic of functional features and they were defended in Great Britain. Diachronic research of linguistic phenomena involves the study of written scientific works and they belong to different periods of British history and medical science and it is important to correlate the studied phenomenon at different stages with the medicine development.

Research on the Drivers of Entrepreneurship Education Performance of Medical Students in the Digital Age

COVID-19 has made the entire society pay more attention to medical students training. Medicine development is inseparable from the spirit of innovation, focusing on cultivating medical students' innovative awareness and improving entrepreneurship education performance, which has an irreplaceable effect on both the students themselves and the society. This study is based on the ridge regression model to study the driving factors of the entrepreneurship education performance of medical students. Compared with traditional multiple regression, it can improve the consistency of parameter estimation and obtain more realistic results. Based on a large sample of empirical survey data of 24,677 medical students in China, this study analyzed the driving factors of the entrepreneurship education performance of medical students and found that medical students of different genders have differences in entrepreneurship education performance; the digital economy impacts entrepreneurship education performance of medical students; entrepreneurship course, entrepreneurship faculty, entrepreneurship competition, entrepreneurship practice, and entrepreneurship policy have a driving effect on the entrepreneurship education performance of medical students. Meanwhile, the impact of entrepreneurship policy is the most obvious, followed by entrepreneurship practice and entrepreneurship competition, followed by entrepreneurship course and entrepreneurship faculty.

Institutionalizing Reflexivity for Sustainability: Two Cases in Health Care

Unsustainability in health care comprises diminishing returns and misalignment between the health care regime and the needs of the population. To deal with complex sustainability problems, niche solutions can be collaboratively designed and implemented through reflexive methods. For second-order sustainability, however, the institutionalization of the reflexive element itself is also needed. This paper aims to provide insight into the possibilities of embedding reflexivity into institutions to support second-order sustainability by reporting on two consecutive participatory research programs that sought to address unsustainability in terms of misalignment and diminishing returns. The first case study reflexively monitored the system’s innovation toward an integrated perinatal care system. Reflection within the project and implementation was supported successfully, but for stronger embedding and institutionalization, greater alignment of the reflexive practices with regime standards was needed. Building on these lessons, the second case study, which was part of the IMI-PARADIGM consortium, collaboratively built a structured tool to monitor and evaluate “the return on engagement” in medicine development. To institutionalize reflexivity, the creation of “reflexive standards” together with regime actors appears to be most promising. Broader and deeper institutionalization of reflexive standards can be attained by building enforcement structures for reflexive standards in the collaborative process as part of the reflexive methodologies for addressing complex sustainability problems.

A Review on Protein Misfolding Diseases and therapeutics for preventing Diseases

Background: Protein misfolding sicknesses are the gathering of irresistible lethal neuro and non-neurodegenerative infections and in ebb and flow researchers and specialists accepted that unusual folding of protein is the essential or main key of such illnesses are Alzheimer's infections, Parkinson's diseases, Huntington's sickness, Creutzfeldt-Jakob infection, cystic fibrosis, Gaucher's infection and numerous other degenerative and neurodegenerative problems. The motive of this review article is to gave a detailed of the existing structural information for prion and prion protein and also we will trying to find out their preventing root causes with respect to structural information of prions within the context of what is known about the protein misfolding diseases. Objective: This article presents a brief overview of research on the use of these therapeutics for the treatment or improvement in prion diseases or protein misfolding. Material and Methods: This article begins with the brief introduction about protein misfolding diseases or infections and the therapeutic materials which are used in researches or explain this article (pentosan polysulfate, Quinacrine, Doxycycline, Chaperone based therapy, Resveratrol and curcumin) etc. Results and Conclusions: In this present context of protein misfolding/prion diseases diagonsis.Therapeutic approaches predicts that person infected with prion diseases prolongs the survival time of the patient and improvement in the conditions of the prion diseased infected patient which provides good result for future medicine development. Keywords: Amyloid, Beta-sheet, neurodegenerative, prion, protein misfolding, therapeutics etc

Plants Used for Ethno-veterinary Practices by Tribes of Kambakkam of Eastern Ghats

The study reports the surveyed of medicinal plants used by of village Tribe people of Kambakkam Forest (Easternghats), Andhra Pradesh in ethno-veterinary practices. During this study information about the ethno-veterinary plants were collected and preserved as herbarium specimens by follows the standard procedure. The plants were identified with help of some standard Floras. The specimens were deposited in the herbarium of Department of Plant Biology and Plant Biotechnology, Loganatha Narayanasamy Government College, Ponneri, Thiruvallur District. During the survey it was noted 23 plants were traditionally used by various animal diseases such as Inflammation, wound healing, indigestion, dysentery, fever, swelling, bone fracture, diarrhea, cold, cough, pneumonia, constipation, antimicrobial and milk yielding properties. The information provided in this study would bring new medicine development of ecofriedly, effective medicines to control human diseases in the future perspective. This study may be useful to protect and conserve the medicinal plants of Kambakkam Forest.

Targeting Gut–Liver Axis for Treatment of Liver Fibrosis and Portal Hypertension

Antifibrotic therapies for the treatment of liver fibrosis represent an unconquered area of drug development. The significant involvement of the gut microbiota as a driving force in a multitude of liver disease, be it pathogenesis or fibrotic progression, suggest that targeting the gut–liver axis, relevant signaling pathways, and/or manipulation of the gut’s commensal microbial composition and its metabolites may offer opportunities for biomarker discovery, novel therapies and personalized medicine development. Here, we review potential links between bacterial translocation and deficits of host-microbiome compartmentalization and liver fibrosis that occur in settings of advanced chronic liver disease. We discuss established and emerging therapeutic strategies, translated from our current knowledge of the gut–liver axis, targeted at restoring intestinal eubiosis, ameliorating hepatic fibrosis and rising portal hypertension that characterize and define the course of decompensated cirrhosis.

Concept of «constitutional and legal mechanism for ensuring the right to transplantation in Ukraine» and its elements

The article is devoted to the issue of the concept of «constitutional and legal mechanism for ensuring the right to transplantation in Ukraine». The author’s definition of the concept «constitutional and legal mechanism for ensuring the right to transplantation in Ukraine» is formulated. Some elements of the constitutional and legal mechanism for ensuring the right to transplantation in Ukraine are determined.In the process of development of Ukraine as a democratic and legal state, European integration of Ukraine, scientific and technological progress, evolution of the fourth generation of human rights, development of medicine, development of transplantation in Ukraine, research on the defence of the constitutional and legal mechanism of ensuring the right to transplantation in Ukraine.The right to transplantation belongs to the fourth generation of human rights, which has been actively developing in recent years.The issue of ensuring the right to transplantation in Ukraine is an important element of the constitutional law of Ukraine.Ensuring the right to transplantation in Ukraine is an integral part of a single integrated human rights system in Ukraine.The constitutional and legal mechanism for ensuring the right to transplantation in Ukraine is a set of norms and principles of law on transplantation in Ukraine, as well as the system of authorized entities and their activities in the field of realisation of the right to transplantation in Ukraine, its guarantee and protection. The main elements of the constitutional and legal mechanism for ensuring the right to transplantation in Ukraine are:1. Realization of the right to transplantation in Ukraine.2. Protection of the right to transplantation in Ukraine.3. Guarantees of the right to transplantation in Ukraine.The constitutional and legal mechanism for ensuring the right to transplantation in Ukraine is an integral part of a single integrated system of the constitutional and legal mechanism for ensuring human rights in Ukraine.