Malarial Epidemiology among Patients in Al-Medina Al-Munawara, KSA

2021 ◽  
Vol 11 (6) ◽  
pp. 97-102
Author(s):  
Shady Mohammad Raji Al-Hussayni ◽  
Sami Oudah Eid Al-Harbi ◽  
Omar Hassan Amer
Keyword(s):  
Case Series ◽  
Plasmodium Species ◽  
Retrospective Case ◽  
Malaria Burden ◽  
Case Series Study ◽  
Male Patients ◽  
Clinical Tools ◽  
Collection Form ◽  
Series Study ◽  
Important Disease

Worldwide, malaria is the most important disease caused by parasites and responsible for a yearly estimation of 225 million clinical cases. The risk of the disease covers almost half of the world’s population and the annual death has been estimated as 800.000. Children under five years of age are mainly affected. Pregnant women and adults with immunosuppression become victims of cerebral manifestations or anaemia and frequently die. Almost 40% of the world's population is at risk to acquire the infection. Human malaria is caused by four Plasmodium species among which the most prevalent is Plasmodium falciparum. Because of the higher global prevalence, morbidity and mortality rate of P. falciparum, most research efforts on malaria pathogenesis have been focused on this species. Recent studies have reported the clinical outcomes that originate from regions where P. falciparum and P. vivax are equally prevalent. This in turn could make the clinical tools inappropriate for use in managing vivax mono infections. Thus, the present study was aimed to identify the epidemiology and clinical features of the malarial cases of the Referral laboratory, Al Madinah, Saudi Arabia. A retrospective case series study was conducted among the patients reported from January 2016 to December 2016 using a specially designed data collection form. Out of the 182 confirmed cases, 143 were non-saudi and 39 were Saudi cases. Most of the cases reported in the month of September due to seasonal change. Gender distribution showed a higher dominance of male patients compared to females. No cases were reported to be caused due to P.malariae. The predominant species was found to be P.Vivax (87%) while P.falciparum with only 13% incidence. Further investigations in large sample sizes are recommended to explore the other aspects in reducing the malaria burden.

Electrophysiological effects and clinical utility of propafenone in children

2021 ◽  
pp. 1-5
Author(s):  
Manavotam Singh ◽  
Keore McKenzie ◽  
Mark L. Hudak ◽  
Anil K. Gehi ◽  
Sunita J. Ferns
Keyword(s):  
Case Series ◽  
Clinical Effectiveness ◽  
Retrospective Case ◽  
Cardiac Side Effects ◽  
Cardiac Depression ◽  
Case Series Study ◽  
Baseline Characteristics ◽  
Antiarrhythmic Medication ◽  
Electrophysiological Effects ◽  
Series Study

Abstract Aim: This retrospective case series study sought to describe the safety and clinical effectiveness of propafenone for the control of arrhythmias in children with and without CHD or cardiomyopathy. Methods: We reviewed baseline characteristics and subsequent outcomes in a group of 63 children treated with propafenone at 2 sites over a 15-year period Therapy was considered effective if no clinically apparent breakthrough episodes of arrhythmias were noted on the medication. Results: Sixty-three patients (29 males) were initiated on propafenone at a median age of 2.3 years. CHD or cardiomyopathy was noted in 21/63 (33%). There were no significant differences between demographics, clinical backgrounds, antiarrhythmic details, side effect profiles, and outcomes between children with normal hearts and children with CHD or cardiomyopathy. Cardiac depression at the initiation of propafenone was more common amongst children with CHD or cardiomyopathy compared to children with normal hearts. Systemic ventricular function was diminished in 15/63 patients (24%) prior to starting propafenone and improved in 8/15 (53%) of patients once better rhythm control was achieved. Other than one child in whom medication was stopped due to gastroesophageal reflux, no other child experienced significant systemic or cardiac side effects during treatment with propafenone. Propafenone achieved nearly equal success in controlling arrhythmias in both children with normal hearts and children with congenital heart disease or cardiomyopathy (90% versus 86%, p = 0.88). Conclusion: Propafenone is a safe and effective antiarrhythmic medication in children.

scholarly journals GYNAECOMASTIA

2010 ◽  
Vol 17 (02) ◽  
pp. 205-210
Author(s):  
ASIYA SHABBIR ◽  
TARIQ MAHMOOD REHAN ◽  
SHAHID Hussain Jaffery ◽  
Muhammad Ubaidullah Baig
Keyword(s):  
Benign Lesion ◽  
Case Series ◽  
Spontaneous Resolution ◽  
Subcutaneous Mastectomy ◽  
Appropriate Treatment ◽  
Case Series Study ◽  
Causative Factors ◽  
Male Patients ◽  
Series Study ◽  
Surgical Unit

Objectives: To determine the causative factors and management of Gynaecomastia. Study Design: Observational case series study. Place and Duration of Study: Surgical Unit-1 Bahawal Victoria Hospital Bahawalpur, from 1st January 200 till 31st December 2007. Patient and Methods: Thirty male patients having breast swelling were included in this study. Relevant history was obtained. Appropriate physical examination was performed. Necessary investigations were done and after making a diagnosis appropriate treatment was done. A total of 30 patients were studied in the study period of 18 months. Those male patients who were having breast lesion other than benign enlargement (e.g. Ca. Breast, Breast/Abscess) were not included in the study. Necessary investigations were done. Subcutaneous Mastectomy was performed. Results: The most common age group developing gynaecomastia was of 20-30 years (60%). Bilateral gynaecomastia was observed in 76.66% and unilateral gynaecomastia in 23.33%. Idiopathic gynaecomastia was observed in 73.33% cases. Medical treatment was given with tamoxifen 10mg twice a day for the period of three months in 6 case (20%) and this remained effective in 5 case (83.33%). Subcutaneous mastectomy was performed in 17 cases (56.66%). Post-operative complications were seen in 4 cases (23.52%), the most common complication being wound hematoma in 2 cases (11.76%). Most of the patients (88.9%) were fully satisfied with the results of subcutaneous mastectomy. Conclusion: Gynaecomastia is the most common benign lesion of the male breast. As far as physiological gynaecomastia is concerned, patients should be observed for at least 2 years from the onset of their condition. In most of the cases spontaneous resolution occurs. Surgical treatment should be planned in whom spontaneous resolution does not occur. Surgery remains the mainstay of therapy and is frequently indicated for psychological and cosmetic reasons. 

NEAR FATAL AMITRAZ: A NOT SO UNCOMMON POISONING

2021 ◽  
pp. 42-43
Author(s):  
Rohan J Desai ◽  
Prasad Ugargol
Keyword(s):  
Mechanical Ventilation ◽  
Respiratory Failure ◽  
Clinical Features ◽  
Case Series ◽  
Agricultural Product ◽  
Common Symptom ◽  
Retrospective Case ◽  
Case Series Study ◽  
Cns Depression ◽  
Series Study

Background: Amitraz is a pharmaceutical, veterinary, and agricultural product which is used worldwide to control ectoparasites in animals. Its widespread use has led to increased cases of poisoning in rural parts of India. Aim: To study the clinical features, complications, laboratory abnormalities and outcome of the patients with acute amitraz intoxication. Methodology: The study is a retrospective case series study conducted in HSK hospital between the period of Feb 2019 and May 2020. Results: A total of 11 patients were analysed and results revealed CNS depression and vomiting in 8 of those patients with 1 patient with respiratory failure requiring mechanical ventilation. Conclusion: Amitraz poisoning appears to be severe with CNS depression being the most common symptom. But most patients stabilise and recover quickly. Patients should be monitored for respiratory failure as it is a dreadful complication. Treatment is symptomatic as no antidote is available.

scholarly journals Infection of the central nervous system caused by varicella zoster virus reactivation: a retrospective case series study

2013 ◽  
Vol 17 (7) ◽  
pp. e529-e534 ◽  
Author(s):  
Juan Carlos Lozano Becerra ◽  
Robert Sieber ◽  
Gladys Martinetti ◽  
Silvia Tschuor Costa ◽  
Pascal Meylan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Varicella Zoster Virus ◽  
Case Series ◽  
Virus Reactivation ◽  
Retrospective Case ◽  
Varicella Zoster ◽  
Case Series Study ◽  
The Central Nervous System ◽  
Series Study
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