scholarly journals INTRAOSSEOUS LESION OF PHALANX: TWO SIMILAR CASES BUT NOT THE SAME

2019 ◽  
Vol 22 (2) ◽  
pp. 1-3
Author(s):  
Jayaletchumi Gunasagaran ◽  
Weng Hong Chung ◽  
Sachin Shivdas ◽  
Shams Amir ◽  
Saw Sian Khoo ◽  
...  
Keyword(s):  
Intraosseous Lesion

scholarly journals Fibrous Meningioma with Skull Invasion

2019 ◽  
Vol 10 (04) ◽  
pp. 707-710
Author(s):  
Shinya Ichimura ◽  
Kento Takahara ◽  
Koji Fujii
Keyword(s):  
Present Report ◽  
Bone Lesion ◽  
Parietal Bone ◽  
Matrix Metalloproteinase 2 ◽  
Gadolinium Enhancement ◽  
Bone Invasion ◽  
Weighted Magnetic Resonance Imaging ◽  
The Right ◽  
Intraosseous Lesion ◽  
Aggressive Clinical Behavior

AbstractIn patients with meningiomas, the presence of skull invasion is known to be a predictor of aggressive clinical behavior, which may negatively influence patient outcomes. In the present report, we discuss a case of fibrous meningioma with skull invasion. A 42-year-old woman was referred to our department presenting with hyperostosis in the right parietal bone. T1-weighted magnetic resonance imaging with gadolinium enhancement revealed prominent enhancement of the intraosseous lesion and dura mater. Following the removal of the tumor body and bone lesion, we performed immunohistochemical staining for osteopontin (OPN), matrix metalloproteinase- 2 (MMP2), and integrin β-1 (CD29). The tumor body was immunoreactive for OPN and CD29, but not MMP2, whereas, the bone lesion was immunoreactive for all the three antigens. The present case suggests that OPN, MMP2, and CD29 play key regulatory roles in bone invasion.

Pathology Consultation Squamous Odontogenic Tumor

1993 ◽  
Vol 102 (10) ◽  
pp. 823-824 ◽  
Author(s):  
John G. Batsakis ◽  
Karen R. Cleary
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Odontogenic Tumor ◽  
Surgical Removal ◽  
Jaw Bones ◽  
Malignant Alteration ◽  
Intraosseous Lesion

The squamous odontogenic tumor is almost exclusively an intraosseous lesion of the jaw bones. Only 1 extraosseous variant has been reported. The tumor is histologically benign, with only occasional recurrences after surgical removal. Malignant alteration is unknown, but the lesion must be distinguished from intraosseous squamous cell carcinomas.

scholarly journals Central Giant Cell Granuloma

2019 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
Nilotpol Kashyap ◽  
Manisha Upadhyay ◽  
Rupam Tripathi ◽  
Pallavi Pawar ◽  
Ranjeet Kumar Prasad Sah ◽  
...  
Keyword(s):  
Giant Cell ◽  
Fibrous Tissue ◽  
Giant Cells ◽  
World Health ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Bony Lesion ◽  
Benign Tumours ◽  
Health Organization ◽  
Intraosseous Lesion

Central giant cell granuloma (central giant cell granuloma) is an uncommon benign bony lesion that occurs in the mandible and maxilla and accounts for approximately 7% of all benign tumours of the jaws [1]. The World Health Organization (WHO) has defined central giant cell granuloma as an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of haemorrhage, aggregations of multinucleated giant cells and occasional trabeculae of woven bone [2]. Central giant cell granuloma occurs predominantly in children or young adults, with approximately 75%of cases presenting before 30 years of age although presentation can occur at any age [3]. Females are affected more frequently than males, with a ratio of 2:1

Central Giant Cell Granuloma: A Narrative Review of Radiological Features and Differential Diagnosis

2020 ◽  
Vol 3 (2) ◽  
pp. 01-05
Author(s):  
Cinzia Casu
Keyword(s):  
Giant Cell ◽  
Fibrous Tissue ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Genetic Syndromes ◽  
Radiographic Appearance ◽  
Central Giant Cell Granuloma ◽  
Jaw Bones ◽  
Aneurysmal Bone Cysts ◽  
Intraosseous Lesion

The Central Giant Cell Granuloma is an uncommon lesion, accounting less than 7% of all benign jaw lesions. In 1953, Jaffe was the first to describe these lesions as a giant cell reparative granuloma of the jaw bones, and in 1971, thanks to Pindborg and Kramer, it was included in the current nomenclature. The aetiology of CGCG is unknown, there is also a peripheral type that some authors consider the most common in maxillary bones. WHO defines CGCG as an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells, and some trabeculae of woven bone. The radiographic appearance of CGCGs is not pathognomonic. CGCGs should be differentiated from other lesions of the jaws such as Brown’s tumour of hyperparathyroidism, fibrous dysplasia, aneurysmal bone cysts, giant cell tumours, fibro-osseous lesions, and other malignancies that arise in the jaw bones. Furthermore, it needs to be differentiated even from some genetic syndromes, such as Cherubism, type 1-neurofibromatosis and Noonan’s syndrome. The aim of this study is to focus on radiographic features of CGCG in order to achieve an appropriate tool for diagnosis.

scholarly journals MRI-guided segmental sternectomy for impalpable intraosseous lesion

2020 ◽  
Vol 12 (1) ◽  
pp. 42-44
Author(s):  
Francesco Petrella ◽  
Monica Casiraghi ◽  
Niccolò Filippi ◽  
Riccardo Orlandi ◽  
Andrea Alliata ◽  
...  
Keyword(s):  
Mri Guided ◽  
Intraosseous Lesion

Central Giant Cell Granuloma of the Mandible: A Rare Presentation

2012 ◽  
Vol 3 (3) ◽  
pp. 172-174
Author(s):  
Sunita Malik ◽  
Virender Singh ◽  
Gurdarshan Singh ◽  
Nisha Dahiya
Keyword(s):  
Giant Cell ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Rare Presentation ◽  
Central Giant Cell Granuloma ◽  
Woven Bone ◽  
Local Trauma ◽  
Mandibular Body ◽  
Intraosseous Lesion ◽  
Age Range

ABSTRACT Central giant cell granuloma (CGCG) is an intraosseous lesion consisting of cellular fibrosis tissue that contains multiple foci of hemorrhage, multinucleated giant cells and trabeculas of woven bone. This lesion accounts for less than 7% of all benign jaw tumors. Jaffe considered it as a locally reparative reaction of bone which can be possibly due to either an inflammatory response, hemorrhage or local trauma. Females are affected more frequently than males. It occurs over a wide age range. It has been reported that this lesion is diagnosed during the first two decades of life in approximately 48% of cases and 60% of cases are evident before the age of 30. It is considerably more common in the mandible than in maxilla. The majority of the lesions occur in the molar and premolar area, and some of these extend to the ascending ramus. The presence of giant cell granuloma in the mandibular body area, entire ramus, condyle and coronoid creates a diagnostic and therapeutic challenge for the oral and maxillofacial surgeons. The purpose of this report is to describe an unusual presentation of CGCG involving mandibular body, ramus, condylar and coronoid processes and to discuss the differential diagnosis, radiographic presentation and management of this lesion. How to cite this article Malik S, Singh V, Singh G, Dahiya N. Central Giant Cell Granuloma of the Mandible: A Rare Presentation. Int J Head and Neck Surg 2012;3(3):172-174.

scholarly journals Multiple Odontogenic Keratocysts in a Non-syndromic Young Patient: An Unusual Case Report

2021 ◽  
Vol 9 (01) ◽  
pp. 87-90
Author(s):  
Ravish Mishra ◽  
Laxmi Kandel ◽  
Deepak Yadav ◽  
Shashank Tripathi ◽  
Bijay Karki ◽  
...  
Keyword(s):  
High Recurrence Rate ◽  
Jaw Cysts ◽  
Dental Lamina ◽  
Odontogenic Keratocysts ◽  
Goltz Syndrome ◽  
Long Term Follow Up ◽  
Intraosseous Lesion ◽  
Unusual Case Report

Odontogenic keratocyst (OKC) is a benign intraosseous lesion with invasive and aggressive behavior. It comprises approximately 2-21.8% of all jaw cysts. Odontogenic keratocysts (OKCs) are believed to arise from remnants of the dental lamina most common site in the molar ramus area. OKCs have a specific histopathologic appearance and are found to be locally aggressive and have a high recurrence rate, thus requires close long-term follow-up. OKCs are one component of the Gorlin-Goltz syndrome and all patients with multiple OKCs should be evaluated for this syndrome. In this paper, we present a case of a 13-year old non-syndromic female patient with multiple OKCs located at symphysis and bilateral mandibular angle region who was treated surgically with no obvious post-operative complications during follow-up period.

scholarly journals Rare agressive form of giant-cell granuloma: a three years follow-up case report and discussion about medical therapeutic solutions

2018 ◽  
Vol 24 (4) ◽  
pp. 187-191
Author(s):  
Grégoire Huguet ◽  
Benoît Piot ◽  
Elisabeth Cassagnau ◽  
Jean-François Simon ◽  
Philippe Lesclous
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Surgical Approach ◽  
Gold Standard ◽  
Scientific Literature ◽  
Giant Cell Granuloma ◽  
Intralesional Injections ◽  
Intraosseous Lesion ◽  
Interesting Alternative

Introduction: Central giant cell granuloma (CGCG) is a rare and benign intraosseous lesion that usually occurs in the mandible and the maxilla. It might be aggressive. Nowadays, several treatments exist. Observation: This case report, with a three years follow-up, was about an aggressive and recurring form of CGCG exclusively managed by surgical approach. Comments: Several pharmacologic approaches are possible (intralesional injections of glucocorticoids, administration of calcitonin, alpha-2a interferon, denosumab) and could be an interesting alternative or complement to the surgical management when CGCG is aggressive, recurring, or non resectable. Conclusion: Surgical approach is the gold standard for the treatment of CGCG but sometimes, pharmacologic approaches could be proposed. According to the scientific literature, denosumab appears as a reliable and effective treatment but more prospective studies are needed.

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