scholarly journals Huntington's disease treatment with memantine prevented the progression of chorea movement

2021 ◽  
Author(s):  
Kazumasa Saigoh ◽  
Makito Hirano ◽  
Yoshiuki Mitsui ◽  
Ikegawa Atsuko ◽  
Itsuki Oda ◽  
...  
Keyword(s):  
Blood Flow ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Clinical Symptom ◽  
Temporal Lobe ◽  
Disease Treatment ◽  
Flow Image

We have recorded the Huntington’s disease patient’s gait videos at the5 years. It’s treatment with memantine prevented the progression of Clinical symptom. It is recognized to be improved blood flow image in front-temporal lobe of IMP-SPECT.

scholarly journals Reduced regional cerebral blood flow in Huntington's disease studied by SPECT.

1992 ◽  
Vol 55 (11) ◽  
pp. 1018-1023 ◽  
Author(s):  
S G Hasselbalch ◽  
G Oberg ◽  
S A Sorensen ◽  
A R Andersen ◽  
G Waldemar ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood

E08 Cerebral blood flow is associated with disease severity and cognitive defecits in pre/early huntington’s disease

2018 ◽  
Author(s):  
Hannah Furby ◽  
James Ralph ◽  
Anne E Rosser ◽  
Peter O’Callaghan ◽  
Kevin Murphy ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Disease Severity

scholarly journals Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Alejandro Lopez-Hurtado ◽  
Diego A. Peraza ◽  
Pilar Cercos ◽  
Laura Lagartera ◽  
Paz Gonzalez ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Small Molecules ◽  
Huntington’S Disease ◽  
Calcium Sensor ◽  
Disease Treatment ◽  
Neuronal Calcium Sensor

scholarly journals Diphenyl diselenide protects a Caenorhabditis elegans model for Huntington's disease by activation of the antioxidant pathway and a decrease in protein aggregation

Metallomics ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1142-1158
Author(s):  
Fabiane Bicca Obetine Baptista ◽  
Leticia Priscilla Arantes ◽  
Marina Lopes Machado ◽  
Aline Franzen da Silva ◽  
Larissa Marafiga Cordeiro ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Protein Misfolding ◽  
Nuclear Translocation ◽  
Oxygen Species ◽  
Diphenyl Diselenide ◽  
Disease Treatment ◽  
C Elegans ◽  
Superoxide Dismutase 3 ◽  
Protein Misfolding And Aggregation

The effect of (PhSe)2 in a C. elegans model for Huntington's disease. Treatment with (PhSe)2 triggered the nuclear translocation and activation of DAF-16 transcription factor in C. elegans, inducing the expression of superoxide dismutase-3 (SOD-3) and heat shock protein-16.2 (HSP-16.2). SOD-3 acts on reactive oxygen species (ROS) detoxification, and HSP-16.2 decreases protein misfolding and aggregation, which occur in HD.

Sign in / Sign up

Export Citation Format

Share Document