Cryptococcal Infection with Ruxolitinib in Primary Myelofibrosis: A Case Report and Literature Review

Cryptococcus neoformans (CN) is an encapsulated yeast that causes disseminated and potentially life-threatening in immunocompromised hosts. We present a patient with primary myelofibrosis on ruxolitinib who developed disseminated disease due to CN. The report underscores the importance of suspecting infections with intracellular pathogens in immunosuppressed patients on ruxolitinib.

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Cryptococcal infection of the colon in a patient without concurrent human immunodeficiency infection: a case report and literature review

European Journal of Clinical Microbiology & Infectious Diseases ◽

10.1007/s10096-021-04268-5 ◽

2021 ◽

Author(s):

Alvaro Quincho-Lopez ◽

Noah Kojima ◽

John M. Nesemann ◽

Rogger Verona-Rubio ◽

Dina Carayhua-Perez

Keyword(s):

Human Immunodeficiency Virus ◽

Literature Review ◽

Hiv Infection ◽

Chronic Diarrhea ◽

Cryptococcal Infection ◽

Pulmonary System ◽

Immunodeficiency Virus ◽

The Central Nervous System ◽

Disseminated Disease ◽

Histopathology Examination

AbstractCryptococcosis is a fungal infection that is rarely reported in patients without human immunodeficiency virus (HIV) infection, especially when the central nervous system (CNS) or pulmonary system is not involved. We report a case of isolated colonic cryptococcosis without disseminated disease in a 64-year-old immunocompetent woman without HIV infection who presented with chronic diarrhea and no episodes of fever or weight loss. The diagnosis was based on histopathology examination. Furthermore, we performed a literature review showing that few reports have been published so far and in the case of colonic cryptococcal infection, the prognosis is favorable among HIV-uninfected patients.

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Disseminated Nocardia beijingensis Infection in an Immunocompetent Patient

European Journal of Case Reports in Internal Medicine ◽

10.12890/2020_001904 ◽

2020 ◽

Author(s):

Moni Roy ◽

Annia Martial ◽

Sharjeel Ahmad

Keyword(s):

Literature Review ◽

Immunocompetent Patient ◽

Chest Ct ◽

Primary Site ◽

Immunocompetent Host ◽

Onset Seizure ◽

Pulmonary System ◽

Life Threatening ◽

Immunocompromised Hosts ◽

New Onset

Nocardia is a genus of aerobic, non-motile and non-spore-forming filamentous branching bacteria with fragmentation into bacillary or coccoid forms. Infections caused by Nocardia often occur in immunocompromised hosts and are potentially life-threatening. Nocardia beijingensis has rarely been reported to cause infection in immunocompetent hosts. We present a case of disseminated infection due to Nocardia beijingensis in a patient with no known medical comorbidities, who presented with new-onset seizure. Another interesting finding in our case is that our patient did not have any pulmonary symptoms despite chest CT showing the pulmonary system as the likely primary site of infection. As per our literature review, this is the seventh reported case of infection due to Nocardia beijingensis in an immunocompetent host.

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Life-threatening spontaneous splenic rupture with systemic lupus erythematosus: case report and literature review

Clinical Rheumatology ◽

10.1007/s10067-011-1934-8 ◽

2012 ◽

Vol 31 (6) ◽

pp. 1019-1025 ◽

Cited By ~ 5

Author(s):

Jie Han ◽

Ning Li ◽

JiaYi Wang ◽

JieRu Zhou ◽

Jie Zhang

Keyword(s):

Systemic Lupus Erythematosus ◽

Case Report ◽

Literature Review ◽

Lupus Erythematosus ◽

Splenic Rupture ◽

Spontaneous Splenic Rupture ◽

Systemic Lupus ◽

Systemic Lupus Erythematosus Case ◽

Life Threatening

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Cardiac tamponade as a late complication of a minor trauma due to syncope: A case report and literature review

Hong Kong Journal of Emergency Medicine ◽

10.1177/1024907918793790 ◽

2018 ◽

Vol 27 (2) ◽

pp. 103-106 ◽

Cited By ~ 1

Author(s):

Matteo Guarino ◽

Alessandra Bologna ◽

Alfredo De Giorgi ◽

Michele D Spampinato ◽

Christian Molino ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Cardiac Tamponade ◽

Blunt Chest Trauma ◽

Chest Trauma ◽

Late Complication ◽

Minor Trauma ◽

Threatening Condition ◽

Life Threatening ◽

A Minor

Haemopericardium with cardiac tamponade following minor blunt trauma is a rare, life-threatening condition. The diagnosis of cardiac tamponade as well as therapeutic management may be delayed, since the link between trauma and illness is often overlooked. We report the case of an old woman who developed a relatively delayed cardiac tamponade due to an otherwise minor blunt chest trauma following syncope.

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