scholarly journals Disseminated Nocardia beijingensis Infection in an Immunocompetent Patient

2020 ◽  
Author(s):  
Moni Roy ◽  
Annia Martial ◽  
Sharjeel Ahmad
Keyword(s):  
Literature Review ◽  
Immunocompetent Patient ◽  
Chest Ct ◽  
Primary Site ◽  
Immunocompetent Host ◽  
Onset Seizure ◽  
Pulmonary System ◽  
Life Threatening ◽  
Immunocompromised Hosts ◽  
New Onset

Nocardia is a genus of aerobic, non-motile and non-spore-forming filamentous branching bacteria with fragmentation into bacillary or coccoid forms. Infections caused by Nocardia often occur in immunocompromised hosts and are potentially life-threatening. Nocardia beijingensis has rarely been reported to cause infection in immunocompetent hosts. We present a case of disseminated infection due to Nocardia beijingensis in a patient with no known medical comorbidities, who presented with new-onset seizure. Another interesting finding in our case is that our patient did not have any pulmonary symptoms despite chest CT showing the pulmonary system as the likely primary site of infection. As per our literature review, this is the seventh reported case of infection due to Nocardia beijingensis in an immunocompetent host.

scholarly journals Cryptococcal Infection with Ruxolitinib in Primary Myelofibrosis: A Case Report and Literature Review

2021 ◽  
Author(s):  
Zachary Ciochetto ◽  
Njeri Wainaina ◽  
Anna Corey ◽  
Mary Beth Graham ◽  
Muhammad Bilal Abid
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cryptococcus Neoformans ◽  
Primary Myelofibrosis ◽  
Intracellular Pathogens ◽  
Cryptococcal Infection ◽  
Immunosuppressed Patients ◽  
Life Threatening ◽  
Disseminated Disease ◽  
Immunocompromised Hosts

Cryptococcus neoformans (CN) is an encapsulated yeast that causes disseminated and potentially life-threatening in immunocompromised hosts. We present a patient with primary myelofibrosis on ruxolitinib who developed disseminated disease due to CN. The report underscores the importance of suspecting infections with intracellular pathogens in immunosuppressed patients on ruxolitinib.

scholarly journals A cavitary pneumonia caused by leptotrichia species in an immunocompetent patient

2012 ◽  
Vol 4 (1) ◽  
pp. 24 ◽  
Author(s):  
Tze Shien Lo
Keyword(s):  
Immunocompetent Patient ◽  
Immunocompetent Host ◽  
Oral Flora ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Gram Negative Bacillus ◽  
Normal Human ◽  
Immunocompromised Hosts

<em>Leptotrichia species </em>(LS) is an anaerobic Gram negative bacillus in the <em>Bacteroidaceae</em> family and part of the normal human oral flora. It is rarely pathogenic, but occasionally causes diseases in immunocompromised hosts. I am reporting a case of cavitary pneumonia caused by LS in an immunocompetent host.

Aspergillus Infection in an Immunocompetent Host With Supravalvular Aortic Stenosis

2017 ◽  
Vol 11 (4) ◽  
pp. NP99-NP102 ◽  
Author(s):  
Sedigheh Saedi ◽  
Zahra Khajali ◽  
Azin Alizadehasl
Keyword(s):  
Aortic Stenosis ◽  
Left Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Immunocompetent Patient ◽  
Left Ventricular ◽  
Supravalvular Aortic Stenosis ◽  
Immunocompetent Host ◽  
Mycotic Pseudoaneurysm ◽  
Left Ventricular Outflow ◽  
Immunocompromised Hosts

Supravalvular aortic stenosis is the rarest form of left ventricular outflow tract obstruction. Aspergillus endocarditis is also rare and generally reported in immunocompromised hosts. Here we present a case of an immunocompetent patient with supravalvular aortic stenosis complicated by aortic mycotic pseudoaneurysm due to invasive aspergillosis.

scholarly journals Pulmonary Nocardiosis in an Immunocompetent Patient with Cystic Fibrosis

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Lucy Schoen ◽  
Jonathan D. Santoro ◽  
Carlos Milla ◽  
Sumit Bhargava
Keyword(s):  
Cystic Fibrosis ◽  
Pulmonary Disease ◽  
Bacterial Infections ◽  
Pulmonary Infection ◽  
Immunocompetent Patient ◽  
Primary Site ◽  
Optimal Treatment ◽  
Active Infection ◽  
Pulmonary Nocardiosis ◽  
Immunocompromised Hosts

Nocardiaspp. are bacteria of low virulence that cause infection classically in immunocompromised hosts with the lungs as the primary site of infection in the majority of cases. Patients with cystic fibrosis have pulmonary disease characterized by frequent and progressive bacterial infections. Reports ofNocardiaspp. isolation in CF are rare in the literature and may represent colonization or active infection, the significance and optimal treatment of which are unknown. We report the second case to date ofNocardia transvalensispulmonary infection in an immunocompetent patient with CF and the first in a child under the age of eighteen.

scholarly journals Isolated Pancreatic Tuberculosis Mimicking Malignancy in an Immunocompetent Host

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Pooja Raghavan ◽  
Dhyan Rajan
Keyword(s):  
Chronic Pancreatitis ◽  
Diagnostic Testing ◽  
Immunocompetent Patient ◽  
Pancreatic Abscess ◽  
Immunocompetent Host ◽  
Pancreatic Tuberculosis ◽  
Pancreatic Masses ◽  
High Prevalence ◽  
Immunocompromised Hosts

Despite the high prevalence of tuberculosis (TB) worldwide, pancreatic TB is rare. When present, pancreatic TB is frequently associated with miliary TB, often in immunocompromised hosts. Pancreatic TB may present as a pancreatic abscess, acute or chronic pancreatitis, and cystic or solid pancreatic masses. We present a case of an immunocompetent patient who presented with two discrete pancreatic masses and was subsequently diagnosed with isolated pancreatic TB. This case suggests that clinicians should have a heightened suspicion of pancreatic TB when faced with discrete pancreatic lesions, especially in patients from areas where the infection is endemic. Such recognition may lead to appropriate diagnostic testing, and possible resolution of pancreatic lesions with antituberculin therapy.

scholarly journals New-Onset Seizure With Possible Limbic Encephalitis in a Patient With COVID-19 Infection: A Case Report and Review

2021 ◽  
Vol 9 ◽  
pp. 232470962098630
Author(s):  
Riwaj Bhagat ◽  
Barbara Kwiecinska ◽  
Nolan Smith ◽  
Matthew Peters ◽  
Christopher Shafer ◽  
...  
Keyword(s):  
Brain Magnetic Resonance Imaging ◽  
Nasopharyngeal Swab ◽  
Onset Seizure ◽  
Cerebrospinal Fluid Analysis ◽  
Fluid Analysis ◽  
Global Pandemic ◽  
Elevated Protein ◽  
T2 Hyperintensity ◽  
Elevated Protein Level ◽  
New Onset

With the outbreak of COVID-19 (coronavirus disease 2019) as a global pandemic, various of its neurological manifestations have been reported. We report a case of a 54-year-old male with new-onset seizure who tested positive for severe acute respiratory syndrome coronavirus 2 from a nasopharyngeal swab sample. Investigative findings, which included contrast-enhancing right posterior temporal lobe T2-hyperintensity on brain magnetic resonance imaging, right-sided lateralized periodic discharges on the electroencephalogram, and elevated protein level on cerebrospinal fluid analysis, supported the diagnosis of possible encephalitis from COVID-19 infection. The findings in this case are placed in the context of the existing literature.

scholarly journals Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease

2021 ◽  
Author(s):  
Esfandiar Shojaei ◽  
Joanna C Walsh ◽  
Nikhil Sangle ◽  
Brian Yan ◽  
Michael S Silverman ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Antifungal Therapy ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Disseminated Histoplasmosis ◽  
Gastrointestinal Histoplasmosis ◽  
Life Threatening ◽  
Inflammatory Drugs ◽  
Tissue Specimens

Abstract Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed as biopsy-proven Crohn’s disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his GI illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn’s disease.

scholarly journals Cryptococcal infection of the colon in a patient without concurrent human immunodeficiency infection: a case report and literature review

2021 ◽  
Author(s):  
Alvaro Quincho-Lopez ◽  
Noah Kojima ◽  
John M. Nesemann ◽  
Rogger Verona-Rubio ◽  
Dina Carayhua-Perez
Keyword(s):  
Human Immunodeficiency Virus ◽  
Literature Review ◽  
Hiv Infection ◽  
Chronic Diarrhea ◽  
Cryptococcal Infection ◽  
Pulmonary System ◽  
Immunodeficiency Virus ◽  
The Central Nervous System ◽  
Disseminated Disease ◽  
Histopathology Examination

AbstractCryptococcosis is a fungal infection that is rarely reported in patients without human immunodeficiency virus (HIV) infection, especially when the central nervous system (CNS) or pulmonary system is not involved. We report a case of isolated colonic cryptococcosis without disseminated disease in a 64-year-old immunocompetent woman without HIV infection who presented with chronic diarrhea and no episodes of fever or weight loss. The diagnosis was based on histopathology examination. Furthermore, we performed a literature review showing that few reports have been published so far and in the case of colonic cryptococcal infection, the prognosis is favorable among HIV-uninfected patients.

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