scholarly journals EPIDEMIOLOGICAL FEATURES AND EVOLUTION OF CLINICAL PRESENTATION OF TYPHOID FEVER IN SAINT-PETERSBURG

2019 ◽  
Vol 11 (1) ◽  
pp. 25-32
Author(s):  
K. E. Novak ◽  
A. G. Dyachkov ◽  
E. V. Esaulenko
Keyword(s):  
Infectious Diseases ◽  
Typhoid Fever ◽  
Clinical Presentation ◽  
Homeless People ◽  
Atypical Form ◽  
Saint Petersburg ◽  
Epidemiological Features ◽  
Number Of Patients ◽  
Atypical Clinical Presentation ◽  
Changes Over Time

Purpose: To study an epidemiological features and evolution of clinical presentation of typhoid fever in modern megapolisMaterials and methods: A study of 115 patient’s medical records was performed. All patients were hospitalized in Clinical Infectious Diseases Hospital named after S.P. Botkin, Saint-Petersburg, Russia during 2005–2017 with confirmed diag№sis of typhoid fever. We have conducted a comparison of epidemiological and clinical features between 59 patients hospitalized in 2005–2009 and 56 hospitalized in 2010–2017.Results: There was increase proportion of Central Asia’ countries citizens among study group during recent years. Social status of affected patients had also changed recently due to decrease fraction of homeless people along with decreased number of patients with accompanied infectious diseases. Atypical clinical presentation had become more common №wadays with most of a patients presented with moderate severity form of disease.Conclusion: Clinical presentation and epidemiology of typhoid fever are prone to changes over time. New data on epidemiology and predominance of atypical form of disease need to be considered to ensure prompt diag№sis of a disease.

scholarly journals CONGENITAL CARDITIS IN A NEWBORN (case report)

2019 ◽  
Vol 6 (1) ◽  
pp. 24-31
Author(s):  
M.O. Gonchar ◽  
A.V. Senatorova ◽  
N.K. Matsievskaya ◽  
D.V. Zatoloka
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Infectious Diseases ◽  
Diagnostic Criteria ◽  
Clinical Presentation ◽  
Clinical Manifestations ◽  
Intrauterine Infection ◽  
High Technology ◽  
Technology Research ◽  
Atypical Clinical Presentation

CONGENITAL CARDITIS IN A NEWBORN (case report)Gonchar M.O., Senatorova A.V., Matsiyevskaya N.K., Zatoloka D.V.Diagnosis of carditis in newborns presents a number of difficulties, even with the results of high-technology research methods. Carditis is characterized by the absence of specific diagnostic criteria, similarity of clinical manifestations of cardiovascular and respiratory failure in young children, including secondary to generalized infectious diseases. The article presents a case of an atypical clinical presentation of carditis in a child with a confirmed intrauterine infection.Key words: newborns, carditis, intrauterine infection ВРОДЖЕНИЙ КАРДИТ У НОВОНАРОДЖЕНОГО (клінічне спостереження)Гончар М.О., Сенаторова А.В., Мацієвська Н.К., Затолока Д.В.Встановлення діагнозу кардит у новонароджених має ряд труднощів, навіть при наявності результатів високотехнологічних методів дослідження. Кардит характеризується відсутністю специфічних діагностичних критеріїв, схожістю клінічних проявів серцево-судинної і дихальної недостатності у дітей раннього віку, в тому числі на тлі генералізованої інфекційної патології. У статті представлений випадок нетипового клінічного перебігу розвитку кардиту у дитини з підтвердженою внутрішньоутробною інфекцією.Ключові слова: новонароджені, кардит, внутрішньоутробна інфекція ВРОЖДЕННЫЙ КАРДИТ У НОВОРОЖДЕННОГО (клиническое наблюдение)Гончарь М.О., Сенаторова А.В., Мациевская Н.К., Затолока Д.В.Установление диагноза кардит у новорождённых имеет ряд сложностей, даже при наличие  результатов высокотехнологических методов исследования. Кардит характеризуется отсутствием специфических диагностических критериев, сходством клинических проявлений сердечно-сосудистой и дыхательной недостаточности у детей раннего возраста, в том числе на фоне генерализованной инфекционной патологии. В статье представлен случай нетипичного клинического течения развития кардита у ребенка с подтвержденной внутриутробной инфекцией.Ключевые слова: новорожденные, кардит, внутриутробная инфекция  

Computer-Aided Diagnosis in Jaundice: Comparison of Knowledge-based and Probabilistic Approaches

1996 ◽  
Vol 35 (01) ◽  
pp. 41-51 ◽  
Author(s):  
F. Molino ◽  
D. Furia ◽  
F. Bar ◽  
S. Battista ◽  
N. Cappello ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Information ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Clinical Documentation ◽  
Data Set ◽  
Knowledge Based ◽  
Number Of Patients ◽  
Support Tools ◽  
Aided Diagnosis

AbstractThe study reported in this paper is aimed at evaluating the effectiveness of a knowledge-based expert system (ICTERUS) in diagnosing jaundiced patients, compared with a statistical system based on probabilistic concepts (TRIAL). The performances of both systems have been evaluated using the same set of data in the same number of patients. Both systems are spin-off products of the European project Euricterus, an EC-COMACBME Project designed to document the occurrence and diagnostic value of clinical findings in the clinical presentation of jaundice in Europe, and have been developed as decision-making tools for the identification of the cause of jaundice based only on clinical information and routine investigations. Two groups of jaundiced patients were studied, including 500 (retrospective sample) and 100 (prospective sample) subjects, respectively. All patients were independently submitted to both decision-support tools. The input of both systems was the data set agreed within the Euricterus Project. The performances of both systems were evaluated with respect to the reference diagnoses provided by experts on the basis of the full clinical documentation. Results indicate that both systems are clinically reliable, although the diagnostic prediction provided by the knowledge-based approach is slightly better.

scholarly journals Is Call Karma Real? Resident After-Hours On-Call Imaging at the University of Saskatchewan: An Assessment of Call Volumes Including Inter-Resident Variability

2021 ◽  
pp. 084653712110263
Author(s):  
James Huynh ◽  
David Horne ◽  
Rhonda Bryce ◽  
David A Leswick
Keyword(s):  
Mean Shift ◽  
Mean Values ◽  
Body Regions ◽  
Time Period ◽  
Relative Value ◽  
Number Of Patients ◽  
After Hours ◽  
Disproportionate Number ◽  
The University ◽  
Changes Over Time

Purpose: Quantify resident caseload during call and determine if there are consistent differences in call volumes for individuals or resident subgroups. Methods: Accession codes for after-hours computed tomography (CT) cases dictated by residents between July 1, 2012 and January 9, 2017 were reviewed. Case volumes by patient visits and body regions scanned were determined and categorized according to time period, year, and individual resident. Mean shift Relative Value Units (RVUs) were calculated by year. Descriptive statistics, linear mixed modeling, and linear regression determined mean values, differences between residents, associations between independent variables and outcomes, and changes over time. Consistent differences between residents were assessed as a measure of good or bad luck / karma on call. Results: During this time there were 23,032 patients and 30,766 anatomic regions scanned during 1,652 call shifts among 32 residents. Over the whole period, there were on average 10.6 patients and 14.3 body regions scanned on weekday shifts and 22.3 patients and 29.4 body regions scanned during weekend shifts. Annually, the mean number of patients, body regions, and RVUs scanned per shift increased by an average of 0.2 (1%), 0.4 (2%), and 1.2 (5%) (all p < 0.05) respectively in regression models. There was variability in call experiences, but only 1 resident had a disproportionate number of higher volume calls and fewer lower volume shifts than expected. Conclusions: Annual increases in scan volumes were modest. Although residents’ experiences varied, little of this was attributable to consistent personal differences, including luck or call karma.

scholarly journals Atypical Clinical Presentation of Laryngopharyngeal Reflux: A 5-Year Case Series

2021 ◽  
Vol 10 (11) ◽  
pp. 2439
Author(s):  
Jerome R. Lechien ◽  
Stéphane Hans ◽  
Francois Bobin ◽  
Christian Calvo-Henriquez ◽  
Sven Saussez ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Laryngopharyngeal Reflux ◽  
Case Series ◽  
Clinical Findings ◽  
Aerodigestive Tract ◽  
Common Disease ◽  
Upper Aerodigestive Tract ◽  
Suppurative Otitis Media ◽  
Adequate Treatment ◽  
Atypical Clinical Presentation

Background: Laryngopharyngeal reflux (LPR) is a common disease in otolaryngology characterized by an inflammatory reaction of the mucosa of the upper aerodigestive tract caused by digestive refluxate enzymes. LPR has been identified as the etiological or favoring factor of laryngeal, oral, sinonasal, or otological diseases. In this case series, we reported the atypical clinical presentation of LPR in patients presenting in our clinic with reflux. Methods: A retrospective medical chart review of 351 patients with LPR treated in the European Reflux Clinic in Brussels, Poitiers and Paris was performed. In order to be included, patients had to report an atypical clinical presentation of LPR, consisting of symptoms or findings that are not described in the reflux symptom score and reflux sign assessment. The LPR diagnosis was confirmed with a 24 h hypopharyngeal-esophageal impedance pH study, and patients were treated with a combination of diet, proton pump inhibitors, and alginates. The atypical symptoms or findings had to be resolved from pre- to posttreatment. Results: From 2017 to 2021, 21 patients with atypical LPR were treated in our center. The clinical presentation consisted of recurrent aphthosis or burning mouth (N = 9), recurrent burps and abdominal disorders (N = 2), posterior nasal obstruction (N = 2), recurrent acute suppurative otitis media (N = 2), severe vocal fold dysplasia (N = 2), and recurrent acute rhinopharyngitis (N = 1), tearing (N = 1), aspirations (N = 1), or tracheobronchitis (N = 1). Abnormal upper aerodigestive tract reflux events were identified in all of these patients. Atypical clinical findings resolved and did not recur after an adequate antireflux treatment. Conclusion: LPR may present with various clinical presentations, including mouth, eye, tracheobronchial, nasal, or laryngeal findings, which may all regress with adequate treatment. Future studies are needed to better specify the relationship between LPR and these atypical findings through analyses identifying gastroduodenal enzymes in the inflamed tissue.

Minor liver failure

1930 ◽  
Vol 26 (11) ◽  
pp. 1088-1091
Author(s):  
- Tutkovsky
Keyword(s):  
Infectious Diseases ◽  
Typhoid Fever ◽  
Liver Failure

Small liver failure, which the British call "torpid liver", and Carriere calls "petit hepatisme", can be, especially in the initial stages, a purely transient moment: it is found in infectious diseases (typhoid fever, dysentery, flu), then it can be observed during attacks of hepatic colic, or after them, sometimes this insufficiency is noted with catarrhal jaundice.Liver failure is noted with chloroform anesthesia, with some transient poisoning, especially arsenic.It is observed in persons with a weak liver inherited, it happens quite often in children, as well as in women, during pregnancy.

Intradermal reaction with typhoid fever

1927 ◽  
Vol 23 (12) ◽  
pp. 1288-1288
Keyword(s):  
Typhoid Fever ◽  
Intradermal Test ◽  
Number Of Patients ◽  
Technical Simplicity ◽  
Typhoid Toxin

Having applied an intradermal test with typhoid toxin in a significant number of patients suffering from both typhoid fever and other acute febrile illnesses, Alisov and Morozkin came to the conclusion that this reaction is diagnostically equivalent to Widala's reaction, surpassing the latter in the speed of detection and greater technical simplicity.

Epidemiological features of typhoid fever incidence in the uranium biogeochemical zone of the Kyrgyz Republic

2020 ◽  
pp. 8-17
Author(s):  
R. M. Toichuev ◽  
J. S. Zakirova ◽  
S. T. Joldoshev ◽  
R. A. Nadirbekova
Keyword(s):  
Typhoid Fever ◽  
Kyrgyz Republic ◽  
Immunological Reactivity ◽  
Complete Elimination ◽  
Radiation Factor ◽  
Environmental Objects ◽  
Epidemiological Features ◽  
Sources Of Infection ◽  
Clean Drinking Water ◽  
The Impact

The results of an epidemiological study of typhoid fever in the territory of the uranium biogeochemical zone of the Kyrgyz Republic are presented. The presence of a chronic focus of typhoid fever in the territory of the uranium biogeochemical province with high levels of morbidity has been established. The leading factor in transmission is water, primarily from the Mailuu-Suu river, which is also contaminated with radionuclides. The main feature of typhoid fever in the territory of the uranium biogeochemical province is the registration of cases of diseases throughout the year, which differs from non-polluted areas, where cases are detected only in the warm months. This feature can be associated with the impact of the radiation factor on the pathogen by increasing its resistance, and on the human body by reducing immunological reactivity. This assumption requires more detailed research. For the complete elimination of typhoid fever in the study area, comprehensive measures are required throughout the year, aimed at providing the population with clean drinking water, identifying sources of infection, including bacterial carriers, and their treatment, as well as monitoring bacteriological studies of environmental objects throughout the calendar year.

scholarly journals A Case of Malaria Predisposing to Salmonella Bacteremia in a Returning Traveler from Nigeria

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Robert Jakubowski ◽  
Lisa L. Steed ◽  
Susan E. Dorman ◽  
Camelia Marculescu
Keyword(s):  
Infectious Diseases ◽  
Typhoid Fever ◽  
Blood Cultures ◽  
Antigen Testing ◽  
The U.S

We describe a febrile adult returning to the U.S. from Nigeria. Malaria was diagnosed by rapid antigen testing, but recognition of invasive nontyphoidal Salmonella disease was delayed. While the moniker, “typhomalaria,” once used to describe an illness with features of malaria and typhoid fever, has fallen out of favor, it may nevertheless be a helpful reminder to clinicians that both infectious diseases can arise in the same patient. Blood cultures should be obtained routinely in febrile returning travelers from malaria-endemic regions, including those in whom the diagnosis of malaria has already been established.

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