scholarly journals Implementation of 3D-CT based brachytherapy in the postoperative radiotherapy of cervical cancer: Treatment technique and dose-volume parameters

2009 ◽  
Vol 56 (4) ◽  
pp. 201-207
Author(s):  
V. Plesinac-Karapandzic ◽  
N. Borojevic ◽  
B. Markovic ◽  
V. Stankovic ◽  
S. Vuckovic ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
At Risk ◽  
Cancer Treatment ◽  
Postoperative Radiotherapy ◽  
Reference Points ◽  
Intracavitary Brachytherapy ◽  
Treatment Technique ◽  
3D Ct ◽  
Dose Volume ◽  
Organ At Risk

Intracavitary brachytherapy has an important roll in developing complications in postoperative radiotherapy of cervical cancer. 3D-CT based brachytherapy gives precisely estimating doses to organ at risk. In this study, we show our preliminary results in implementation of 3D-imaging based postoperative brachytherapy of cervical cancer: treatment technique and dose-volume parameters. During 2009 year, in 6 patients with early stage I-II of cervical cancer, brachytherapy treatment planning was based on the radiographs and CT imaging brachytherapy technique. Mean values of ICRU reference points of rectum was R max 4,2Gy and bladder B max. 4,5Gy, while estimated volume-dose parameters D0.1 cm 3 D1.0 cm 3 D2.0 cm 3 were presented with higher dose. Volume of organ at risk reflected the need for better bladder preparation. Our initial experience in performing CT-based brachytherapy, enabled us to introduce the characteristics of the parameters, assessment of their significance from the aspect of mutual relations applicators and organs at risk. Further analysis are needed, for monitoring the effects of 3D planning on complications.

UK audit of target volume and organ at risk delineation and dose optimisation for cervix radiotherapy treatments

2020 ◽  
Vol 93 (1110) ◽  
pp. 20190897
Author(s):  
Jennifer Cannon ◽  
Peter Bownes ◽  
Joshua Mason ◽  
Rachel Cooper
Keyword(s):  
Cervical Cancer ◽  
At Risk ◽  
Planning Target Volume ◽  
Treatment Plan ◽  
Target Volume ◽  
Dose Fractionation ◽  
Treatment Technique ◽  
Dose Optimisation ◽  
Treatment Plans ◽  
Organ At Risk

Objective: Assessment of the extent of variation in delineations and dose optimisation performed at multiple UK centres as a result of interobserver variation and protocol differences. Methods: CT/MR images of 2 cervical cancer patients previously treated with external beam radiotherapy (EBRT) and Brachytherapy were distributed to 11 UK centres. Centres delineated structures and produced treatment plans following their local protocol. Organ at risk delineations were assessed dosimetrically through application of the original treatment plan and target volume delineations were assessed in terms of variation in absolute volume and length, width and height. Treatment plan variation was assessed across all centres and across centres that followed EMBRACE II. Treatment plans were assessed using total EQD2 delivered and were compared to EMBRACE II dose aims. Variation in combined intracavitary/interstitial brachytherapy treatments was also assessed. Results: Brachytherapy target volume delineations contained variation due to differences in protocol used, window/level technique and differences in interpretations of grey zones. Planning target volume delineations were varied due to protocol differences and extended parametrial tissue inclusion. All centres met EMBRACE II plan aims for PTV V95 and high-riskclinical target volume D90 EQD2, despite variation in prescription dose, fractionation and treatment technique. Conclusion: Brachytherapy target volume delineations are varied due to differences in contouring guidelines and protocols used. Planning target volume delineations are varied due to the uncertainties surrounding the extent of parametrial involvement. Dosimetric optimisation is sufficient across all centres to satisfy EMBRACE II planning aims despite significant variation in protocols used. Advances in knowledge: Previous multi-institutional audits of cervical cancer radiotherapy practices have been performed in Europe and the USA. This study is the first of its kind to be performed in the UK.

scholarly journals Evaluation of Organ at Risk (OAR) Doses based on 2D Treatment Planning in Intracavitary Brachytherapy of Cervical Cancer

2015 ◽  
Vol 44 (8) ◽  
pp. 1145-1151 ◽  
Author(s):  
Reduan Abdullah ◽  
Nur Aqilah Abdul Sani ◽  
Suk Chiang Chen ◽  
Mazurawati Mohamed ◽  
Nik Ruzman Nik Idris ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
At Risk ◽  
Treatment Planning ◽  
Intracavitary Brachytherapy ◽  
Organ At Risk

PO-245 EFFECT OF BLADDER DISTENSION ON DOSIMETRY OF ORGAN AT RISK IN CT BASED PLANNING OF HDR ICBT FOR CERVICAL CANCER

2012 ◽  
Vol 103 ◽  
pp. S99
Author(s):  
K. Sazzad Manir ◽  
P. Niladri B ◽  
B. Swapnendu ◽  
G. Jyotirup ◽  
K. Apurba K ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
At Risk ◽  
Bladder Distension ◽  
Organ At Risk
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