scholarly journals Association of a large vulvar tumor in a in a young premenopausal woman with recurrent pseudoangiomatous stromal hyperplasia of the breasts

2020 ◽  
Vol 26 (1) ◽  
pp. 16-18
Author(s):  
Angelica Knickerbocker ◽  
Douglas Timmons ◽  
Youley Tjendra ◽  
Simone Garzon ◽  
Jose Carugno

Pseudoangiomatous stromal hyperplasia is a benign proliferative lesion of the breast tissue that typically affects women in the reproductive age. Pseudoangiomatous stromal hyperplasia usually presents as a localized, painless, firm mass or as a diffuse thickened area of the breast. Rarely, it can arise along the embryonic milk line, up to the anogenital region, where it simulates angiosarcomas. Awareness of this uncommon condition is important in order to avoid unnecessary aggressive excisional surgical procedures. For this purpose, we present a case of nodular pseudoangiomatous stromal hyperplasia arising in the vulva in a patient with recurrent pseudoangiomatous stromal hyperplasia of the breast.

2020 ◽  
Vol 2 (2) ◽  
pp. 01-02
Author(s):  
Patrícia Couto

The pelvic endometriosis is considered a relatively common, benign, estrogen-dependent disease associated with complaints of pelvic pain and infertility, affecting 6% to 10% of women of reproductive age. The etiopathogenesis of the disease is based on some theories and hypotheses. Classical theories include the hypothesis of migratory pathogenesis by retrograde menstrual flow, the theory of celomic metaplasia, the theory of embryonic rest or even iatrogenic deposition during abdominal surgical procedures


2013 ◽  
Vol 45 (4) ◽  
pp. 235-236
Author(s):  
H.-F. Selig ◽  
E. Bareck ◽  
L. Michlmayer ◽  
S. Halper ◽  
F. Längle ◽  
...  

2010 ◽  
Vol 134 (7) ◽  
pp. 1070-1074 ◽  
Author(s):  
Renu K. Virk ◽  
Ashraf Khan

Abstract Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign, proliferative mesenchymal lesion with possible hormonal etiology. It typically affects women in the reproductive age group. Pseudoangiomatous stromal hyperplasia is frequently an incidental histologic finding in breast biopsies performed for other benign or malignant lesions. Rarely, it can present as a firm, painless breast mass, which has been referred to as nodular or tumorous PASH. Grossly, tumorous PASH is a well-circumscribed, firm, rubbery mass with solid, homogenous, gray-white cut surface. On histologic examination, it is characterized by the presence of open slitlike spaces in dense collagenous stroma. The spaces are lined by a discontinuous layer of flat, spindle-shaped myofibroblasts with bland nuclei. The spindle cells express progesterone receptors and are positive for vimentin, actin, and CD34. The most important differential diagnosis on histopathology is angiosarcoma. Pseudoangiomatous stromal hyperplasia discovered incidentally does not require any additional specific treatment. Tumorous PASH is treated by local surgical excision with clear margins and the prognosis is excellent, with minimal risk of recurrence after adequate surgical excision.


2009 ◽  
Vol 17 (3) ◽  
pp. 89-96 ◽  
Author(s):  
Walter Peters ◽  
Victor Fornasier

Fewer surgical procedures have a history as fascinating and as terrifying as breast augmentation. Initial efforts at augmentation involved injection of substances such as paraffin or oil into the breast tissue, or the implantation of substances including ivory or glass balls, or rubber. More recent efforts have included the injection of liquid silicone or polyacrylamide hydrogel. The current paper reviews four distinct eras of breast augmentation, and provides the current status of these injection materials. A case report is presented on a woman whose breasts were injected with polyacrylamide hydrogel in Iran. The current status of this group of materials is also presented. During the past 110 years, history has repeated itself during each of the four eras of injection.


2017 ◽  
Vol 4 (8) ◽  
pp. 2854
Author(s):  
Vasuki R. ◽  
Thanmaran N. B. ◽  
A. K. Kalpana Devi ◽  
Rajesh Menon Moothedath ◽  
Satheesh Kumar M.

Tumor-forming Pseudoangiomatous stromal hyperplasia (PASH) is a rather uncommon breast lesion and only very few cases of tumor-forming PASH were reported from 1986, since the lesion was originally described. In contrast, focal, non-tumor forming PASH may be an incidental microscopic finding in up to 23% of breast biopsies. PASH is a benign proliferative lesion of the breast stroma that is characterized by slit-like pseudovascular spaces lined by endothelial-like spindle cells. It is indeed rare for a discrete breast mass to have PASH as the main pathological feature on histopathology. The breast mass, typically unilateral, was usually diagnosed clinically as a fibroadenoma.When found in tumour form, PASH most commonly manifests as a single, circumscribed, palpable mass in a premenopausal female. The main differential diagnosis histologically are fibroadenoma, phyllodes tumor and angiosarcoma. However, PASH is a benign condition with very good prognosis. Hence possibility of PASH in nodular or tumour form has to be considered when approaching a case of breast lump whose management is different. We report here a case of PASH in tumour form from our Institute.


2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Sakinah A. Thiryayi ◽  
Marjan Rouzbahman ◽  
Danny Ghazarian

Mammary-like glands (MLG) are considered to be a normal constituent of the anogenital region and can give rise to tumors with variable morphology that may be difficult to classify. We present a case of an anogenital mammary-like gland tumor in a breastfeeding woman showing morphological variation with lactational change, an unusual finding. We discuss the differing terminology used to report these tumors and the variation in assignment of their origin to MLG or ectopic breast tissue.


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