scholarly journals Left atrial size in patients with arterial hypertension

2006 ◽  
Vol 134 (3-4) ◽  
pp. 100-105 ◽  
Author(s):  
Suzana Milutinovic ◽  
Svetlana Apostolovic ◽  
Ivan Tasic

INTRODUCTION Left atrial size is increased in patients with arterial hypertension. Left atrial enlargement represents a risk factor of atrial fibrillation and stroke. Left atrial size depends on the effect of many other etiological factors, predominantly by body mass and the left ventricular mass. OBJECTIVE The objective of the study was to investigate the frequency of the left atrial enlargement in patients with arterial hypertension, in obese patients with arterial hypertension and in patients with arterial hypertension and left ventricular hypertrophy. In addition, the aim was to investigate the influence of diastolic function parameters on the left atrial dimension. METHOD The study included 93 patients with arterial hypertension (mean age of 46.9 ? 9.7 years, 50.5% of males) and 33 healthy subjects (mean age 45.6 ?10.6 yrs., 40% of males) who consisted the control group. There was no statistical difference of the age and sex between patients and healthy persons. All patients were examined by the echocardiographic ultrasound device HP Sonos 2500 by three echosonographers. RESULTS The patients with arterial hypertension compared to the control group had significantly higher: body mass index (27.8 ? 4.1 versus 24.3 ? 3.0) (p<0.001), the left ventricular mass (249.7 ? 79.1 versus 174.6 ? 47.7) (p<0,001), the left ventricular mass index (122.2 ? 34.3 versus 96.7 + 20.9)(p<0.001) and the left atrium (3.8 ? 0.7 versus 3.3 ? 0.5) (p<0.001). The frequency of the left atrial enlargement in patients with arterial hypertension was 44.1%. The frequency of the left atrial enlargement In patients with arterial hypertension and the left ventricular hypertrophy was 53.3%, and in obese patients with arterial hypertension was 58.3%. Left ventricular diastolic function parameters in patients with arterial hypertension in relation to control exhibited statistically significant differences: isovolumetric relaxation time (IVRT) was longer (193.2 ? 37.8 versus 175,8 ? 23,6) (p<0.001), deceleration time (DT) was longer (193.2 ?37,8 versus 175.8 ?23.6) (p<0.01) and peak early diastolic filling wave velocity /peak atrial diastolic filling wave velocity ratio (E/A ratio) was lower (1.0 ? 0.3 versus 1.2 ? 0.3) (p<0.01). The quotient of linear correlation of the left ventricular diastolic function parameters in patients with arterial hypertension with left atrial volume did not show any significant correlation. CONCLUSION The left atrial size was statistically bigger in patients with arterial hypertension in relation to healthy subjects. The biggest left atrial enlargement was in hypertensive patients with the left ventricular hypertrophy and obese hypertensive patients. Left ventricular diastolic function parameters in patients with arterial hypertension had no statistically significant influence on the left atrial size.

2017 ◽  
Vol 2 (2) ◽  
pp. 21-25
Author(s):  
Kartikesh Kumar Thakur ◽  
Ratna Mani Gajurel ◽  
Sheelendra Shakya ◽  
Aseem Bhattarai ◽  
Mithileshwor Raut ◽  
...  

Background: This study was conducted with the objective of evaluation of the occurrence of left atrial enlargement (LAE) in hypertensive patients and its relationship with left ventricular mass index (LVMI).Methods: This single centre study was carried out at the Manmohan Cardiothoracic Vascular and Transplant Center, where total of 99 patients with hypertension who had left ventricular hypertrophy on echocardiography defined by left ventricular septal wall thickness > 9mm for female and >10 mm for male, were selected  from May 2015 to August 2015.Results: In the study, the left atrium was enlarged in 31% of the selected patients. A total of 44% of patients having left atrial enlargement had increased left ventricular mass index as well, while a positive correlation (r = 0.3) was observed between the left atrial size and the left ventricular mass index (p= 0.001). The mean Left Ventricular Mass Index was 98 ± 32.7 g/m2 as compared to 115.34 ± 40.2 in patients with left atrial enlargement. The mean systolic blood pressure with left atrial enlargement was 146.70 ± 21.64 g/m2. Out of 99 patients, 80% of patients with left atrial enlargement had elevated body mass indexes, 48% had a history of smoking, 32% had diabetes mellitus, 22% had other complications of hypertension, and 12% had dyslipidemia.Conclusions: We concluded that the Left Atrial Size correlates significantly with the Left Ventricular Mass Index. In addition, the presence of left atrial enlargement should raise the suspicion of other metabolic derangements in hypertensive patients.Ann. Clin. Chem. Lab. Med. 2016:2(2);21-25


2019 ◽  
Vol 36 (10) ◽  
pp. 1806-1813 ◽  
Author(s):  
Ana Teresa Timóteo ◽  
Luisa Moura Branco ◽  
Frederico Filipe ◽  
Ana Galrinho ◽  
Pedro Rio ◽  
...  

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