AbstractField surveys carried out within the upper Kızılırmak region have shown that the natural route-ways passing through the area have connected central Anatolia to eastern Anatolia throughout the ages. The route from north-central Anatolia reaches the Kızılırmak river by passing through the plains of Çekerek, Yıldızeli and Yıldız. The Kızılırmak river can be crossed on horseback where the road ends. A second route connects south-central Anatolia to Sivas by passing through the plains of Gemerek and Şarkışla, and leads to eastern Anatolia by passing through the Kızılırmak valley after Sivas. A third route reaches Altınyayla by passing through the Kızılırmak valley, the Şarkışla plain and reaches the plain of Malatya by travelling through a pass of the Kulmaç mountains running along the Balıklıtohma valley. A fourth route connects Sivas with Malatya via Taşlıdere, Ulaş, Kangal and Alacahan. Fieldwork has shown that these routes have been almost continuously used since the middle of the third millennium BC.