Two cases of the lymph duct type sporotrichosis in which itraconazole internal use was effective.

1995 ◽  
Vol 57 (2) ◽  
pp. 379-381 ◽  
Author(s):  
KYOKO MATSUURA
Keyword(s):  
Lymph Duct

CLINICAL CASE OF A MALIGNANT PECOMA OF THE LUNG

2019 ◽  
Vol 65 (5) ◽  
pp. 756-759
Author(s):  
Mikhail Postolov ◽  
Nadezhda Kovalenko ◽  
K. Babina ◽  
Stanislav Panin ◽  
Yelena Levchenko ◽  
...  
Keyword(s):  
Good Condition ◽  
Lung Neoplasm ◽  
Rare Condition ◽  
Epithelioid Cell ◽  
X Ray ◽  
Perivascular Epithelioid Cell ◽  
Mesenchymal Neoplasm ◽  
Preoperative Ct ◽  
Lymph Duct ◽  
The Right

Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm characterized by expression of both mela-nocytic and smooth muscle markers. Only 10 primary malignant lung PEComas have been reported up to date. We report a 59-year-old male who presented with a lung neoplasm, found during the routine X-ray examination. Preoperative CT-scan revealed the 3,5-cm-sized mass, located at the border of the upper, middle and lower lobes of the right lung. Patient underwent a thoracotomy, resection of the upper, middle and lower lobes of the right lung accompanied with mediastinal lymphadenectomy. After surgery, chylothorax was revealed. Conservative treatment was unsuccessful, so we performed laparoscopic clipping of the thoracic lymph duct. Patient was dismissed from hospital on the 10-th day after the second operation in good condition. In this report, we intend to increase the limited knowledge relating to natural history and optimal treatment of such a rare condition as a primary malignant lung PEComa.

Thoracic Lymph Duct Catheterization with a Venous Shunt in the Nonhuman Primate

2021 ◽  
pp. 1-9
Author(s):  
Jon Ehrmann ◽  
Claudia Generaux ◽  
Sharon Ostergaard ◽  
Wendy Johnson ◽  
Anne Rose ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Venous Shunt ◽  
Lymph Duct

Ezetimibe Inhibits Lymphatic Transport of Esterified Cholesterol but Not Free Cholesterol in Thoracic Lymph Duct-Cannulated Rats

2012 ◽  
Vol 26 (5) ◽  
pp. 427-431 ◽  
Author(s):  
Bungo Shirouchi ◽  
Yuri Nakamura ◽  
Yumiko Furukawa ◽  
Aya Shiraishi ◽  
Hiroko Tomoyori ◽  
...  
Keyword(s):  
Free Cholesterol ◽  
Lymphatic Transport ◽  
Lymph Duct

Stimulation of regional lymphatic and blood flow by epicutaneous oxazolone

2002 ◽  
Vol 93 (3) ◽  
pp. 966-973 ◽  
Author(s):  
Chufa He ◽  
Alan J. Young ◽  
Charles A. West ◽  
Mei Su ◽  
Moritz A. Konerding ◽  
...  
Keyword(s):  
Blood Flow ◽  
Visible Spectrum ◽  
Lymphatic Drainage ◽  
Lymph Flow ◽  
Vascular Network ◽  
Corrosion Casting ◽  
Subsequent Increase ◽  
Clinical Appearance ◽  
Early Increase ◽  
Lymph Duct

The application of the epicutaneous antigen oxazolone results in persistent induration and erythema; however, the relative changes in lymph and blood flow in the inflammatory skin are largely unknown. To define the contribution of lymph and blood flow to the clinical appearance of cutaneous inflammation, we studied the sheep ear after the application of oxazolone. As a model for the study of these changes, the sheep ear had several experimental advantages: 1) a simplified superficial vascular network, 2) defined lymphatic drainage, and 3) an avascular and alymphatic cartilaginous barrier. Lymph flow was continuously monitored by cannulation of the prescapular efferent lymph duct. Blood flow, as reflected by cutaneous erythema, was noninvasively measured by use of a visible-spectrum spectrophotometer. The application of the epicutaneous oxazolone resulted in increased ear thickness for >7 days. The lymph flow from the oxazolone-stimulated ear peaked between 24 and 48 h after oxazolone stimulation. Spectrophotometric evaluation indicated that the cutaneous erythema peaked 72–96 h after application of oxazolone. Corrosion casting and scanning electron microscopy of the microcirculation at 96 h after antigen stimulation demonstrated significant dilatation of the superficial vascular network. These results suggest a biphasic response to oxazolone stimulation: 1) an early increase in vascular permeability associated with increased lymph flow and 2) a subsequent increase in relative blood flow associated with a dilated inflammatory microcirculation.

Roentgenanatomie der Neugeborenenund Säuglingslunge

PEDIATRICS ◽  
1959 ◽  
Vol 23 (6) ◽  
pp. 1203-1203
Author(s):  
GERHART S. SCHWARZ
Keyword(s):  
Vascular System ◽  
Shoulder Girdle ◽  
Bronchial Tree ◽  
Fetal Life ◽  
Duct System ◽  
Lymph Duct

This book is much more than its modest title implies. It deals not only with the lung of newborns and infants but with all parts of the thorax. It treats in 17 separate chapters the shoulder girdle, the ribs and spine, the sternum, development of the lung during fetal life, anatomy of the bronchial tree, the vascular system, the lymph duct system, the thymus, diaphragm, the pleura and several other pathologic or anatomic problems. From this, one might deduce that it is merely a review of all that is known about the infant chest, bringing all of the better known papers on this subject under one roof. This is, however, not the case. This book is a report on the author's own investigation on the subjects enumerated above.

Uptake and metabolism of circulating fatty acids by rat intestine

1992 ◽  
Vol 263 (6) ◽  
pp. G927-G933 ◽  
Author(s):  
C. M. Mansbach ◽  
R. F. Dowell
Keyword(s):  
Fatty Acids ◽  
Steady State ◽  
Specific Activity ◽  
Femoral Vein ◽  
Tracer Injection ◽  
Previous Hypothesis ◽  
Injection Techniques ◽  
Lymph Duct ◽  
Glyceryl Trioleate ◽  
Uptake And Metabolism

The present study was designed to investigate the uptake and metabolism of circulating fatty acids by the intestinal mucosa in rats actively absorbing glyceryl trioleate given intraduodenally to determine the plasma fatty acid contribution to mucosal triacylglycerol. Rats with duodenal, femoral vein, carotid artery, and mesenteric lymph duct cannulas were used. [3H]oleate was constantly infused into the femoral vein while glyceryl trioleate was infused into the duodenum (135 mumol/h). After 5 h of infusion, a mass and radioactive steady state existed in the plasma and mucosa. At 6 h of infusion, the plasma oleate specific activity was sixfold greater than mucosal oleate and 50 times greater than mucosal triacylglycerol oleate; 86% of the mucosal oleate disintegrations/minute were in triacylglycerol. Chylomicron triacylglycerol oleate specific activity was less than that of the mucosa. Furthermore, the percentage of mucosal triacylglycerol acyl groups composed of oleate was greater than the percentage of oleate in mucosal free fatty acids. The data indicate that fatty acids are taken up by the mucosa during active fat absorption and metabolized primarily to triacylglycerols by the mucosa. The triacylglycerols in the mucosa synthesized from circulating fatty acids are selected against as a precursor of chylomicron triacylglycerol. The results support our previous hypothesis suggesting that the mucosa has at least two pools of neutral lipid (J. Lipid Res. 23: 1009-1019, 1982) and that steady-state conditions as performed here yield different results from previous work using bolus tracer injection techniques.

scholarly journals Defective Chylomicron Synthesis as a Cause of Delayed Particle Clearance in Diabetes?

2002 ◽  
Vol 3 (3) ◽  
pp. 171-178 ◽  
Author(s):  
Catherine Phillips ◽  
Claire Madigan ◽  
Daphne Owens ◽  
Patrick Collins ◽  
Gerald H. Tomkin
Keyword(s):  
Sodium Dodecyl ◽  
Apo B ◽  
Apo E ◽  
Gradient Gel Electrophoresis ◽  
Paired Control ◽  
Lymph Duct ◽  
Chylomicron Particle ◽  
Diabetic Rabbits ◽  
Chylomicron Metabolism ◽  
Chylomicron Triglyceride

Chylomicron metabolism is abnormal in diabetes and the chylomicron particle may play a very important role in atherosclerosis. The aim of this study was to examine the effect of diabetes on the metabolism of chylomicrons in cholesterol-fed alloxan diabetic and nondiabetic rabbits. Five diabetic rabbits and 5 control rabbits were given [C14]linoleic acid and [H3]cholesterol by gavage. Lymph was collected following cannulation of the lymph duct and radiolabelled chylomicrons were isolated by ultracentrifugation. The chylomicrons from each animal were injected into paired control and diabetic recipients. Lymph apolipoprotein (apo) B48, apo B100, and apo E were measured using sodium dodecyl sulfate–polyacrylamide gradient gel electrophoresis. Mean blood sugar of the diabetic donors and diabetic recipients were 19.7 ± 2.3 and 17.2 ± 3.2 mmol/L. Diabetic rabbits had significantly raised plasma triglyceride (10.8 ± 13.9 versus 0.8 ± 0.5 mmol/L,P< 0.02). There was a large increase in apo B48 in lymph chylomicrons in the diabetic donor animals (0.19 ± 0.10 versus 0.04 ± 0.02 mg/h,P< 0.01) and apo B100 (0.22 ± 0.15 versus 0.07 ± 0.07 mg/h,P< 0.05) and a reduction in apo E on the lymph chylomicron particle (0.27 ± 0.01 versus 0.62 ± 0.07 mg/mg apo B,P< 0.001). Diabetic recipients cleared both control and diabetic chylomicron triglyceride significantly more slowly than control recipients (P< 0.05). Clearance of control chylomicron cholesterol was delayed when injected into diabetic recipients compared to when these chylomicrons were injected into control recipients (P< 0.005). Clearance of diabetic chylomicron cholesterol was significantly slower when injected into control animals compared to control chylomicron injected into control animals (P< 0.02). In this animal model of atherosclerosis, we have demonstrated that diabetes leads to the production of an increased number of lipid and apo E–deficient chylomicron particles. Chylomicron particles from the control animals were cleared more slowly by the diabetic recipient (both triglyceride and cholesterol). The chylomicron particles obtained from the diabetic animals were cleared even more slowly when injected into the diabetic recipient. Although there was an initial delay in clearance of chylomicron triglyceride from the diabetic particle when injected into the control animals, the clearance over the first 15 minutes was not significantly different when compared to the control chylomicron injected into the control animal. On the other hand, the cholesterol clearance was significantly delayed. Thus, diabetes resulted in the production of an increased number of lipid- and apo E–deficient chylomicron particles. These alterations account, in part, for the delay in clearance of these particles.

scholarly journals Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation

2011 ◽  
Vol 53 (1) ◽  
pp. 95-104 ◽  
Author(s):  
Tam M. Nguyen ◽  
Janet K. Sawyer ◽  
Kathryn L. Kelley ◽  
Matthew A. Davis ◽  
Lawrence L. Rudel
Keyword(s):  
Cholesterol Absorption ◽  
Cholesterol Esterification ◽  
Intestinal Cholesterol Absorption ◽  
Lymph Duct

Lymphatic chylomicron size is inversely related to biliary phospholipid secretion in mice

2006 ◽  
Vol 290 (6) ◽  
pp. G1177-G1185 ◽  
Author(s):  
Anniek Werner ◽  
Rick Havinga ◽  
Frank Perton ◽  
Folkert Kuipers ◽  
Henkjan J. Verkade
Keyword(s):  
Lipid Absorption ◽  
Fat Absorption ◽  
Very Low Density Lipoproteins ◽  
Deficient Diet ◽  
Lipoprotein Subfractions ◽  
Core Surface ◽  
Lymph Duct ◽  
The Difference ◽  
Dietary Fat Absorption ◽  
Deficient Mice

Biliary phospholipids (PL) stimulate dietary fat absorption by facilitating intraluminal lipid solubilization and by providing surface components for chylomicron (CM) assembly. Impaired hepatic PL availability induces secretion of large very-low-density lipoproteins, but it is unclear whether CM size depends on biliary PL availability. Biliary PL secretion is absent in multidrug resistance protein 2-deficient ( Mdr2−/−) mice, whereas it is strongly increased in essential fatty acid (EFA)-deficient mice. We investigated lymphatic CM size and composition in mice with absent ( Mdr2−/−) or enhanced (EFA deficient) biliary PL secretion and in their respective controls under basal conditions and during enteral lipid administration. EFA deficiency was induced by feeding mice a high-fat, EFA-deficient diet for 8 wk. Lymph was collected by mesenteric lymph duct cannulation with or without intraduodenal lipid administration. Lymph was collected in 30-min fractions for up to 4 h, and lymphatic lipoprotein size was determined by dynamic light-scattering techniques. Lymph lipoprotein subfractions were isolated by ultracentrifugation, and lipid composition was measured. Lymphatic CMs were significantly larger in Mdr2−/− mice than in Mdr2+/+ controls either without (+50%) or with (+25%) enteral lipid administration, and molar core-surface ratios were increased [triglyceride (TG)-to-PL ratio: 4.4 ± 1.4 in Mdr2−/− mice vs. 2.7 ± 0.8 in Mdr2+/+ mice, P < 0.001]. In contrast, EFA-deficient mice secreted lipoproteins into lymph that were significantly smaller than in EFA-sufficient controls (173 ± 32 vs. 236 ± 47 nm), with correspondingly decreased core-surface ratios (TG-to-PL ratio: 3.0 ± 1.0 in EFA-deficient mice vs. 6.0 ± 1.9 in EFA-sufficient mice, P < 0.001). CM size increased during fat absorption in both EFA-deficient and EFA-sufficient mice, but the difference between the groups persisted. In conclusion, the present results strongly suggest that the availability of biliary PL is a major determinant of the size of intestinally produced lipoproteins both under basal conditions and during lipid absorption. Altered CM size may have physiological consequences for postprandial CM processing.

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