Pax4 Gene Transfer Induces α-to-ß Transdifferentiation and Improves the Therapeutic Efficacy of Islet Transplantation

Diabetes ◽

10.2337/db18-1742-p ◽

2018 ◽

Vol 67 (Supplement 1) ◽

pp. 1742-P

Author(s):

KESHAB R. PARAJULI ◽

YANQING ZHANG ◽

HONGJU WU

Keyword(s):

Gene Transfer ◽

Islet Transplantation ◽

Therapeutic Efficacy

Download Full-text

Capsid modifications overcome low heterogeneous expression of heparan sulfate proteoglycan that limits AAV2-mediated gene transfer and therapeutic efficacy in human ovarian carcinoma

Gynecologic Oncology ◽

10.1016/j.ygyno.2006.06.020 ◽

2006 ◽

Vol 103 (3) ◽

pp. 1054-1062 ◽

Author(s):

Wenfang Shi ◽

Akseli Hemminki ◽

Jeffrey S. Bartlett

Keyword(s):

Gene Transfer ◽

Heparan Sulfate ◽

Ovarian Carcinoma ◽

Therapeutic Efficacy ◽

Heparan Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Heterogeneous Expression ◽

Human Ovarian Carcinoma

Download Full-text

Automated Digital Image Analysis of Islet Cell Mass Using Nikon's Inverted Eclipse Ti Microscope and Software to Improve Engraftment may Help to Advance the Therapeutic Efficacy and Accessibility of Islet Transplantation across Centers

Cell Transplantation ◽

10.3727/096368913x667493 ◽

2015 ◽

Vol 24 (1) ◽

pp. 1-9 ◽

Author(s):

Valery Gmyr ◽

Caroline Bonner ◽

Bruno Lukowiak ◽

Valerie Pawlowski ◽

Nathalie Dellaleau ◽

...

Keyword(s):

Image Analysis ◽

Islet Transplantation ◽

Digital Image ◽

Therapeutic Efficacy ◽

Digital Image Analysis ◽

Download Full-text

Therapeutic Efficacy of Adenoviral-Mediated p53 Gene Transfer Is Synergistically Enhanced by Combined Use of Antisense Oligodeoxynucleotide Targeting Clusterin Gene in a Human Bladder Cancer Model

Neoplasia ◽

10.1593/neo.04478 ◽

2005 ◽

Vol 7 (2) ◽

pp. 171-179 ◽

Author(s):

Hideaki Miyake ◽

Kazuki Yamanaka ◽

Mototsugu Muramaki ◽

Isao Hara ◽

Martin E. Gleave

Keyword(s):

Bladder Cancer ◽

Gene Transfer ◽

Therapeutic Efficacy ◽

P53 Gene ◽

Antisense Oligodeoxynucleotide ◽

Human Bladder Cancer ◽

Cancer Model ◽

Human Bladder ◽

Combined Use ◽

Bladder Cancer Model

Download Full-text

Therapeutic efficacy of soluble receptor activator of nuclear factor-κB-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-08-0497 ◽

2008 ◽

Vol 7 (10) ◽

pp. 3389-3398 ◽

Author(s):

François Lamoureux ◽

Gaëlle Picarda ◽

Julie Rousseau ◽

Clothilde Gourden ◽

Séverine Battaglia ◽

...

Keyword(s):

Gene Transfer ◽

Mouse Model ◽

Therapeutic Efficacy ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Soluble Receptor ◽

Nonviral Gene Transfer ◽

Receptor Activator

Download Full-text

Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy

The Journal of Gene Medicine ◽

10.1002/jgm.1083 ◽

2007 ◽

Vol 9 (10) ◽

pp. 862-874 ◽

Author(s):

Stefania Lamartina ◽

Monica Cimino ◽

Giuseppe Roscilli ◽

Ernesta Dammassa ◽

Domenico Lazzaro ◽

...

Keyword(s):

Gene Expression ◽

Gene Therapy ◽

Gene Transfer ◽

Therapeutic Efficacy ◽

Stable Gene ◽

Proliferative Retinopathies ◽

Regulated Gene Expression

Download Full-text

444. Use of dsAAV8-Mediated Gene Transfer to Endogenous β-Cells To Investigate the Therapeutic Efficacy of Immunoregulatory Gene Products in Preventing the Onset of Diabetes in NOD Mice

Molecular Therapy ◽

10.1016/j.ymthe.2006.08.511 ◽

2006 ◽

Vol 13 ◽

pp. S171

Author(s):

Khaja K. Rehman ◽

Zhong Wang ◽

Xiao Xiao ◽

Paul D. Robbins

Keyword(s):

Gene Transfer ◽

Therapeutic Efficacy ◽

Nod Mice ◽

Gene Products ◽

Β Cells ◽

Onset Of Diabetes

Download Full-text

Adenovirus-mediated lymphotactin gene transfer improves therapeutic efficacy of cytosine deaminase suicide gene therapy in established murine colon carcinoma

Gene Therapy ◽

10.1038/sj.gt.3301082 ◽

2000 ◽

Vol 7 (4) ◽

pp. 329-338 ◽

Author(s):

D W Ju ◽

Q Tao ◽

D S Cheng ◽

W Zhang ◽

M Zhang ◽

...

Keyword(s):

Gene Therapy ◽

Gene Transfer ◽

Colon Carcinoma ◽

Therapeutic Efficacy ◽

Cytosine Deaminase ◽

Suicide Gene ◽

Suicide Gene Therapy ◽

Murine Colon Carcinoma ◽

Download Full-text

Gene transfer for hemophilia: can therapeutic efficacy in large animals be safely translated to patients?

Journal of Thrombosis and Haemostasis ◽

10.1111/j.1538-7836.2005.01460.x ◽

2005 ◽

Vol 3 (8) ◽

pp. 1682-1691 ◽

Author(s):

K. HIGH

Keyword(s):

Gene Transfer ◽

Therapeutic Efficacy ◽

Download Full-text

IL-37b gene transfer enhances the therapeutic efficacy of mesenchumal stromal cells in DSS-induced colitis mice

Acta Pharmacologica Sinica ◽

10.1038/aps.2015.51 ◽

2015 ◽

Vol 36 (11) ◽

pp. 1377-1387 ◽

Author(s):

Wei-qiang Wang ◽

Kui Dong ◽

Lu Zhou ◽

Guo-hui Jiao ◽

Cong-zhong Zhu ◽

...

Keyword(s):

Gene Transfer ◽

Stromal Cells ◽

Therapeutic Efficacy

Download Full-text

547. Untranslated Region Optimization Increases Transgene mRNA and Protein Levels, Resulting in Enhanced Therapeutic Efficacy of AAV Vector Gene Transfer In Vivo for Crigler-Najjar Syndrome

Molecular Therapy ◽

10.1016/s1525-0016(16)34156-9 ◽

2015 ◽

Vol 23 ◽

pp. S219-S220

Author(s):

Giuseppe Ronzitti ◽

Giulia Bortolussi ◽

Fanny Collaud ◽

Severine Charles ◽

Andres Muro ◽

...

Keyword(s):

Gene Transfer ◽

Therapeutic Efficacy ◽

Untranslated Region ◽

Protein Levels ◽

Vector Gene Transfer

Download Full-text