In Vitro Assessment of Chemical Activation Efficiency During In-office Dental Bleaching

2010 ◽  
Vol 35 (3) ◽  
pp. 287-294 ◽  
Author(s):  
A. C. Travassos ◽  
C. R. G. Torres ◽  
A. B. Borges ◽  
D. C. Barcellos
Keyword(s):  
Free Radicals ◽  
Clinical Relevance ◽  
Chemical Activation ◽  
Heat Sources ◽  
Dental Bleaching ◽  
Chemical Agents ◽  
Activation Efficiency ◽  
In Vitro Assessment ◽  
Damaging Effects

Clinical Relevance To accelerate the production of free radicals, chemical agents could act by reacting with H2O2, making bleaching faster, more efficient and safer, thus diminishing the possible damaging effects associated with the application of heat sources.

An In Vitro Assessment of the Effects of Three Surface Treatments on Repair Bond Strength of Aged Composites

2011 ◽  
Vol 36 (6) ◽  
pp. 608-617 ◽  
Author(s):  
TS Jafarzadeh Kashi ◽  
M Erfan ◽  
V Rakhshan ◽  
N Aghabaigi ◽  
FS Tabatabaei
Keyword(s):  
Bond Strength ◽  
Clinical Relevance ◽  
Surface Treatments ◽  
Bonding Agent ◽  
Acid Etching ◽  
Composite Surface ◽  
In Vitro Assessment

Clinical Relevance To achieve a durable composite-composite bond, it is highly recommended that besides selective grinding of the surface to be repaired, specific combinations of silane primer and bonding agent should be used, without the need for acid etching of the composite surface.

In vitro assessment of Labisia pumila and its constituents for interactions with CYPs, P-GP and PXR

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
VK Manda ◽  
OR Dale ◽  
C Awortwe ◽  
Z Ali ◽  
IA Khan ◽  
...  
Keyword(s):  
In Vitro Assessment ◽  
Labisia Pumila

In vitro Cytotoxicity and Genotoxicity Analysis of Ten Tannery Chemicals Using SOS/umu Tests and High-content In vitro Micronucleus Tests

2018 ◽  
Vol 21 (4) ◽  
pp. 262-270 ◽  
Author(s):  
Zehao Huang ◽  
Na Li ◽  
Kaifeng Rao ◽  
Cuiting Liu ◽  
Zijian Wang ◽  
...  
Keyword(s):  
Micronucleus Test ◽  
A549 Cells ◽  
Quantitative Structure Activity Relationship ◽  
In Vitro Cytotoxicity ◽  
Cytotoxic Effects ◽  
Qsar Analysis ◽  
Cell Assays ◽  
Micronucleus Tests ◽  
Damaging Effects

Background: More than 2,000 chemicals have been used in the tannery industry. Although some tannery chemicals have been reported to have harmful effects on both human health and the environment, only a few have been subjected to genotoxicity and cytotoxicity evaluations. Objective: This study focused on cytotoxicity and genotoxicity of ten tannery chemicals widely used in China. Materials and Methods: DNA-damaging effects were measured using the SOS/umu test with Salmonella typhimurium TA1535/pSK1002. Chromosome-damaging and cytotoxic effects were determined with the high-content in vitro Micronucleus test (MN test) using the human-derived cell lines MGC-803 and A549. Conclusion: The cytotoxicity of the ten tannery chemicals differed somewhat between the two cell assays, with A549 cells being more sensitive than MGC-803 cells. None of the chemicals induced DNA damage before metabolism, but one was found to have DNA-damaging effects on metabolism. Four of the chemicals, DY64, SB1, DB71 and RR120, were found to have chromosome-damaging effects. A Quantitative Structure-Activity Relationship (QSAR) analysis indicated that one structural feature favouring chemical genotoxicity, Hacceptor-path3-Hacceptor, may contribute to the chromosome-damaging effects of the four MN-test-positive chemicals.

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