Motion Videocapture and Treadmill to Study Postural Reactivity and Transition: Application to the condition of “Dry” Immersion in Parkinson's Disease

2021 ◽  
Author(s):  
Alexander Meigal ◽  
Olesya Tretjakova ◽  
Liudmila Gerasimova-Meigal ◽  
Kirill Prokhorov ◽  
Irina Sayenko
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dry Immersion

Dry Immersion as a Novel Physical Therapeutic Intervention for Rehabilitation of Parkinson’s Disease Patients: A Feasibility Study

2018 ◽  
Vol 28 (05) ◽  
pp. 275-281 ◽  
Author(s):  
A. Meigal ◽  
L. Gerasimova-Meigal ◽  
I. Saenko ◽  
N. Subbotina
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Rating Scale ◽  
Rehabilitation Program ◽  
Motor Symptoms ◽  
Dry Immersion ◽  
Rehabilitation Potential ◽  
Disease Rating ◽  
Pre Treatment ◽  
Non Motor Symptoms

Abstract Background The study was aimed at evaluating therapeutic effect of analogue microgravity in a form of “dry immersion” (DI) on motor and non-motor symptoms in patients with Parkinson’s disease (PD). Methods A group of 12 PD patients aged 67 (63–68) years, Hoenh and Yahr staged 1–3, participated in this study. During DI a subject wrapped in a thin waterproof material was immersed in a bathtub at 31°C. The rehabilitation program included 7 DI sessions (45 min each, 2 times per week, on-medication). The Unified Parkinson’s Disease Rating Scale parts I, II and III (UPDRS-I/II/III) and the Hamilton’s Depression Rate Scale (HDRS) were applied before the 1st, after 4th and 7th DI session, and 2 weeks and 2 months after the whole DI program. Results The UPDRS-III score, HDRS, and rigidity signs score have significantly decreased by 16–35% two weeks after the DI program. Two months after completion of the DI program all studied parameters regained their pre-treatment values. The UPDRS-I, II, tremor and akinesia signs score did not respond to the DI program. Conclusion The DI program promises rehabilitation potential for patients with parkinsonism.

scholarly journals Motor-cognitive Functions in Parkinson’s Disease Patients across the Program of "Dry" Immersion: a Pilot Study

2018 ◽  
Vol 9 ◽  
Author(s):  
Alexander Meigal ◽  
Liudmila Gerasimova-Meigal ◽  
Olesya Tretiakova ◽  
Kirill Prokhorov ◽  
Nataliya Subbotina ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pilot Study ◽  
Cognitive Functions ◽  
Dry Immersion

scholarly journals Autonomic Function in Parkinson's Disease Subjects Across Repeated Short-Term Dry Immersion: Evidence From Linear and Non-linear HRV Parameters

2021 ◽  
Vol 12 ◽  
Author(s):  
Liudmila Gerasimova-Meigal ◽  
Alexander Meigal ◽  
Nadezhda Sireneva ◽  
Irina Saenko
Keyword(s):  
Parkinson’S Disease ◽  
Heart Rate ◽  
Parkinson's Disease ◽  
Frequency Domain ◽  
Autonomic Function ◽  
Linear Time ◽  
Hypotensive Effect ◽  
Compensatory Mechanisms ◽  
Dry Immersion ◽  
Non Linear

Several studies have shown that “dry” immersion appears as a promising method of rehabilitation for Parkinson's disease. Still, little is known about the cardiovascular reaction in “dry” immersion (DI), especially in Parkinson's disease (PD). Therefore, this study was aimed to evaluate the effect of repeated 45-min DI sessions on autonomic function in subjects with PD. The study group consisted of 20 subjects with PD [13 men, seven women, aged 51–66 years old, Hoehn & Yahr (H&Y) staged 1–3] were enrolled in the study according to inclusion and non-inclusion criteria. The DI program was comprised of seven 45-min DI sessions, applied within 25–30 days. Blood pressure (BP), heart rate (HR), and electrocardiogram (ECG) in the standard lead II were recorded at 1st, 4th, and 7th DI, before, on the 15, 30, and 40th min of DI session. Autonomic function was assessed with analysis of heart rate variability (HRV) using Kubios Standard version 2 software. Linear (time- and frequency-domain) and non-linear (correlation dimension, entropies, DFA1 and DFA2, percent of determinism, and recurrence) were computed. At baseline condition, time- and frequency-domain HRV parameters showed low variability of HR, which indicates reduced autonomic neurogenic control of HR. Throughout the DI session, systolic and diastolic BP has decreased by 5–7 mm Hg (p < 0.001), and time- and frequency-domain parameters of HRV have significantly increased, what can be regarded as compensatory mechanisms of hemodynamics during DI. The structure of the regulatory input to the heart seen by HRV was characterized by low complexity and reduced autonomic neurogenic control of HR. Across the program of DI sessions, the hypotensive effect was documented, but no notable modification of the HRV-parameters was found. The absence of long-term modification of the studied parameters can be attributed both to deconditioning environmental effect of DI and limited adaptation of the organism due to neurodegeneration in PD. That should be taken into consideration when planning rehabilitation measures in subjects of older age and chronic somatic diseases with modeled microgravity.

scholarly journals Program of Seven 45-min Dry Immersion Sessions Improves Choice Reaction Time in Parkinson’s Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Alexander Yu. Meigal ◽  
Olesya G. Tretjakova ◽  
Liudmila I. Gerasimova-Meigal ◽  
Irina V. Sayenko
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Reaction Time ◽  
Neural Plasticity ◽  
Processing Time ◽  
Central Processing ◽  
Dry Immersion ◽  
Simple Rt ◽  
Central Processing Time ◽  
Study Hypothesis

The study hypothesis held that in subjects with Parkinson’s disease (PD), the reaction time (RT) tests of the higher cognition demand would have more readily improved under the program of analog microgravity (μG) modeled with “dry” immersion (DI). To test this hypothesis, 10 subjects with PD have passed through a program of seven DI sessions (each 45 min long) within 25–30 days, with overall μG dose 5 1/4 h. Five patients were enrolled as controls, without DI (noDI group). Simple RT (SRT), disjunctive RT (DRT), and choice RT (CRT) were assessed in four study points: before the DI program (preDI), 1 day after the DI program (postDI), 2 weeks after the DI program (DI2w), and 2 months after the DI program (DI2m). The motor time (MT) was assessed with the tapping test (TT). Additionally, signal detection time (SDT) and central processing time (CPT) were extracted from the data. Before the program of DI, the RT tests are in accordance with their cognition load: SRT (284 ± 37 ms), DRT (338 ± 38 ms), and CRT (540 ± 156 ms). In accordance with the hypothesis, CRT and DRT have improved under DI by, respectively, 20 and 8% at the study point “DI2w,” whereas SRT, SDT, and MT did not change (<5% in the preDI point, p > 0.05). Thus, the program of DI provoked RT improvement specifically in the cognitively loaded tasks, in a “dose of cognition-reaction” manner. The accuracy of reaction has changed in none of the RT tests. The neurophysiologic, hormonal/neuroendocrine, behavioral, neural plasticity, and acclimation mechanisms may have contributed to such a result.

Evaluation of Efferent Auditory System and Hearing Quality in Parkinson's Disease: Is the Difficulty in Speech Understanding in Complex Listening Conditions Related to Neural Degeneration or Aging?

2020 ◽  
pp. 1-9
Author(s):  
Nuriye Yıldırım Gökay ◽  
Bülent Gündüz ◽  
Fatih Söke ◽  
Recep Karamert
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Auditory System ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Auditory Pathway ◽  
Normal Hearing ◽  
System Function ◽  
Distortion Product

Purpose The effects of neurological diseases on the auditory system have been a notable issue for investigators because the auditory pathway is closely associated with neural systems. The purposes of this study are to evaluate the efferent auditory system function and hearing quality in Parkinson's disease (PD) and to compare the findings with age-matched individuals without PD to present a perspective on aging. Method The study included 35 individuals with PD (mean age of 48.50 ± 8.00 years) and 35 normal-hearing peers (mean age of 49 ± 10 years). The following tests were administered for all participants: the first section of the Speech, Spatial and Qualities of Hearing Scale; pure-tone audiometry, speech audiometry, tympanometry, and acoustic reflexes; and distortion product otoacoustic emissions (DPOAEs) and contralateral suppression of DPOAEs. SPSS Version 25 was used for statistical analyses, and values of p < .05 were considered statistically significant. Results There were no statistically significant differences in the pure-tone audiometry thresholds and DPOAE responses between the individuals with PD and their normal-hearing peers ( p = .732). However, statistically significant differences were found between the groups in suppression levels of DPOAEs and hearing quality ( p < .05). In addition, a statistically significant and positive correlation was found between the amount of suppression at some frequencies and the Speech, Spatial and Qualities of Hearing Scale scores. Conclusions This study indicates that medial olivocochlear efferent system function and the hearing quality of individuals with PD were affected adversely due to the results of PD pathophysiology on the hearing system. For optimal intervention and follow-up, tasks related to hearing quality in daily life can also be added to therapies for PD.

Accessible Internet Training for People With Aphasia and Parkinson's Disease

2004 ◽  
Vol 9 (2) ◽  
pp. 10-13
Author(s):  
Linda Worrall ◽  
Jennifer Egan ◽  
Dorothea Oxenham ◽  
Felicity Stewart
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease
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