scholarly journals Differentiated combined therapy of polycystic ovary syndrome for patients with obesity

2014 ◽  
Vol 18 (1 (69)) ◽  
Author(s):  
Y. V. Onyshchenko ◽  
N. N. Rozhkovska
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Hormone Level ◽  
Polycystic Ovary ◽  
Combined Therapy ◽  
Infertility Treatment ◽  
Luteinizing Hormone Level ◽  
Complex Treatment ◽  
Ovary Syndrome ◽  
Explicit Correlation ◽  
Positive Effect

Obesity is one of pathognomonic symptoms of polycystic ovary syndrome (PCOS). According to different data sources its frequency among patients with PCOS ranges from 45 to 50 %. Efficiency of differentiated complex treatment of patients with PCOS is studied with taking body mass index (BMI) into account. Obtained data show positive effect of combined infertility treatment that included Metformin for insulin resistance correction as menstrual function and ovulation normalization in 58,7 % of patients with PCOS. Treatment with Metformin results in normalization of luteinizing hormone level which has explicit correlation with risk of 1st trimester miscarriages.

A Clomiphene Citrate and Letrozol Varsus Tamoxifen and Letrozole as an Infertility Treatment in Women with Polycystic Ovary Syndrome

2015 ◽  
Vol 18 (6) ◽  
pp. 300-303 ◽  
Author(s):  
Rasekhjahromi Athar ◽  
Maalhagh Mehrnoosh ◽  
Hosseinpoor Masoumeh ◽  
Farhang Hooshmand ◽  
Alavi Fatemeh
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Clomiphene Citrate ◽  
Infertility Treatment ◽  
Ovary Syndrome

A cost comparison of infertility treatment for clomiphene resistant polycystic ovary syndrome

1999 ◽  
Vol 78 (3) ◽  
pp. 212-216
Author(s):  
Margareta Fridström ◽  
Peter Sjöblom ◽  
Maria Granberg ◽  
Torbjörn Hillensjö
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Infertility Treatment ◽  
Cost Comparison ◽  
Ovary Syndrome

scholarly journals Efficiency of application of metformin and its combination with combined oral ontrceptive, containing drospirenone, in women with polycystic ovary syndrome

2013 ◽  
Vol 62 (4) ◽  
pp. 55-60
Author(s):  
Yelena Leonidovna Soboleva
Keyword(s):  
Menstrual Cycle ◽  
Polycystic Ovary Syndrome ◽  
Carbohydrate Metabolism ◽  
High Efficiency ◽  
Polycystic Ovary ◽  
Therapeutic Option ◽  
Combined Therapy ◽  
Combined Treatment ◽  
Ovary Syndrome ◽  
Restoration Of Fertility

The article represents results of monotherapy with metformin, as well as combined treatment with metformin and combined oral contraceptive (COC), containing drospirenone, in patients with polycystic ovary syndrome (PCOS). In general, treatment was given to 42 patients with PCOS. Combined treatment was prescribed to 18 of them. Equally high efficiency of both schemes of treatment in correction of disorders of carbohydrate metabolism was demonstrated. But efficacy of metformin alone in restoration of ovulatory menstrual cycle was low – ovulation occurred in 3 patients (13 %) and only two women (8.7 %)became pregnant. These results do not allow recommendation of monotherapy with this medication for restoration of fertility. Implication of combined therapy has shown benefits in normalization of menstrual cycle, ultrasound structure and volume of ovaries. COC with drospirenone also has antiandrogenic properties. So combination of metformin with COC, containing drospirenone, can be recommended as a first-line therapeutic option for patients with PCOS and impaired carbohydrate metabolism.

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