Quantitative Analysis of Different Lymphocyte Subtypes in Children’s Adenoid Tissues Who Have Allergic Rhinitis and Adenoid Hypertrophy

Tonsil hypertrophy (TH) is very common in children. Previously, it has been reported that an inverse relationship exists between adenoid hypertrophy (AH) and allergic rhinitis (AR). This study aimed to investigate the possible relationship between tonsil volume and AR diagnosis in a group of children complaining of upper airways obstruction. Globally, 171 children (91 boys; mean age, 6.6 years) were studied. Clinical visit, nasal endoscopy, and skin-prick test were performed in all patients. TH and anterior nasal obstruction were graded using the Friedman's classifications. Adenoid volume was graded using the Parikh's classification. Fifty-eight children (33.9%) had relevant TH (grades 3–4); 77 children (44.94%) had AR. There was a strong correlation (gamma = 0.564; p < 0.001) between TH and AH. Tonsil volume was inversely associated with AR diagnosis (odds ratio [OR], 0.314). Risk factors for TH were intense mucosal inflammation (pale mucous membranes) and AH (OR, 3.54 and 2.856, respectively). This study shows that large tonsils are negatively associated with allergy, whereas intense inflammation is a risk factor for TH; AH may be frequently associated with TH.

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Aeroallergen IgE profile, adenoid hypertrophy, and childhood allergic rhinitis in urban China

10.22541/au.160315206.68383893/v1 ◽

2020 ◽

Author(s):

Yihang Lin ◽

Xiaoqing Rui ◽

Junyang Li ◽

Jie Chen ◽

YOUJIN LI

Keyword(s):

Allergic Rhinitis ◽

Urban China ◽

Adenoid Hypertrophy

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Effect of Local versus Systemic Steroids in Treatment of Children with Otitis Media with Effusion

QJM ◽

10.1093/qjmed/hcaa047.007 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

A G Shafik ◽

M S Hassabalah ◽

A M Maarouf ◽

M K Elghobashy

Keyword(s):

Allergic Rhinitis ◽

Otitis Media ◽

Clinical Symptoms ◽

Otitis Media With Effusion ◽

University Hospital ◽

Adjunctive Treatment ◽

Oral Steroid ◽

Adenoid Hypertrophy ◽

Systemic Steroids ◽

Significant Difference

Abstract Background otitis media with effusion (OME) or glue ear is the collection of fluid behind the tympanic membrane without inflammatory signs present for 6 weeks. Aim of the Work comparing the effect of intra nasal versus systemic steroids in treatment of children with Otitis media with effusion as regard: Improvement of clinical symptoms and Audiological findings. Subjects and Methods this study is a prospective, case control study on the effects of intranasal versus systemic steroids on children with otitis media with effusion. This thesis study was conducted on 30 patients diagnosed according to clinical and audiological assessment recruited from otorhinolaryngology outpatient clinic Ain Shams university hospital from October 2017 to July 2018. An informed consent was obtained from each patient or control or their legal guardians before enrolment in the study. Results however, statistically there is no significant relation between the occurrence of complete resolution of OME and the route of administration of steroid (either intranasal or systemic), whatever the cause either allergic rhinitis or adenoid hypertrophy. So we can use either intranasal or systemic steroids in management of otitis media with effusion in children with either allergic rhinitis or adenoid hypertrophy or both. Conclusion both topical intranasal and oral steroids are effective adjunctive treatment for OME in children in the short term, without significant difference between the two methods, and thus oral steroid complications could be avoided using local steroid spray.

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