CLINICAL CASES OF DETECTION OF CHROMOSOMALLY INTEGRATED HUMAN HERPESVIRUS TYPE 6 IN TWO CHILDREN

2021 ◽  
Vol 100 (2) ◽  
pp. 271-276
Author(s):  
N.V. Zinovieva ◽  
◽  
M.A. Gordukova ◽  
O.V. Barabanova ◽  
◽  
...  
Keyword(s):  
Antiviral Therapy ◽  
Chronic Infection ◽  
Human Herpesvirus ◽  
Chromosomal Integration ◽  
Human Herpes ◽  
Herpesvirus Type ◽  
Clinical Observations ◽  
Human Herpes Virus ◽  
Human Herpesvirus Type ◽  
Human Herpes Virus Type

The article describes two clinical observations of the detection of chromosomally integrated human herpes virus type 6 (HHV-6). In both cases, the children were referred to an immunologist with a diagnosis of chronic infection caused by the human herpesvirus type 6, in order to exclude an immunodeficiency state and determine the strategies of treating this infection. However, during the molecular biological examination of children, a chromosomal integration of HHV-6 was determined, which led to a revision of the diagnostic search and abandoning massive antiviral therapy.

Early human herpes virus type 6 reactivation in umbilical cord blood allogeneic stem cell transplantation

2016 ◽  
Vol 57 (11) ◽  
pp. 2555-2559 ◽  
Author(s):  
Frank Cirrone ◽  
Cindy Ippoliti ◽  
Hanhan Wang ◽  
Xi Kathy Zhou ◽  
Usama Gergis ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Allogeneic Stem Cell Transplantation ◽  
Umbilical Cord Blood ◽  
Human Herpes ◽  
Human Herpes Virus ◽  
Early Human ◽  
Human Herpes Virus Type

scholarly journals Human Herpes Virus Type 6 Can Cause Skin Lesions at the BCG Inoculation Site Similar to Kawasaki Disease

2012 ◽  
Vol 228 (4) ◽  
pp. 351-353 ◽  
Author(s):  
Yosuke Kakisaka ◽  
Tomoichiro Ohara ◽  
Saori Katayama ◽  
Tasuku Suzuki ◽  
Shu Sasai ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Virus Type ◽  
Herpes Virus ◽  
Skin Lesions ◽  
Human Herpes ◽  
Inoculation Site ◽  
Human Herpes Virus ◽  
Herpès Virus ◽  
Human Herpes Virus Type

Increased prevalence of human herpesvirus type 8 (HHV-8) genome among blood donors from North-Western Argentina

2016 ◽  
Vol 89 (3) ◽  
pp. 518-527 ◽  
Author(s):  
María Laura Hulaniuk ◽  
Oscar Torres ◽  
Sonia Bartoli ◽  
Lisandro Fortuny ◽  
Leandro Burgos Pratx ◽  
...  
Keyword(s):  
Blood Donors ◽  
Human Herpesvirus ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
North Western

scholarly journals Primary infection with human herpes virus type 6, post-pediatric liver transplantation-A pathogen to remember

2018 ◽  
Vol 21 (1) ◽  
pp. e13014
Author(s):  
Adi Pappo-Toledano ◽  
Sara Dovrat ◽  
Zvia Soufiev ◽  
Yael Mozer-Glassberg ◽  
Irit Krause ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Virus Type ◽  
Primary Infection ◽  
Herpes Virus ◽  
Pediatric Liver Transplantation ◽  
Human Herpes ◽  
Human Herpes Virus ◽  
Pediatric Liver ◽  
Herpès Virus ◽  
Human Herpes Virus Type

scholarly journals Immunohistochemical detection of the latent nuclear antigen-1 of the human herpesvirus type 8 to differentiate cutaneous epidemic Kaposi sarcoma and its histological simulators

2013 ◽  
Vol 88 (2) ◽  
pp. 243-246 ◽  
Author(s):  
Patricia Fonseca Pereira ◽  
Tullia Cuzzi ◽  
Maria Clara Gutierrez Galhardo
Keyword(s):  
Kaposi's Sarcoma ◽  
Human Herpesvirus ◽  
Kaposi Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Nuclear Antigen ◽  
Immunohistochemical Detection ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
Skin Biopsies ◽  
Latent Nuclear Antigen

Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis. The aim of this study is to confirm that immunohistochemistry is a valuable tool for differentiating KS from its simulators in skin biopsies of HIV patients. Immunohistochemical and histological analyses were performed in 49 Kaposi's sarcoma skin biopsies and 60 of its histological simulators. Positivity was present in the 49 Kaposi's sarcoma skin biopsies and no staining was observed in the 60 simulators analyzed, resulting in sensibility and specificity of 100%. HHV-8 immunohistochemical detection is an effective tool for diagnosing Kaposi's sarcoma, especially in early lesions in which neoplastic features are not evident. It also contributes to its histological differential diagnosis.

scholarly journals Clinical Aspects of Bacterial Corneal Ulcer Prolonged Course, the Role of Herpes Viruses in Its Pathogenesis, Treatment

2019 ◽  
Vol 16 (1S) ◽  
pp. 40-44
Author(s):  
V. V. Neroev ◽  
L. A. Katargina ◽  
L. A. Kovaleva ◽  
G. I. Krichevskaya ◽  
N. V. Balatskaya
Keyword(s):  
Corneal Ulcer ◽  
Human Herpesvirus ◽  
Clinical Aspects ◽  
Herpesvirus Type ◽  
Corneal Ulcers ◽  
Barr Virus ◽  
Human Herpesvirus Type ◽  
Epstein Barr ◽  
Simplex Virus

Purpose: to study the role of human herpesviruses (HHV) in the pathogenesis of prolonged bacterial corneal ulcers. Patients and methods. 117 patients with bacterial corneal ulcer were examined. Two groups were identified: a favorable course-with duration of bacterial corneal ulcer epithelialization for 17 days (62 people) and a prolonged course with a persistent ulcer more than 17 days (55 people). Blood samples (n = 117) and scrapes from corneal ulcer (n = 117) were investigated in polymerase chain reaction (PCR) for the presence of deoxyribonucleic acid (DNA) of Herpes simplex virus (HSV1, 2), Epstein-Barr virus (EBV), Human herpesvirus type 6, 7 (HHV-6, HSV-7). Results. The HSV1, 2 and EBV genomes were detected in the cornea significantly more often in BCU of prolonged course compared with a favorable course (HSV1, 2 p = 0.012; EBV p = 0.012), and HHV-6 was detected not only in the cornea (p = 0.000), but also and in blood (p = 0.007). In patients with HHV DNA in corneal scarps and/or blood, after resorption of purulent infiltrate, corneal epithelialization was absent, and the use of antiherpetic drugs allowed to reduce the completion time of BCU epithelialization. Conclusion. The role of HHV-6, EBV, HSV 1, 2 in the pathogenesis of bacterial corneal ulcer of protracted course was revealed. The expediency of examination of patients with bacterial corneal ulcer on HHV is shown, a method of treatment is proposed, including antiherpetic therapy, which makes it possible to prevent the development of a protracted course.

scholarly journals Antiviral activity of Stachys Thracica Dav. extracts against Human Herpes virus type 1 and 2

Biodiscovery ◽  
2017 ◽  
Vol 20 ◽  
pp. e15022
Author(s):  
Petya Angelova ◽  
Venelin Tsvetkov ◽  
Anton Hinkov ◽  
Daniel Todorov ◽  
Kalina Shishkova ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Virus Type ◽  
Herpes Virus ◽  
Human Herpes ◽  
Human Herpes Virus ◽  
Herpès Virus ◽  
Human Herpes Virus Type
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