Preliminary data regarding the influence of the COL1a1 rs2249492 polymorphism on the risk of malocclusion in the Romanian population

2021 ◽  
Vol 66 (2) ◽  
pp. 45-51
Author(s):  
Adina Maria Topârcean ◽  
◽  
Arina Acatrinei ◽  
Ioana Rusu ◽  
Cristina Mircea ◽  
...  
Keyword(s):  
Preliminary Data ◽  
Expression Patterns ◽  
Phenotypic Expression ◽  
Class Ii ◽  
Class Ii Malocclusion ◽  
Skeletal Class ◽  
Skeletal Class Ii ◽  
Increased Risk ◽  
Romanian Population ◽  
Mandibular Retrognathism

Malocclusion is a condition characterized by diverse phenotypic expression patterns, with a complex underlying genetic background. COL1a1 is one of the genes that has been previously associated with malocclusion, with one particular SNP, rs2249492 (C>G, C>T), having been linked with an increased risk of skeletal class II malocclusion. In this paper, making use of DNA sequencing and cephalometric measurements, we present preliminary data regarding the association between the rs2249492 SNP and the risk of malocclusion in the Romanian population, illustrated as continuous, rather than categorical phenotypes. The results show a tendency towards a Class II pattern determined by mandibular retrognathism, rather than maxillary prognathism among the individuals possessing the mutant allele. Subsequent studies on larger sample sizes should include statistical analysis focused on associations between the rs2249492 allele and continuous phenotypic variation inside, but not restricted to Class II malocclusion, in order to acquire a more detailed picture of the interaction between the polymorphism and this complex condition

scholarly journals Ortho-surgical Management of Severe Skeletal Class II Div 2 Malocclusion in Adult

2017 ◽  
Vol 7 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Suchita Tarvade Daokar ◽  
Gauri Agrawal ◽  
Charushila Chaudhari ◽  
Sheetal Yamyar
Keyword(s):  
Case Report ◽  
Surgical Approach ◽  
Class Ii ◽  
Mandibular Advancement ◽  
Class Ii Malocclusion ◽  
Growth Modulation ◽  
Skeletal Class ◽  
Skeletal Class Ii ◽  
Bilateral Sagittal Split Osteotomy ◽  
Mandibular Retrognathism

Skeletal Class II malocclusion is attributed to maxillary prognathism, mandibular retrognathism or combination of both. In adolescent cases, the treatment includes growth modulation with headgear or myofunctional appliances. However in adults, optimum esthetic and functional efficacy can be achieved by orthodontic-surgical combination. This case report describes a 21 years old post-pubertal male with severe skeletal Class II discrepancy with normal maxilla and retrognathic mandible. The case was treated with bilateral sagittal split osteotomy (BSSO) with mandibular advancement approach. Straight profile, pleasing esthetics, bilateral Class I molar and canine relationship, normal overjet and overbite were achieved because of a combined ortho-surgical approach.

Uso de propulsor mandibular fixo Flex Developer como recurso no tratamento da Classe II em paciente não colaborador

2020 ◽  
Vol 13 (52) ◽  
pp. 40-51
Author(s):  
Renato Barcellos Rédua
Keyword(s):  
Upper Airway ◽  
Class Ii ◽  
Class Ii Malocclusion ◽  
Skeletal Class ◽  
Advantages And Disadvantages ◽  
Skeletal Class Ii ◽  
High Incidence ◽  
Therapeutic Alternatives ◽  
Smile Aesthetics ◽  
Treatment Alternatives

Class II malocclusion has a high incidence in the population, which may compromise smile aesthetics, occlusion function and stability. Skeletal Class II may affect facial aesthetics and upper airway volume. Class II malocclusion is routinely associated with skeletal Class II condition, having as treatment alternatives the use of Extra Buccal Appliance (EBA) or removable or fixed propulsor appliance. This article describes a case of a patient who did not accept the use of EBA and so it was fitted a Flex Developer propulsor for Class II correction and discussed the advantages and disadvantages of therapeutic alternatives for Class II correction.

A Comparison of Five Different Methods for Describing Sagittal Jaw Relationship

1993 ◽  
Vol 20 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Johannes Kirchner ◽  
Stephen Williams
Keyword(s):  
Correlation Analysis ◽  
Treatment Planning ◽  
Class Ii ◽  
Diagnosis And Treatment ◽  
Class Ii Malocclusion ◽  
Skeletal Class ◽  
Skeletal Class Ii ◽  
Accurate Picture

Analysis of sagittal jaw relationship is important in orthodontic diagnosis and treatment planning, and can be investigated by angular or linear parameters. In the present study an analysis was performed using profile cephalograms of 40 children with skeletal Class II malocclusion. A correlation analysis is presented, involving five different methods of expressing sagittal jaw relationships. Whilst some degree of agreement could be noted, it was not possible to suggest a pair of measurements, which in combination, could give a more accurate picture of sagittal jaw relationships.

Abordagem precoce da má oclusão de Classe II esquelética com atresia maxilar e mordida aberta anterior e o uso de alinhadores ClearCorrect – relato de caso

2021 ◽  
Vol 14 (53) ◽  
pp. 97-106
Author(s):  
Roberto Hideo Shimizu ◽  
Isabela Almeida Shimizu ◽  
Ana Cláudia M. Melo Toyoffuku ◽  
Rebecca Marquesini ◽  
Tatiane Travizan Lima ◽  
...  
Keyword(s):  
Treatment Time ◽  
Low Complexity ◽  
Class Ii ◽  
Open Bite ◽  
Class Ii Malocclusion ◽  
Anterior Open Bite ◽  
Skeletal Class ◽  
Posterior Crossbite ◽  
Skeletal Class Ii ◽  
High Predictability

Adequate planning and early treatment of Angle Class II malocclusion with maxillary atresia and anterior open bite provides harmonization of maxillomandibular bone bases in the three planes of space. Orthodontic aligners have emerged as an alternative treatment having the following advantages: being more aesthetic and more comfortable for the patient, less treatment time when they are correctly indicated, less chairside time, less complications, possibility of remote monitoring, easier feeding, and dental hygiene. On the other hand, they offer difficulties to treat adults with severe skeletal Class II malocclusions, posterior crossbite and anterior open bite. Therefore, the objective of this clinical case report is to early correct skeletal Class II malocclusion with maxillary atresia through the use of mechanical orthopedics and devices that help eliminate habits and close the anterior open bite, and later the use of orthodontic aligners to finish the treatment. It was concluded that the early interceptive treatment of malocclusion was efficient to harmonize the bone bases in the anteroposterior, vertical, and transversal directions, changing this malocclusion from high to low complexity and, consequently, highly predictable and with an excellent prognosis for treatment with orthodontic aligners. The treatment with ClearCorrect aligners corrected the occlusion in a shorter period of time when compared to corrective orthodontics and with a high predictability in relation to the virtual setup.

scholarly journals Comparative Study on the Efficiency of Intermaxillary Elastic Polymers used in the Treatment of Skeletal Class II Malocclusions in Growing Patients

2019 ◽  
Vol 56 (2) ◽  
pp. 341-345 ◽  
Author(s):  
Luminita Ligia Vaida ◽  
Raluca Dima ◽  
Emilia Albinita Cuc ◽  
Bianca Maria Negrutiu ◽  
Abel Emanuel Moca ◽  
...  
Keyword(s):  
Class Ii ◽  
Class Ii Malocclusion ◽  
Therapeutic Approaches ◽  
Mandibular Growth ◽  
Skeletal Class ◽  
Skeletal Class Ii ◽  
Orthodontic Patients ◽  
Group 2 ◽  
Class Ii Elastics ◽  
Group 1

The aim of this study was to evaluate the efficiency in using intermaxillary elastics to stimulate mandibular growth and advancement in orthodontic patients diagnosed with skeletal Class II malocclusion as well as to compare the use of these Class II elastics in two different therapeutic approaches. The sample consisted of 60 orthodontic patients aged 10-15 years, 34 girls and 26 boys. The sample was divided into two equal groups (each consisting of 30 patients). Patients belonging to the first group (Group 1) were subjected to 1/4�� - 6.0 oz elastics and were advised to change the elastic every 24 hours. Patients belonging to the second group (Group 2) were subjected to 1/4�- 4.5 oz elastics but with a recommendation to change the elastics every 12 hours. In order to evaluate the effectiveness of these two types of Class II elastics on mandibular growth and advancement, the value of the SNB angle at the beginning of the treatment (T1) was compared with the value of the SNB angle after 5 months of wearing intermaxillary elastics (T2). All patients showed statistically significant increased values of the SNB angle during the orthodontic treatment (p[0.001). Patients in Group 2 showed a significantly higher statistical increase (p[0.05) than patients in Group 1.

scholarly journals A combined Surgical-Orthodontic treatment in skeletal Class II malocclusion patients

2021 ◽  
Vol 3 (2) ◽  
pp. 82-87
Author(s):  
Prathyaksha Shetty ◽  
Dipjyothi Baruah ◽  
Amit Rekhawat ◽  
Karthik Cariappa ◽  
Sujala Ganapati Durgekar ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
Class Ii ◽  
Mandibular Advancement ◽  
Class Ii Malocclusion ◽  
Skeletal Class ◽  
Sagittal Split Osteotomy ◽  
Skeletal Class Ii ◽  
Facial Esthetics ◽  
Bilateral Sagittal Split Osteotomy ◽  
Common Problems

Skeletal Class II malocclusion with mandibular deficiency is one of the most common problems that patients seek treatment. Adult patients with severe skeletal Class II malocclusion need orthognathic surgery for successful treatment. Bilateral sagittal split osteotomy (BSSO) is the most often preferred technique for these patients. This case report briefs about two male patient of age 24 years presented with Class II Skeletal relation, mesoprosopic facial form, horizontal growth pattern and Angle’s Class II div 1 malocclusion who were treated with Bilateral sagittal split osteotomy (BSSO) mandibular advancement. The ideal anteroposterior relation was established along with a Class I molar, incisor, canine relationship and ideal overjet, overbite and the overall facial esthetics were significantly improved. Combined surgical-orthodontic treatment aims to obtain a more harmonious facial, skeletal, dental and soft tissue relationship with an added patient self esteem.

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