scholarly journals Antidepressant Activity of SGLT – 2 Inhibitors in Albinomice, an Experimental Study

2018 ◽  
Vol 8 (2) ◽  
pp. 1-6
Author(s):  
Saritha. M. K et al., Saritha. M. K et al., ◽  
Keyword(s):  
Experimental Study ◽  
Antidepressant Activity

scholarly journals AN EXPERIMENTAL STUDY EVALUATING THE INFLUENCE OF QUERCETIN ON MONOSODIUM GLUTAMATE-INDUCED DEPRESSION IN SWISS ALBINO MALE MICE

2019 ◽  
pp. 292-294
Author(s):  
SRIRAM BS ◽  
RAVICHANDRA V
Keyword(s):  
Experimental Study ◽  
Behavioral Disorders ◽  
Neurotrophic Factor ◽  
Monosodium Glutamate ◽  
Antidepressant Activity ◽  
Brain Derived Neurotrophic Factor ◽  
Control Group ◽  
Male Mice ◽  
Significant Difference

Objective: The objective of the study was to evaluate the antidepressant activity of quercetin in monosodium glutamate (MSG) model of depressed male mice. Methods: MSG was administered (500 mg/kg) to different groups of albino male mice daily for 21 days to induce depression. The interventions (Quercetin and imipramine) were started on day 9th and continued till 21st day. On 23rd day, mice are sacrificed, hippocampus and amygdala supernatant are subjected for analysis. p<0.05 was considered as statistically significant. Results: There was a statistically significant reduction in interleukin (IL)-6 levels in animals treated with quercetin and imipramine compared to control group (p<0.001). There was also a statistically significant increase in brain-derived neurotrophic factor (BDNF) levels in quercetin with MSG groups (p<0.05) and imipramine with MSG groups (p<0.01). There was no statistically significant difference in IL-6 and BDNF levels between the groups of animals treated with quercetin (100 mg/kg) and imipramine (10 mg/kg) alone. Conclusion: Quercetin appeared to have an antidepressant activity. More extensive research is required to substantiate and elucidate the role of quercetin in behavioral disorders such as depression.

scholarly journals Evaluation of antidepressant activity of tramadol in mice: an experimental study

2015 ◽  
pp. 463-468 ◽  
Author(s):  
Vishal Ubale ◽  
Jugalkishore Jaju ◽  
Punam Gosavi ◽  
Ganesh Pawar ◽  
Shrikant Dharmadhikari ◽  
...  
Keyword(s):  
Experimental Study ◽  
Antidepressant Activity

scholarly journals The Antidepressant Activity Of The New Tetrapeptide Neuroprotector Kk-1, Homologous Of Acth15-18 Sequence (An Experimental Study)

2017 ◽  
Vol 1 (3) ◽  
pp. 10-17
Author(s):  
Roman D. Deiko ◽  
Sergiy Yu. Shtrygol ◽  
Alexandr A. Kolobov ◽  
Andrey S Simbirtsev ◽  
Maria V. Mishchenko
Keyword(s):  
Experimental Study ◽  
Antidepressant Activity

Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study

Phytomedicine ◽  
2000 ◽  
Vol 7 (6) ◽  
pp. 463-469 ◽  
Author(s):  
S.K. Bhattacharya ◽  
A. Bhattacharya ◽  
K. Sairam ◽  
S. Ghosal
Keyword(s):  
Experimental Study ◽  
Withania Somnifera ◽  
Antidepressant Activity

scholarly journals Evaluation of antidepressant activity of ondansetron alone and in combination with fluoxetine-an experimental study

2016 ◽  
pp. 90-97
Author(s):  
Sonal Parekar ◽  
Shrikant Dharmadhikari ◽  
Jugalkishore Jaju ◽  
Ganesh Pawar ◽  
Rajvardhan Solunke
Keyword(s):  
Experimental Study ◽  
Antidepressant Activity

Experimental study on the restoration from a tilt-azimuth series for improvement in resolution

1995 ◽  
Vol 53 ◽  
pp. 636-637
Author(s):  
Norio Baba ◽  
Norihiko Ichise ◽  
Syunya Watanabe
Keyword(s):  
Experimental Study ◽  
Spherical Aberration ◽  
Incident Beam ◽  
Optical Parameters ◽  
Beam Tilting ◽  
Illumination Method ◽  
Restoration Method ◽  
Illumination Mode

The tilted beam illumination method is used to improve the resolution comparing with the axial illumination mode. Using this advantage, a restoration method of several tilted beam images covering the full azimuthal range was proposed by Saxton, and experimentally examined. To make this technique more reliable it seems that some practical problems still remain. In this report the restoration was attempted and the problems were considered. In our study, four problems were pointed out for the experiment of the restoration. (1) Accurate beam tilt adjustment to fit the incident beam to the coma-free axis for the symmetrical beam tilting over the full azimuthal range. (2) Accurate measurements of the optical parameters which are necessary to design the restoration filter. Even if the spherical aberration coefficient Cs is known with accuracy and the axial astigmatism is sufficiently compensated, at least the defocus value must be measured. (3) Accurate alignment of the tilt-azimuth series images.

An experimental study in reducing blood pressure in spontaneously hypertensive rats through extracellular signal-regulated kinase inhibition

2010 ◽  
Vol 34 (8) ◽  
pp. S31-S31
Author(s):  
Li Jing ◽  
Jian‑zhong Zhang ◽  
Jin‑ping Sun ◽  
Xin An ◽  
Feng‑ying Guo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Experimental Study ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Kinase Inhibition ◽  
Spontaneously Hypertensive ◽  
Extracellular Signal Regulated Kinase ◽  
Extracellular Signal

An Experimental Study of Some Properties of Stuttered Words

1962 ◽  
Vol 5 (4) ◽  
pp. 387-394 ◽  
Author(s):  
Bruce Quarrington ◽  
Jerome Conway ◽  
Nathan Siegel
Keyword(s):  
Experimental Study
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