scholarly journals Therapeutic effectiveness of Hydroxyapatite Nanoparticles and Pulsed Electromagnetic Field in Osteoporosis and Cancer

2019 ◽  
Vol 8 ◽  
pp. 1058-1072
Author(s):  
Divya Prakash ◽  
Shikha S Chauhan ◽  
Jitendra Behari
Keyword(s):  
Electromagnetic Field ◽  
Ceramic Materials ◽  
Repair Process ◽  
Fracture Repair ◽  
Hydroxyapatite Nanoparticles ◽  
Pulsed Electromagnetic Field ◽  
Carcinoma Cell Lines ◽  
Therapeutic Outcomes ◽  
Pulsed Electromagnetic ◽  
Cancerous Cells

The emergence of nanotechnology has had a profound effect on many areas of healthcare and scientific research. Several studies reported the importance Hydroxyapetite Nanoparticles in the biomedical field in general, and in emerging areas such as implants, drug delivery, cancer, composites, coatings, and ceramic materials in particular. On the other hand, low level Pulsed electromagnetic field (PEMF) therapy presents several potential advantages including non-invasiveness, safety, highly influential in the fracture repair process, lack of toxicity for non-cancerous cells, and the possibility of being combined with other available therapies. It has also been observed that the combined effect of these two can accelerate the osteognic and anticancer activity in the osteoporotic and carcinoma cell lines respectively. The objective of this review is to provide a broad recount of the applications of PEMFs and Hydroxyapatite nanoparticles in osteoporosis and cancer and to then demonstrate what is further required for enhanced therapeutic outcomes.

scholarly journals Pulsed electromagnetic field stimulation may improve fusion rates in cervical arthrodesis in high-risk populations

2018 ◽  
Vol 7 (2) ◽  
pp. 124-130 ◽  
Author(s):  
D. Coric ◽  
D. E. Bullard ◽  
V. V. Patel ◽  
J. T. Ryaby ◽  
B. L. Atkinson ◽  
...  
Keyword(s):  
Electromagnetic Field ◽  
Risk Factor ◽  
High Risk ◽  
Clinical Risk Factor ◽  
Field Stimulation ◽  
Pulsed Electromagnetic Field ◽  
Exact Test ◽  
High Risk Populations ◽  
Pulsed Electromagnetic ◽  
Pemf Treatment

Objectives Pulsed electromagnetic field (PEMF) stimulation was evaluated after anterior cervical discectomy and fusion (ACDF) procedures in a randomized, controlled clinical study performed for United States Food and Drug Administration (FDA) approval. PEMF significantly increased fusion rates at six months, but 12-month fusion outcomes for subjects at elevated risk for pseudoarthrosis were not thoroughly reported. The objective of the current study was to evaluate the effect of PEMF treatment on subjects at increased risk for pseudoarthrosis after ACDF procedures. Methods Two evaluations were performed that compared fusion rates between PEMF stimulation and a historical control (160 subjects) from the FDA investigational device exemption (IDE) study: a post hoc (PH) analysis of high-risk subjects from the FDA study (PH PEMF); and a multicentre, open-label (OL) study consisting of 274 subjects treated with PEMF (OL PEMF). Fisher’s exact test and multivariate logistic regression was used to compare fusion rates between PEMF-treated subjects and historical controls. Results In separate comparisons of PH PEMF and OL PEMF groups to the historical control group, PEMF treatment significantly (p < 0.05, Fisher’s exact test) increased the fusion rate at six and 12 months for certain high-risk subjects who had at least one clinical risk factor of being elderly, a nicotine user, osteoporotic, or diabetic; and for those with at least one clinical risk factor and who received at least a two- or three-level arthrodesis. Conclusion Adjunctive PEMF treatment can be recommended for patients who are at high risk for pseudoarthrosis. Cite this article: D. Coric, D. E. Bullard, V. V. Patel, J. T. Ryaby, B. L. Atkinson, D. He, R. D. Guyer. Pulsed electromagnetic field stimulation may improve fusion rates in cervical arthrodesis in high-risk populations. Bone Joint Res 2018;7:124–130. DOI: 10.1302/2046-3758.72.BJR-2017-0221.R1.

Low-frequency Pulsed Electromagnetic Field Therapy in Fibromyalgia

2009 ◽  
Vol 25 (8) ◽  
pp. 722-728 ◽  
Author(s):  
Serap Tomruk Sutbeyaz ◽  
Nebahat Sezer ◽  
Fusun Koseoglu ◽  
Sibel Kibar
Keyword(s):  
Electromagnetic Field ◽  
Low Frequency ◽  
Pulsed Electromagnetic Field ◽  
Field Therapy ◽  
Pulsed Electromagnetic ◽  
Pulsed Electromagnetic Field Therapy
Sign in / Sign up

Export Citation Format

Share Document