WAIS Results for Ss with Longstanding, Chronic, Lateralized and Diffuse Cerebral Dysfunction

1964 ◽  
Vol 19 (3) ◽  
pp. 735-739 ◽  
Author(s):  
Kathleen B. Fitzhugh ◽  
Loren C. Fitzhugh
Keyword(s):  
Right Hemisphere ◽  
Age Of Onset ◽  
Lesion Group ◽  
Clinical Samples ◽  
Performance Tasks ◽  
Cerebral Dysfunction ◽  
The Mean ◽  
The Right ◽  
Total Performance Scores ◽  
Diffuse Lesion

Several studies utilizing W-B I results have shown differential impairment on verbal or performance tasks associated with lateralized cerebral dysfunction. Only modest differential impairment, however, has been found among patients with longstanding, chronic brain damage. Increased use of the newer scale, the WAIS, warrants evaluation of possible differential impairment of selected clinical samples on this scale. WAIS results were compared for 28 Ss with longstanding maximal cerebral damage of the left hemisphere, 24 with maximal damage of the right hemisphere, and 46 with diffuse damage. Significant differences between group means were rare. However, the mean intra-individual difference between total Verbal and total Performance scores was highly significant for the right-lesion group, moderately significant for the diffuse-lesion group, and non-significant for the left-lesion group. Further investigation with the instrument is needed on groups which differ from those in the present study with respect to variables such as duration of cerebral dysfunction, type of lesion, and age of onset, in order to improve our understanding of relationships between cerebral dysfunction and ability deficits.

Effect of Visual Complexity in Identification of Tachistoscopic Images

1994 ◽  
Vol 78 (3) ◽  
pp. 971-978 ◽  
Author(s):  
Robert Geheb ◽  
Keith E. Whitfield ◽  
Linda Brannon
Keyword(s):  
Reaction Time ◽  
Left Hemisphere ◽  
Right Hemisphere ◽  
Visual Complexity ◽  
Reaction Times ◽  
Right Cerebral Hemisphere ◽  
The Mean ◽  
The Times ◽  
The Right ◽  
Mean Reaction Time

The present study of gender differences in hemispheric processing involved identification of tachistoscopically presented images of varying complexity. A computerized tachistoscopic program was administered to 24 men and 34 women. Time to identify contour and detailed pictures presented to the left or right cerebral hemisphere was recorded. Mean reaction time for contour pictures was significantly faster than for detailed pictures, and mean reaction time to the right hemisphere was significantly faster than that to the left hemisphere. The mean reaction time for men to identify pictures exposed to the left hemisphere was significantly slower than that for exposure to the right hemisphere for women. The mean reaction time for both men and women to identify contour pictures exposed to the right hemisphere was significantly faster than the mean time to identify detailed pictures presented to the left hemisphere. The interaction of gender, hemisphere, and complexity was also significant in that mean reaction times for men to identify detailed pictures presented to the left hemisphere were slower than the times for women to identify contour pictures presented to the right hemisphere. The results are discussed in relation to theories about hemispheres, gender, and differences in picture features.

PRAXIS AND LANGUAGE ORGANIZATION IN LEFT-HANDERS

2020 ◽  
Vol 18 (1) ◽  
pp. 15-28
Author(s):  
Grzegorz Króliczak ◽  
Brian J. Piper ◽  
Weronika Potok ◽  
Mikołaj Buchwald ◽  
Paweł Kleka ◽  
...  
Keyword(s):  
Bimanual Coordination ◽  
Right Hemisphere ◽  
Functional Neuroimaging ◽  
Spatial Processing ◽  
Language Functions ◽  
Attentional Resources ◽  
Neural Processes ◽  
The Mean ◽  
The Right

The performance of learned manual gestures (praxis) and the production of speech are thought to depend on related neural processes. If this relationship is not invoked by an unknown, third variable then shifts in their laterality, including dissociations of these two functions, would be unlikely unless the sharing of some neural resources with other functions is advantageous. This could be the case in lefthanders, in whom actions requiring manual precision are controlled by their right hemispheres, and whose representations could attract the control of skilled gesture. Functional neuroimaging (fMRI) was used to study praxis and language functions. Their lateralization indices were measured in 56 consecutively tested lefthanders (28 females), with the mean age of 23.3±4.9 years (range 18.4 – 47 years), and an Edinburgh Handedness Inventory quotient between –100 and –55.6 (with the mean of –83.8±14.2). We show that atypical, bilateral organization or right-lateralization of praxis is more common than atypical organization/lateralization of language, observed, respectively, in 23 (41%) vs. 15 (26.8%) of cases. Specifically, we found: (a) seven cases (12.5%) of clear, and an additional three cases (5.4%) of less pronounced dissociations of atypically represented praxis from typically represented language; (b) 13 cases (23.2%) with atypically organized praxis also associated with atypically organized language, and (c) only two cases (3.6%) of rather strongly atypical lateralization of language, yet with quite typical lateralization of praxis. These outcomes are consistent with an idea that, in some lefthanders, the guidance of skilled manual actions can profit from tighter links with the right hemisphere, whose motor specialization is linked in this particular population to manual precision, but in general to attentional resources, visuo-spatial processing and even bimanual coordination. Because of the presumed links of praxis with productive language, such transfers are often, and unsurprisingly accompanied by the reorganization of the latter. Yet, the very rare cases of reversed language functions, without any pronounced shifts in representations of praxis, indicate that such a pattern of segregation – or inverse dissociation – of these two functions could be maladaptive.

scholarly journals Hypertrichosis Is Not so Prevalent in Becker's Nevus: Analysis of 47 Cases

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Abbas Rasi ◽  
Hoda Berenji Ardestani ◽  
Seyed Mehdi Tabaie
Keyword(s):  
Age Of Onset ◽  
Skin Inflammation ◽  
The Body ◽  
Brown Patch ◽  
Becker’S Nevus ◽  
The Mean ◽  
The Right

Becker's nevus is a relatively common cutaneous hamartoma, but is often overlooked or misdiagnosed. This nevus usually begins during the second decade of life as a circumscribed, hyperpigmented patch with irregular outline that gradually enlarges with associated hypertrichosis, developing several years later. The purpose of this study was to determine the prevalence of lesional hypertrichosis associated with Becker's nevus. Methods. 47 patients who had sharply demarcated brown patch with or without coarse hair, presence or enlargement of the lesion at the time of puberty, and compatible Wood's light examination were enrolled. Patients who had axillary freckling, previous skin inflammation, and gray pigmentation of the lesions were excluded. Results. In summary, the mean age of onset was 11.89 (range 0–19). The most commonly involved site was the arm (34%), followed by shoulder (23.4%), chest, face, flank, buttock, and leg. Lesional hypertrichosis was found in only 8 (17%) of the 47 patients. In 29 cases (61.7%) the lesions were in the right side of the body. Conclusion. Hypertrichosis was not so frequent among patients with Becker's nevus. There was a higher preponderance of the lesions on the right side.

The abstraction of numerical relations: A role for the right hemisphere in arithmetic?

1997 ◽  
Vol 3 (3) ◽  
pp. 260-268 ◽  
Author(s):  
DAWN W. LANGDON ◽  
ELIZABETH K. WARRINGTON
Keyword(s):  
Right Hemisphere ◽  
Lesion Group ◽  
Reasoning Ability ◽  
Neuropsychological Battery ◽  
Numerical Series ◽  
Cerebral Lesions ◽  
Reasoning Test ◽  
Hemisphere Lesion ◽  
Series Completion ◽  
The Right

Arithmetical reasoning ability has been investigated in a group study of patients with unilateral cerebral lesions. Two series of 38 and 39 patients, who had suffered unilateral cerebral lesions of the right and left cerebral hemisphere, respectively, were investigated. They completed a neuropsychological battery that included a test of computation (Graded Difficulty Arithmetic, GDA; Jackson & Warrington, 1986), and a new test of numerical series completion (Arithmetical Reasoning Test, ART). Whereas the left-hemisphere lesion group were markedly more impaired on the GDA compared to both the right-hemisphere lesion group and a standardization sample, both lesion groups were equally severely impaired on the ART. It is suggested that the abstraction of numerical relations, which is essential to numerical series completion, relies on the integrity of the right hemisphere. A global model of arithmetic processing that incorporates these findings is proposed. (JINS, 1997, 3, 260–268.)

Specialized Cognitive Function and Reading Achievement in Hearing-Impaired Adolescents

1988 ◽  
Vol 53 (1) ◽  
pp. 30-41 ◽  
Author(s):  
Helen B. Craig ◽  
Harold W. Gordon
Keyword(s):  
Cognitive Function ◽  
Reading Achievement ◽  
Right Hemisphere ◽  
Age Of Onset ◽  
Hearing Impaired ◽  
Cognitive Profile ◽  
Visuospatial Skills ◽  
Highly Correlated ◽  
The Right ◽  
Hearing Impaired Students

This study evaluated the performance of hearing-impaired adolescents on tests of specialized cognitive functioning and explored the linkage between cognitive profile and reading achievement. Other variables noted were mathematics achievement, speech production, etiology, and age of onset of hearing loss. Subjects were 62 severely-to-profoundly hearing-impaired students between 15 and 20 years of age, 31 "high readers" and 31 "low readers." Results indicated that, for this sample, cognitive function was below average for the verbal and sequential skills associated with the left hemisphere but above average for the "visuospatial" skills associated with the right hemisphere. Reading performance proved to be highly correlated with cognitive profile, as did mathematics performance and, to a lesser extent, speech and age of onset. Ramifications for instruction are discussed—in particular, development of strategies for using the right hemispheric cognitive strengths, as identified in this sample, to help overcome the deficits in "verbosequential" processing and reading achievement traditionally associated with hearing-impaired students.

scholarly journals The Merging Tracks of Anosognosia and Neglect

2020 ◽  
Vol 83 (4) ◽  
pp. 438-446
Author(s):  
Karen G. Langer ◽  
Julien Bogousslavsky
Keyword(s):  
Mental Representation ◽  
Right Hemisphere ◽  
Perceptual Processing ◽  
Extrapersonal Space ◽  
Cerebral Dysfunction ◽  
The Right ◽  
Altered Awareness ◽  
Corporeal Awareness ◽  
Apparent Resistance

Anosognosia and hemineglect are among the most startling neurological phenomena identified during the 20th century. Though both are associated with right hemisphere cerebral dysfunction, notably stroke, each disorder had its own distinct literature. Anosognosia, as coined by Babinski in 1914, describes patients who seem to have no idea of their paralysis, despite general cognitive preservation. Certain patients seem more than unaware, with apparent resistance to awareness. More extreme, and qualitatively distinct, is denial of hemiplegia. Various interpretations of pathogenesis are still deliberated. As accounts of its captivating manifestations grew, anosognosia was established as a prominent symbol of neurological and psychic disturbance accompanying (right-hemisphere) stroke. Although reports of specific neglect-related symptomatology appeared earlier, not until nearly 2 decades after anosognosia’s inaugural definition was neglect formally defined by Brain, paving a path spanning some years, to depict a class of disorder with heterogeneous variants. Disordered awareness of body and extrapersonal space with right parietal lesions, and other symptom variations, were gathered under the canopy of neglect. Viewed as a disorder of corporeal awareness, explanatory interpretations involve mechanisms of extinction and perceptual processing, disturbance of spatial attention, and others. Odd alterations involving apparent concern, attitudes, or belief characterize many right hemisphere conditions. Anosognosia and neglect are re-examined, from the perspective of unawareness, the nature of belief, and its baffling distortions. Conceptual parallels between these 2 distinct disorders emerge, as the major role of the right hemisphere in mental representation of self is highlighted by its most fascinating syndromes of altered awareness.

scholarly journals Clinical and genetic characteristics of 14 patients from 13 Japanese families with RPGR-associated retinal disorder: report of eight novel variants

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Go Mawatari ◽  
◽  
Kaoru Fujinami ◽  
Xiao Liu ◽  
Lizhu Yang ◽  
...  
Keyword(s):  
Retinitis Pigmentosa ◽  
Japanese Population ◽  
Age Of Onset ◽  
Genetic Characteristics ◽  
Therapeutic Trials ◽  
Novel Variants ◽  
Genetic Features ◽  
The Mean ◽  
The Right ◽  
Retinal Disorder

AbstractVariants in the retinitis pigmentosa GTPase regulator (RPGR) gene are a major cause of X-linked inherited retinal disorder (IRD). We herein describe the clinical and genetic features of 14 patients from 13 Japanese families harboring RPGR variants in a nationwide cohort. Comprehensive ophthalmological examinations were performed to classify the patients into one of the phenotype subgroups: retinitis pigmentosa (RP) and cone rod dystrophy (CORD). The mean age of onset/at examination was 13.8/38.1 years (range, 0–50/11–72), respectively. The mean visual acuity in the right/left eye was 0.43/0.43 (range, 0.1–1.7/−0.08–1.52) LogMAR unit. Eight patients had RP, and six had CORD. Whole-exome sequencing with target analyses identified 13 RPGR variants in 730 families with IRD, including 8 novel variants. An association between the phenotype subgroup and the position of variants (cutoff of amino acid 950) was revealed. To conclude, the clinical and genetic spectrum of RPGR-associated retinal disorder was first illustrated in a Japanese population, with a high proportion of novel variants. These results suggest the distinct genetic background of RPGR in the Japanese population, in which the genotype–phenotype association was affirmed. This evidence should be helpful monitoring and counseling patients and in selecting patients for future therapeutic trials.

scholarly journals The Influence of Sex on Navigating Acute Coronary Syndrome: A Hospital-Based Cohort Study in South Asia

2021 ◽  
Author(s):  
Udaya Ralapanawa ◽  
Parackrama Karunathilake ◽  
Charith Bandara ◽  
Prabhashini Kumarihamy ◽  
Sujeewa Gunaratne ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Unstable Angina ◽  
Alcohol Intake ◽  
Age Of Onset ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
Predominant Symptom ◽  
The Mean ◽  
The Right

Abstract BackgroundThe cardiovascular risk profile and adverse events following acute coronary syndrome (ACS) differ between the Sex, indicating the importance of studying the sex differences in factors associated with ACS.MethodsA cross-sectional descriptive study was performed among ACS patients presented to Teaching Hospital Peradeniya. An interviewer-administered prevalidated questionnaire was used to collect data, and analysis was done. ResultsA total of 789 patients were included, consisting of 40.4% females. The mean age of females (62.17±11.06) was higher than males (59.80±11.24) (p=0.004), and in females, the mean age for unstable angina (60.5±10.5) was lower than NSTEMI (63.8±12.5) (p=0.022) and STEMI (64.0±9.2) (p=0.026). The male-female composition for unstable angina (46.3% vs 53.7%) and STEMI (75.8% vs 24.2%) showed varied proportions. The mean BMI (24.95±4.40 kg m-3 vs 23.77±3.88 kg m-3) (p=0.008) and obesity (21.6% vs 13.8%) (p=0.048) was higher in females. Overweight (9.4% vs 8.8%) (p=0.048) and the waist-hip ratio (0.98±0.07 vs 0.94±0.10) (p=0.006) was higher in males. Family history of hypertension was higher in females (24.1% vs 17.0%) (p=0.014). Most of the females were co-morbid with diabetes (37.9%) (p=0.008), hypertension (59.8%) (p<0.001) and dyslipidaemia (40.3%) (p<0.001) than males. The prevalence of smoking and alcohol intake was significantly higher in males (p<0.001). The predominant symptom was chest pain (93.4%), regardless of Sex. Right chest pain was primarily present in females (8.0% vs 3.6%) (p=048), and radiation of pain to the right arm mainly occurred in males (18.2% vs 7.5%) (p=0.007). Vomiting and dyspnoea was higher in females (47.7% vs 38.4%, p=0.049 and 53.1% vs 43.2%, p=0.039). The delay in presentation to the hospital was more in females (6:04±6:02) than males (3:55±4:22) with STEMI. The commonest reason for the delay was not suspecting an ACS, and a three-wheeler was the primary mode of transport in both sexes without any sex difference. Only 7.0% was delayed due to the unavailability of a transport facility.ConclusionFemale and male patients with ACS show differences in the age of onset, the spectrum of ACS, comorbidities, anthropometric measurements, risk factors like smoking and alcohol intake, clinical presentation aspects and delay in presentation to the hospital.

Investigation of the Effect of Mode and Tempo on Emotional Responses to Music Using EEG Power Asymmetry

2013 ◽  
Vol 27 (3) ◽  
pp. 142-148 ◽  
Author(s):  
Konstantinos Trochidis ◽  
Emmanuel Bigand
Keyword(s):  
Left Hemisphere ◽  
Right Hemisphere ◽  
Emotional Responses ◽  
Interactive Effects ◽  
Eeg Activity ◽  
Musical Excerpt ◽  
Major Mode ◽  
Musical Modes ◽  
Slow Tempo ◽  
The Right

The combined interactions of mode and tempo on emotional responses to music were investigated using both self-reports and electroencephalogram (EEG) activity. A musical excerpt was performed in three different modes and tempi. Participants rated the emotional content of the resulting nine stimuli and their EEG activity was recorded. Musical modes influence the valence of emotion with major mode being evaluated happier and more serene, than minor and locrian modes. In EEG frontal activity, major mode was associated with an increased alpha activation in the left hemisphere compared to minor and locrian modes, which, in turn, induced increased activation in the right hemisphere. The tempo modulates the arousal value of emotion with faster tempi associated with stronger feeling of happiness and anger and this effect is associated in EEG with an increase of frontal activation in the left hemisphere. By contrast, slow tempo induced decreased frontal activation in the left hemisphere. Some interactive effects were found between mode and tempo: An increase of tempo modulated the emotion differently depending on the mode of the piece.

Right-Hemisphere Specialization for Contour Grouping

2014 ◽  
Vol 61 (5) ◽  
pp. 331-339 ◽  
Author(s):  
Gregor Volberg
Keyword(s):  
Right Hemisphere ◽  
Contour Detection ◽  
Global Processing ◽  
Detection Accuracy ◽  
Frequency Spectra ◽  
Visual Hemifield ◽  
Spatial Frequencies ◽  
A Chain ◽  
The Right ◽  
Hemisphere Specialization

Previous studies often revealed a right-hemisphere specialization for processing the global level of compound visual stimuli. Here we explore whether a similar specialization exists for the detection of intersected contours defined by a chain of local elements. Subjects were presented with arrays of randomly oriented Gabor patches that could contain a global path of collinearly arranged elements in the left or in the right visual hemifield. As expected, the detection accuracy was higher for contours presented to the left visual field/right hemisphere. This difference was absent in two control conditions where the smoothness of the contour was decreased. The results demonstrate that the contour detection, often considered to be driven by lateral coactivation in primary visual cortex, relies on higher-level visual representations that differ between the hemispheres. Furthermore, because contour and non-contour stimuli had the same spatial frequency spectra, the results challenge the view that the right-hemisphere advantage in global processing depends on a specialization for processing low spatial frequencies.

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