Stimuli Associated with Pregnancy Prepare for Maternal Behavior in Rats

1978 ◽  
Vol 43 (3_suppl) ◽  
pp. 1175-1182 ◽  
Author(s):  
Celia L. Moore ◽  
Gilda A. Morelli
Keyword(s):  
Social Isolation ◽  
Maternal Behavior ◽  
Initial Response ◽  
Female Rats ◽  
Pregnant Females ◽  
Time Required

Cohabitation with pregnant females decreased the time required for reproductively naive female rats to become maternal with constant stimulation by pups. Experience with a companion's parturition did not add to experience related to her pregnancy. Exposure to pregnancy-related stimuli also increased nestbuilding as an initial response of virgins to pups. Social isolation for 9 days before exposure to pups decreased both contact with pups and cannibalism.

Social isolation prompts maternal behavior in sexually naïve male ddN mice

2015 ◽  
Vol 151 ◽  
pp. 9-15 ◽  
Author(s):  
Chitose Orikasa ◽  
Kentaro Nagaoka ◽  
Harumi Katsumata ◽  
Manami Sato ◽  
Yasuhiko Kondo ◽  
...  
Keyword(s):  
Social Isolation ◽  
Maternal Behavior

Adrenal inhibition of maternal behavior in virgin female rats

1975 ◽  
Vol 6 (2) ◽  
pp. 165-171 ◽  
Author(s):  
Michael Leon ◽  
Michael Numan ◽  
Allan Chan
Keyword(s):  
Maternal Behavior ◽  
Virgin Female ◽  
Female Rats

Maternal Behavior in the Rat: an Investigation and Quantification of Nest Building

Behaviour ◽  
1969 ◽  
Vol 34 (1-2) ◽  
pp. 1-16 ◽  
Author(s):  
Victor H. Denenberg ◽  
M.X. Zarrow ◽  
Rhoda E. Taylor
Keyword(s):  
Maternal Behavior ◽  
Nest Building ◽  
Significant Finding ◽  
Nest Material ◽  
Warm Temperature ◽  
Ambient Temperatures ◽  
Pregnant Females ◽  
Series Of Experiments ◽  
Similarities And Differences ◽  
Over Time

AbstractA technique has been developed to quantify nest building in rats. Small wooden dowels are provided as nest material. Rats shred the dowels, and the degree of nest building is determined by the amount shredded daily. Pregnant females show a marked increase in dowel shredding at or just prior to the time of parturition; shredding falls precipitously after parturition. Males and nonpregnant females show no such pattern over an equivalent period of time; their dowel shredding, in fact, decreases over time. A series of experiments were carried out involving hormone manipulations of pregnant and nonpregnant females. The only significant finding was that progesterone reduced the percentage of females which shredded dowels and also delayed the time of onset of this behavior. When nonpregnant females and males were exposed to cool ambient temperatures, dowel shredding increased markedly. On the other hand, exposing females to a warm temperature blocked dowel shredding behavior. Some similarities and differences between these findings and findings for the rabbit and mouse are discussed.

Excitotoxic Amino Acid Injections into the Medial Amygdala Facilitate Maternal Behavior in Virgin Female Rats

1993 ◽  
Vol 27 (1) ◽  
pp. 56-81 ◽  
Author(s):  
Michael Numan ◽  
Marilyn J. Numan ◽  
Jeffrey B. English
Keyword(s):  
Amino Acid ◽  
Maternal Behavior ◽  
Virgin Female ◽  
Female Rats ◽  
Medial Amygdala

scholarly journals Social isolation rearing-induced anxiety and response to agomelatine in male and female rats: Role of corticosterone, oxytocin, and vasopressin

2019 ◽  
Vol 33 (5) ◽  
pp. 640-646 ◽  
Author(s):  
Brian H Harvey ◽  
Wilmie Regenass ◽  
Walter Dreyer ◽  
Marisa Möller
Keyword(s):  
Social Isolation ◽  
Female Rats ◽  
Male Rats ◽  
Isolation Rearing ◽  
Male And Female ◽  
Plasma Vasopressin ◽  
Male And Female Rats ◽  
Plus Maze ◽  
Circadian Fluctuation ◽  
Social Isolation Rearing

Background: The chronobiotic antidepressant, agomelatine, acts via re-entrainment of circadian rhythms. Earlier work has demonstrated late-life anxiety and reduced corticosterone in post-weaning social isolation reared (SIR) rats. Agomelatine was anxiolytic in this model but did not reverse hypocortisolemia. Reduced corticosterone or cortisol (in humans) is well-described in anxiety states, although the anxiolytic-like actions of agomelatine may involve targeting another mechanism. Central oxytocin and vasopressin exert anxiolytic and anxiogenic effects, respectively, and are subject to circadian fluctuation, while also showing sex-dependent differences in response to various challenges. Aims and methods: If corticosterone is less involved in the anxiolytic-like actions of agomelatine in SIR rats, we wondered whether effects on vasopressin and oxytocin may mediate these actions, and whether sex-dependent effects are evident. Anxiety as assessed in the elevated plus maze, as well as plasma vasopressin, oxytocin, and corticosterone were analyzed in social vs SIR animals receiving sub-chronic treatment with vehicle or agomelatine (40 mg/kg/day intraperitoneally at 16:00) for 16 days. Results: Social isolation rearing induced significant anxiety together with increased plasma vasopressin levels, but decreased corticosterone and oxytocin. While corticosterone displayed sex-dependent changes, vasopressin, and oxytocin changes were independent of sex. Agomelatine suppressed anxiety as well as reversed elevated vasopressin in both male and female rats and partially reversed reduced oxytocin in female but not male rats. Conclusion: SIR-associated anxiety later in life involves reduced corticosterone and oxytocin, and elevated vasopressin. The anxiolytic-like effects of agomelatine in SIR rats predominantly involve targeting of elevated vasopressin.

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