scholarly journals Markers of Atherosclerosis in Hypertensive Patients with Less Advanced Chronic Kidney Disease

2019 ◽  
Vol 65 (3) ◽  
pp. 91-96
Author(s):  
Claudia Floriana Suciu ◽  
Andreea Varga ◽  
Corneliu Florin Buicu ◽  
Ioan Tilea
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Aortic Arch ◽  
Laboratory Data ◽  
Hypertensive Heart Disease ◽  
Neutrophil To Lymphocyte Ratio ◽  
Advanced Chronic Kidney Disease ◽  
Hypertensive Patients ◽  
Lymphocyte Ratio ◽  
Aortic Arch Calcification

AbstractObjective: Our study aimed to validate the neutrophil-to-lymphocyte ratio (NLR) as a marker for aortic arch calcification in hypertensive patients with less advanced chronic kidney disease (CKD).Methods: A number of forty-four hypertensive patients with chronic kidney disease (categories G3a and G3b – 2012 KDIGO nomenclature) were included in the study. Considering the presence of aortic arch calcification (AAC) on chest X-ray, the study population was divided into two groups: 27 patients AAC present and seventeen without aortic arch calcification. Laboratory data were collected for each patient and NLR was computed. Comorbidities were also recorded: stable coronary artery disease, lower extremity arterial disease and hypertensive heart disease.Results: A positive correlation between neutrophil-to-lymphocyte ratio and aortic arch calcification in hypertensive CKD patients was identified. Furthermore, advanced age, increased alkaline phosphatase and increased erythrocyte sedimentation rate had a positive association with aortic arch calcification. We found no statistical correlation between neutrophil-to-lymphocyte ratio and other laboratory features in both groups of patients.Conclusions: Neutrophil-to-lymphocyte ratio may be viewed as a potential risk factor for vascular calcification in patients with moderate chronic kidney disease; nevertheless, future extensive studies are necessary. In the management of hypertensive patients, general medicine might particularly benefit of this simple, readily available inflammatory marker.

scholarly journals Aortic arch calcification in hypertensive patients with chronic kidney disease

2019 ◽  
Vol 15 (2) ◽  
pp. 182-187
Author(s):  
Claudia Floriana Suciu ◽  
◽  
Andreea Varga ◽  
Corneliu Florin Buicu ◽  
Valeria Herdea ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Aortic Arch ◽  
Hypertensive Patients ◽  
Aortic Arch Calcification

scholarly journals Aortic Arch Calcification Predicts the Renal Function Progression in Patients with Stage 3 to 5 Chronic Kidney Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Lung-Chih Li ◽  
Yueh-Ting Lee ◽  
Yi-Wei Lee ◽  
Chia-An Chou ◽  
Chien-Te Lee
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Aortic Arch ◽  
Estimated Glomerular Filtration Rate ◽  
X Ray ◽  
Chest X Ray ◽  
Independent Determinant ◽  
Egfr Decline ◽  
Aortic Arch Calcification

Introduction. The presence of aortic arch calcification (AoAC) and cardiomegaly on chest radiography has been demonstrated as important risk factors for cardiovascular mortality in patients with chronic kidney disease (CKD). However, the interrelationship among AoAC, cardiomegaly, and renal function progression remains unclear. The aim of this study is to assess whether AoAC and cardiomegaly are independently associated with the renal function progression in patients with stages 3–5 CKD.Methods. We retrospectively determined AoAC and cardiomegaly by chest X-ray in 237 patients, followed up for at least three years without entering dialysis and classified into 4 groups according to the presence or absence of AoAC and cardiomegaly. The change in renal function was measured by the slope of estimated glomerular filtration rate (eGFR).Results. Of the 237 patients, the rate of eGFR decline was significantly higher in the group with coexistence of AoAC and cardiomegaly than any other groups. Baseline AoAC and proteinuria were independently associated with eGFR decline. AoAC were independently determined by age, eGFR slope, and cardiomegaly.Conclusions. The coexistence of AoAC and cardiomegaly is associated with faster eGFR decline. AoAC is an independent determinant of renal outcomes in patients with CKD stages 3–5.

scholarly journals Pathological Findings in Chest Radiographs of Chronic Kidney Disease Patients Undergoing Hemodialysis

2021 ◽  
Vol 4 (1) ◽  
pp. 38-45
Author(s):  
Siti Nurhayati Utami ◽  
Hanna Marsinta Uli ◽  
Indri Seta Septadina
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Pleural Effusion ◽  
Kidney Disease ◽  
Pulmonary Edema ◽  
Aortic Arch ◽  
Medical Records ◽  
Chest Radiographs ◽  
Age Range ◽  
Aortic Arch Calcification

Chronic kidney disease is a condition in which there is destruction of the kidneys along with structural or functional abnormalities, with or without decreased glomerular filtration rate for more than 3 months. The common treatment for this condition is hemodialysis, however, it may cause complications, specifically cardiovascular and non-cardiovascular system dysfunctions that can be observed through thorax imaging. This study aims to observe pathologic thorax imaging findings on chronic kidney disease patients undergoing hemodialysis at RSUP Dr. Mohammad Hoesin Palembang. This study is a descriptive study using a cross-sectional design. The data is gathered from medical records from the Medical Records & Radiology Department of RSUP Dr. Mohammad Hoesin Palembang that have passed the inclusion and exclusion criteria. The data is processed using the SPSS application version 25. The results of this study indicate that, based on risk factors, patients are generally in the 55-64 age range (41%), female (60%), and with a normal BMI/normal weight (52%). Based on the patients’ comorbid diseases, patients mostly have hypertension (59%), followed by diabetes mellitus (46%). Analysis of the chest radiographs indicate that (70%) of patients have cardiomegaly; (22%) of patients have grade 1, (15%) have grade 2, (7%) have grade 3 aortic arch calcification; (49%) have pulmonary edema; (31%) have unilateral pleural effusion, and (14%) have bilateral pleural effusion.  The majority of chronic kidney disease patients undergoing hemodialysis at RSUP Dr. Mohammad Hoesin Palembang are in the 55-64 age range, female, and with normal BMI. The most common comorbid conditions are hypertension and diabetes mellitus. Analysis of the chest radiographs indicate that the majority of patients have cardiomegaly; grade 1, 2, and 3 aortic arch calcification; pulmonary edema; unilateral and bilateral pleural effusion.

Plasma microRNA-126-3p and neutrophil-to-lymphocyte ratio in patients with chronic kidney disease: relationships to ambulatory 24-h blood pressure

2019 ◽  
Vol 34 (3) ◽  
pp. 248-257
Author(s):  
Dominika Klimczak-Tomaniak ◽  
Tomasz Pilecki ◽  
Dorota Żochowska ◽  
Damian Sieńko ◽  
Maciej Janiszewski ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Plasma Microrna
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