scholarly journals Rare Laryngeal Kaposi’s Sarcoma: Case Report and Innovative Surgical Approach

2019 ◽  
Vol 25 (4) ◽  
pp. 207-213
Author(s):  
Popescu Bogdan ◽  
Oancea Alina Lavinia Antoaneta ◽  
Androne Roxana Gabriela ◽  
Arjoca Elena Mihaela ◽  
Berteșteanu Serban Victor Gabriel

Abstract Kaposi’s sarcoma is an angioproliferative neoplasm that usually appears on the skin, but can also involve all organs and anatomic locations. The atypical manifestations of Kaposi’s sarcoma can mislead the diagnosis, which can result in a poor case management. The authors present a HIV-negative patient with Kaposi’s sarcoma with both usual and unusual locations such as the larynx, eyelids and bones. In the pre-therapeutic balance, we used NBI, which showed an intensely vascularized tumor in the larynx. The chosen method for treatment consisted in subtotal epiglotectomy performed under TransOral UltraSonic Surgery (TOUSS) approach. The use of TOUSS endoscopic surgery helped reduce the time of hospitalization, the patient did not need a nasogastric tube and was orally fed from the first postoperative day, with a better and faster functional recovery.

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Sofia Baina ◽  
Jihane Achrane ◽  
Jouda Benamor ◽  
Jamal Eddine Bourkadi

Kaposi’s Sarcoma (KS) occurs as a pathological entity that may be classified into four different types: classic, endemic, epidemic, and iatrogenic. It can arise among HIV-positive subjects or within immunosuppression, yet exceptionally of tuberculous origin. We describe a new case report of an HIV-negative patient, manifesting Kaposi’s disease in the course of tuberculosis, with the aim to assess this uncommon disorder and to outline this rare atypical association.


2018 ◽  
Vol 44 (2) ◽  
pp. 182-184 ◽  
Author(s):  
Mustafa Gurkan Yenice ◽  
Esra Varnali ◽  
Kamil Gokhan Seker ◽  
Ayse Kavak ◽  
Volkan Tugcu

2020 ◽  
Vol 37 ◽  
Author(s):  
Zeineb Naimi ◽  
Khalil Mahjoubi ◽  
Olfa Adouni ◽  
Rim Abidi ◽  
Maha Driss ◽  
...  

Pathology ◽  
2014 ◽  
Vol 46 ◽  
pp. S139
Author(s):  
Adelina Birceanu-Corobea ◽  
Monica Gratiela Hortopan ◽  
Maria Victoria Comanescu ◽  
Vlad Herlea ◽  
Mihaela Banica ◽  
...  

2016 ◽  
Vol 22 (12) ◽  
Author(s):  
Shields Callahan ◽  
Randie H Kim ◽  
Nooshin Brinster ◽  
Jo-Ann Latkowski

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Ela A. Server ◽  
Yusuf M. Durna ◽  
Ozgur Yigit ◽  
Erol R. Bozkurt

This paper presents a case report of an HIV-negative, supraglottic Kaposi’s sarcoma patient. The 80-year-old male patient was admitted with complaints of hoarseness, difficulty in swallowing, and a stinging sensation in his throat for approximately six months. The endoscopic larynx examination revealed a lesion which had completely infiltrated the epiglottis, reached right aryepiglottic fold, was vegetating, pink and purple in color, multilobular, fragile, and shaped like a bunch of grapes, and partially blocked the bleeding airway passage. The case was discussed by the hospital’s head-neck cancer committee and a surgery decision was made. A tracheotomy was performed under local anesthesia before the operation due to respiratory distress and endotracheal intubation difficulty. Direct laryngoscopy showed that the mass was limited in the supraglottic area, had invaded the entire left aryepiglottic fold and one-third of the front right aryepiglottic fold, and completely covered epiglottis. It should be remembered that although rare, Kaposi’s sarcoma may be encountered in larynx malignancy cases. Disease-free survival may be achieved through local excision and postoperative radiotherapy.


2019 ◽  
Vol 26 (2) ◽  
pp. 133-149
Author(s):  
Michele Bisceglia ◽  
Elena Minenna ◽  
Andrea Altobella ◽  
Francesca Sanguedolce ◽  
Gaetano Panniello ◽  
...  

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 4970-4970
Author(s):  
Anuradha Avinash Belur ◽  
Arun Kumar Arumugam Raajasekar ◽  
Srikant Nannapaneni ◽  
Thandavababu Chelliah

Abstract Case Description: - A 76 year old lady was diagnosed with Chronic Lymphocytic Leukemia (CLL) with 11 q deletion after she presented with generalized lymphadenopathy and anemia. She was treated with rituximab 375mg/m2 day1 and bendamustine 60mg/m2 on day 1 and day 2 and completed six cycles of treatment. After the sixth cycle she developed multiple itchy, papular lesions with bleeding on both lower extremities. She was evaluated multiple times by vascular surgery and dermatology without a definitive diagnosis. She underwent a biopsy with staining for HHV-8, CD31 and CD34 which was positive confirming the diagnosis of Kaposi sarcoma. ELISA test for HIV was negative. She was started on treatment with Doxorubicin 20 mg/m2every 3 weeks and with 3 cycles there was significant regression of the lesions. Discussion-: We describe a case of CLL which was initially started on treatment with rituximab and bendamustine. She tolerated the treatment well, but a few months later presented with skin lesions which on biopsy was diagnosed as Kaposi sarcoma. It is very uncommon for Kaposi sarcoma to develop in a HIV negative patient. This patient was immunocompromised with recent chemotherapy. Rituximab specifically depletes B cells and leads to impaired T cell mediated immunity. This case illustrates the importance of a high index of suspicion in patients treated with rituximab as it is used for a number of hematologic malignancies like leukemia, lymphoma as well as non-malignant conditions like autoimmune disorders. While infusion reactions and reactivation of hepatitis B are side effects physicians are aware of and cautious of while using rituximab, Kaposi’s Sarcoma remains a less known side effect. Awareness of this possibility is important in physicians prescribing rituximab. Footnotes * Asterisk with author names denotes non-ASH members. Disclosures No relevant conflicts of interest to declare.


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