scholarly journals Design of a drop-in EBI sensor probe for abnormal tissue detection in minimally invasive surgery

2020 ◽  
Vol 11 (1) ◽  
pp. 87-95
Author(s):  
Guanming Zhu ◽  
Liang Zhou ◽  
Shilong Wang ◽  
Pengjie Lin ◽  
Jing Guo ◽  
...  
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Resection Margin ◽  
Ex Vivo ◽  
Porcine Liver ◽  
Normal Tissues ◽  
Electrical Bioimpedance ◽  
Sensor Probe ◽  
Abnormal Tissue

AbstractIt is a common challenge for the surgeon to detect pathological tissues and determine the resection margin during a minimally invasive surgery. In this study, we present a drop-in sensor probe based on the electrical bioimpedance spectroscopic technology, which can be grasped by a laparoscopic forceps and controlled by the surgeon to inspect suspicious tissue area conveniently. The probe is designed with an optimized electrode and a suitable shape specifically for Minimally Invasive Surgery (MIS). Subsequently, a series of ex vivo experiments are carried out with porcine liver tissue for feasibility validation. During the experiments, impedance measured at frequencies from 1 kHz to 2 MHz are collected on both normal tissues and water soaked tissue. In addition, classifiers based on discriminant analysis are developed. The result of the experiment indicate that the sensor probe can be used to measure the impedance of the tissue easily and the developed tissue classifier achieved accuracy of 80% and 100% respectively.

scholarly journals Analyzing Liver Surface Indentation for In Vivo Refinement of Tumor Location in Minimally Invasive Surgery

2020 ◽  
Author(s):  
Yingqiao Yang ◽  
Kai-Leung Yung ◽  
Tin Wai Robert Hung ◽  
Kai-Ming Yu
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Surface Deformation ◽  
Angular Position ◽  
Radial Distance ◽  
Tumor Location ◽  
Porcine Liver ◽  
Optimal Material

AbstractManual palpation to update the position of subsurface tumor(s) is a normal practice in open surgery, but is not possible through the small incisions of minimally invasive surgery (MIS). This paper proposes a method that has the potential to use a simple constant-force indenter and the existing laparoscopic camera for tumor location refinement in MIS. The indenter floats with organ movement to generate a static surface deformation on the soft tissue, resolving problems of previous studies that require complicated measurement of force and displacement during indentation. By analyzing the deformation profile, we can intraoperatively update the tumor’s location in real-time. Indentation experiments were conducted on healthy and “diseased” porcine liver specimens to obtain the deformation surrounding the indenter site. An inverse finite element (FE) algorithm was developed to determine the optimal material parameters of the healthy liver tissue. With these parameters, a computational model of tumorous tissue was constructed to quantitatively evaluate the effects of the tumor location on the induced deformation. By relating the experimental data from the “diseased” liver specimen to the computational results, we estimated the radial distance between the tumor and the indenter, as well as the angular position of the tumor relative to the indenter.

scholarly journals Teaching Training and Surgical Education in Minimally Invasive Surgery (MIS) of the Spine: What Are the Best Teaching and Learning Strategies for MIS? Do We Have Any Experience and Data?

2020 ◽  
Vol 10 (2_suppl) ◽  
pp. 126S-129S
Author(s):  
Asdrubal Falavigna ◽  
Alfredo Guiroy ◽  
Néstor Taboada
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Learning Strategies ◽  
Invasive Surgery ◽  
Teaching And Learning ◽  
New Technologies ◽  
Ex Vivo ◽  
Morbidity Rate ◽  
Invasive Techniques

Study Design: Literature review and transversal study. Objective: Advances in new technologies give the surgeons confidence to manage complex spine conditions with a lower morbidity rate. This has changed the expectations of patients and medical payers and foreshadows the shift now underway: the use of minimally invasive techniques. The ethical considerations of learning directly on patients require a change in the education and training programs. Methods: The education paradigm has changed, and surgical training on minimally invasive surgery of the spine (MISS) techniques should follow a “curriculum.” The assessment of skill proficiency while learning the MISS techniques must be measurable to objectively show the performance gained over time and the changes that should be performed during training. Different strategies include “ex vivo” and “in vivo” training. Results: We have worked on a curriculum in which the participants can perceive the growth in their knowledge through the different educational opportunities. There are 3 levels: basic, advanced, and masters. Conclusions: We developed an educational curriculum for MISS rationale and techniques, that showed to be effective and interesting in our region.

scholarly journals Ex vivo study of prostate cancer localization using rolling mechanical imaging towards minimally invasive surgery

2017 ◽  
Vol 43 ◽  
pp. 112-117 ◽  
Author(s):  
Jichun Li ◽  
Hongbin Liu ◽  
Matthew Brown ◽  
Pardeep Kumar ◽  
Benjamin J Challacombe ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Ex Vivo ◽  
Ex Vivo Study ◽  
Mechanical Imaging

scholarly journals Mass spectrometry transanal minimally invasive surgery (MS-TAMIS) to promote organ preservation in rectal cancer

2019 ◽  
Vol 34 (8) ◽  
pp. 3618-3625 ◽  
Author(s):  
Sam Mason ◽  
Eftychios Manoli ◽  
Liam Poynter ◽  
James Alexander ◽  
Petra Paizs ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Rectal Cancer ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Relative Abundance ◽  
Invasive Surgery ◽  
Organ Preservation ◽  
Ex Vivo ◽  
Transanal Minimally Invasive Surgery

Abstract Background Transanal minimally invasive surgery (TAMIS) is deployed for organ preservation in early rectal cancer and significant rectal polyps. Rapid evaporative ionisation mass spectrometry (REIMS) provides biochemical tissue analysis, which could be applied intraoperatively to give real-time tissue feedback to the surgeon and decrease the risk of an involved margin. However, the accuracy and feasibility of this approach have not been established. Methods In this prospective observational study, patients undergoing resection of rectal adenomas or carcinomas were recruited. An electrosurgical handpiece analysed tissues ex vivo using diathermy, with the aerosol aspirated into a Xevo G2-S ToF mass spectrometer. The relative abundance of lipids underwent predictive statistical modelling and leave-one-patient-out cross-validation. The outcomes of interest were the ability of REIMS to differentiate normal, adenomatous and cancerous tissue, or any disease subtype from normal. REIMS was coupled with TAMIS for in vivo sampling, assessing the accuracy of tissue recognition and distinguishing bowel wall layers. Results Forty-seven patients were included, yielding 266 spectra (121 normal, 109 tumour and 36 adenoma). REIMS differentiates normal, adenomatous and cancerous rectal tissues with 86.8% accuracy, and normal and adenomatous tissue with 92.4% accuracy and 91.4% accuracy when differentiating disease from normal. We have performed the first five in-man mass spectrometry augmented TAMIS (MS-TAMIS). In real time, MS-TAMIS can differentiate rectal mucosa and submucosa based on their relative abundance of triglycerides and glycerophospholipids. The ex vivo accuracy distinguishing diseased and normal tissues is maintained in vivo at 90%, with negative predictive value of 95%. The system identified a deep and lateral involved tumour margin during TAMIS. Conclusions REIMS distinguishes rectal tissue types based on underlying lipid biology, and this can be translated in vivo by coupling it to TAMIS. There is a role for this technology in improving the efficacy of resection of early rectal cancers.

scholarly journals A Reproducible Ex Vivo Model for Transanal Minimally Invasive Surgery

2014 ◽  
Vol 18 (1) ◽  
pp. 62-65 ◽  
Author(s):  
Michael Larone Campbell ◽  
Kimberly J. Vadas ◽  
Sowsan H. Rasheid ◽  
Jorge E. Marcet ◽  
Jaime E. Sanchez
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Ex Vivo ◽  
Transanal Minimally Invasive Surgery ◽  
Ex Vivo Model

V1695: Minimizing Minimally Invasive Surgery: the Three Port Robotic Pyeloplasty

2004 ◽  
Vol 171 (4S) ◽  
pp. 448-448
Author(s):  
Farjaad M. Siddiq ◽  
Patrick Villicana ◽  
Raymond J. Leveillee
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Robotic Pyeloplasty
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