The major clinical outcomes of diabetic foot infections: One center experience

Open Medicine ◽  
2008 ◽  
Vol 3 (4) ◽  
pp. 464-469 ◽  
Author(s):  
Adem Ozkara ◽  
Tuncay Delibası ◽  
Yusuf Selcoki ◽  
Mehmet Fettah Arikan

AbstractDiabetes mellitus with its limb and life-threatening complications such as diabetic foot infection and amputation are increasing at epidemic rates all over the world. The objective of this study was to determine the rate of lower extremity amputation, the risk factors and the bacteriologic profile for diabetic foot lesions. The records of all 84 patients with diabetic foot infections of a large general hospital over a 4-year period were retrospectively included. The most commonly isolated pathogens were Staphylococcus aureus (39%), Pseudomonas aeruginosa (14%), Proteus mirabilis (14%), Escherichia coli (14%), Group B streptococci (12%), and Klebsiella pneumonia (8%). The variables, independently associated with higher foot infections, were inadequate diabetic regulation (93%), peripheral neuropathy (88.1%), peripheral vascular disease (73.8%), smoking (56%), past history of ulcer (28.5%), penetrating injury (20.3%), inadequate foot wear (15%) and Charcot osteoartropathy (10.7%). The general amputation rate was 38.1%. Diabetic foot ulcers and its complication rates including infection, gangrene and lower extremity amputation in Turkey are still high. Preventive care of the foot in patients with diabetes mellitus is extremly important. Therefore early diagnosing of risk factors for diabetic foot infections in the primary care setting and their adequate therapy under multidisciplinary approach should not be neglected.

2020 ◽  
Vol 5 (4) ◽  
pp. 343-355
Author(s):  
Anissa Eka Septiani ◽  
◽  
Setyo Sri Rahardjo ◽  
Hanung Prasetya ◽  
◽  
...  

Author(s):  
Gusti Agung Ayu Ira Kencana Dewi ◽  
Sony Wibisono ◽  
I Putu Alit Pawana

Introduction: Diabetes mellitus is a metabolic syndrome that is marked by higher blood glucose. The uncontrolled high blood glucose can lead to complication, such as diabetic foot. Diabetic foot is the most reason why diabetic patients are hospitalized. Diabetic foot that cannot heal may lead to lower extremity amputation. The purpose of this study was to describe the risk factors of lower extremity amputation in diabetic foot ulcer patients.Methods: This study used a case-control study of diabetic foot patients in Dr. Soetomo General Hospital from January 2015 to December 2017. This study used the data from medical records in Inpatient Installation Department of Internal Medicine. Patients with diabetic foot ulcer and lower extremity amputation due to diabetes were included in this study. Incomplete medical records were excluded. Data of samples were divided to two groups, i.e. the amputation group and the non-amputation group with a ratio of 1:1. Risk factors of amputation that were analyzed were male, old age, and the history of ulcer/lower extremity amputation.Results: Based on the data of 36 samples, there were 11 male patients (61.1%) and 7 female patients (38.9%) who experienced lower extremity amputation. The average age of amputation group was 59.61 years old with a range of ages from 39 to 72 years old. This study found the risk factors for lower extremity amputation in diabetic foot ulcer patients was the history of ulcer/amputation due to diabetes (OR 5.0, 95% CI 1.065-23.464, p = 0.034). Conclusion: The risk factor for lower extremity amputation in diabetic foot ulcer patients was the history of ulcer/amputation due to diabetes. 


2012 ◽  
Vol 95 (3) ◽  
pp. 358-363 ◽  
Author(s):  
Jui-Hung Sun ◽  
Jir-Shiong Tsai ◽  
Chung-Huei Huang ◽  
Chia-Hung Lin ◽  
Hui-Mei Yang ◽  
...  

2015 ◽  
Vol 6 (1) ◽  
pp. 29629 ◽  
Author(s):  
Tjokorda Gde Dalem Pemayun ◽  
Ridho M. Naibaho ◽  
Diana Novitasari ◽  
Nurmilawati Amin ◽  
Tania Tedjo Minuljo

2019 ◽  
Vol 6 (4) ◽  
pp. 1208
Author(s):  
Girish Thimmanalli Umashankar ◽  
Anil Kumar M. S. ◽  
Mohammed Shahid

Background: Diabetic foot lesions are responsible for more hospitalisations than any other complication of diabetes and diabetes is a predominant aetiology for non-traumatic lower extremity amputations. Authors, therefore, examined the clinical characteristics that best predict poor outcome in a large population of diabetic foot ulcer patients. The objective of the study was to describe independent predictors for lower extremity amputation in patients with a diabetic foot ulcer and to validate the predictive value of PEDIS (IWGDF) classification system for a diabetic foot ulcer.Methods: A retrospective study of 197 patients presenting with diabetic foot ulcer presenting to a tertiary care hospital in Mysuru, India. The recorded parameters were age, sex, various risk factors, laboratory parameters, the presence of DM-related complications and ulcer characteristics as determined by PEDIS system. The main outcomes recorded were healed ulcer and amputation.Results: Authors have found that factors strongly associated with risk of amputation are (in order of strength): PVD, past amputation, nephropathy, past ulcer, ulcer duration, TLC, Hb and sr. creatinine. Authors also validated the PEDIS scoring system as an effective classification system with prognostic value. The PEDIS score of >7 is a highly significant predictor of adverse outcome (amputation) of diabetic foot ulcer.Conclusions: Several risk factors for lower extremity amputation in a patient with diabetic foot ulcer were identified. An integrated risk-assessment model including the above significant risk factors and PEDIS system can be developed that is both clinically accurate as well as quick to assess for predicting the adverse outcome in a patient of diabetic foot ulcer and providing an opportunity to save the limb.


2020 ◽  
Vol 4 (10) ◽  
pp. 349-352
Author(s):  
Mochamad Wildan ◽  
Sony Wibisono ◽  
Heroe Soebroto

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia. Complications are common among patients with this condition, such as diabetic foot syndrome, which is the presence of foot ulcer associated with neuropathy, PAD, and infection, and is a major cause of LEA. Aim of this research is to analyze the correlation between previous LEA as a risk factor for the subsequent LEA in patients with Diabetic Foot among patients in RSUD Dr. Soetomo, Surabaya from January-December 2018. This is descriptive cross-sectional study. Data was analyzed using descriptive statistic and correlation test with Microsoft Excel 2007 and SPSS 20. Statistical testing was performed using Spearman’s rank correlation and Cohen J criteria with significance level of P55 years old (62.9%). Mostly have undergone LEA (74.3%) while the remaining have undergone LEA twice (17.1%). There is a significant correlation between initial LEA and the subsequent LEA (p0.01). Keywords: diabetes mellitus; lower extremity amputation; risk factors; RSUD Dr. Soetomo


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