scholarly journals Bleomycin-induced Flagellate Dermatitis: a Case Report

2020 ◽  
Vol 12 (1) ◽  
pp. 15-18
Author(s):  
Beatrice Tonin ◽  
Davide Geat ◽  
Giampiero Girolomoni

AbstractFlagellate dermatitis represents a unique cutaneous eruption associated with several causes, including treatment with certain chemotherapeutic agents, ingestion of toxins and rheumatologic conditions like adult-onset Still’s disease and dermatomyositis. We present the case of a 35-year-old woman with stage IIA Hodgkin lymphoma who was treated with the ABVD chemotherapy regimen (doxorubicin, bleomycin, vinblastine and dacarbazine). During the third cycle of chemotherapy, she developed multiple linear erythematous macules and hyperpigmentation in a striking flagellate-like pattern localized on the upper chest, submammary folds, neck and upper part of the back. The lesions resolved completely within three months after the withdrawal of bleomycin. Clinicians should be aware of this distinctive cutaneous toxicity in patients receiving bleomycin combination chemotherapy.

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Camille Cotteret ◽  
Yen-Vi Pham ◽  
Ambroise Marcais ◽  
Marine Driessen ◽  
Salvatore Cisternino ◽  
...  

2019 ◽  
Vol 98 (5) ◽  
pp. E30-E31 ◽  
Author(s):  
Carla V. Valenzuela ◽  
Nancy L. Bartlett ◽  
Joseph P. Bradley

Vinca alkaloids are known to cause bilateral jaw pain that occurs once during the chemotherapy course. We report a patient with first bite syndrome (FBS) during active treatment with chemotherapy. A patient with Hodgkin lymphoma presented with unilateral jaw pain after beginning his chemotherapy regimen. Pain was worse with the first bite of each meal and dissipated over subsequent bites. Workup was negative for any lesions in the parotid, parapharyngeal space, or infratemporal fossa. Pain was timed closely with chemotherapy administration and would improve prior to next cycle. A trial of botulinum chemodenervation failed to completely relieve symptoms. The patient noted resolution of symptoms after the completion of chemotherapy. We report a case of FBS, which may represent the jaw pain seen commonly with administration of vinca alkaloids. There appears to be a correlation between onset and duration of first bite symptoms with chemotherapy administration.


2019 ◽  
Author(s):  
Collen Lauriane Le ◽  
Sara Barraud ◽  
Odou Marie Francoise ◽  
Marta Spodenkiewicz ◽  
Antoine Braconnier ◽  
...  
Keyword(s):  

2012 ◽  
Vol 74 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Naoko NAKASONE ◽  
Eriko UEHARA ◽  
Masataka KORENAGA ◽  
Sayaka YAMAGUCHI ◽  
Kenzo TAKAHASHI ◽  
...  

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