scholarly journals SURGICAL METHODS OF BLEEDING PREVENTION FROM ESOPHAGEAL VARICES IN TREATMENT FOR PATIENTS WITH LIVER CIRRHOSIS

2017 ◽  
Vol 176 (2) ◽  
pp. 13-17
Author(s):  
M. F. Zarivchatskiy ◽  
E. D. Kamenskikh ◽  
I. N. Mugatarov ◽  
M. V. Kolyvanova
Keyword(s):  
Liver Cirrhosis ◽  
Survival Rate ◽  
Esophageal Varices ◽  
Cumulative Survival ◽  
Class A ◽  
Surgical Methods ◽  
Endoscopic Ligation ◽  
Medical University ◽  
Ligation Method

E.A. Vagner Perm State Medical University OBJECTIVE. The authors would like to improve the results of surgical treatment of patients with threat of bleeding from esophageal varices. MATERIALS AND METHODS. The study included 90 patients with esophageal varices on the background of liver cirrhosis. Portocaval bypass was performed on 21 patients. The direct interventions on the stomach and esophageal varices were carried out in 29 patients. The endoscopic ligation of esophageal varices was used in 40 cases. RESULTS. The rate of cumulative survival after portocaval bypass was 93,3±6,4 % (up to1 year), 3-year survival rate counted 66,7±12,2 % and 5-year rate was 60,0±12,7 % , respectively. The rate of survival after direct interventions on the stomach and esophageal varices consisted of 92,9 %±6,9 %, 76,0±12,2 % and 65,1±14,5 %, respectively. The survival rate after the endoscopic ligation of esophageal varices class A and B in Child-Pugh numbered 100 %, 91,0±8,7 % and 54, 6±20,6 %, but in case of the class C survival rate counted 60,0±20,4 %, 45,0 %±18,8 and 22,5±18,5 %, respectively. CONCLUSIONS. The authors recommend to apply the long-term courses of endo scopic ligation of esophageal varices in order to prevent bleeding from them. The methods of portcaval bypass or direct intervention should be used in case of lack of effect of endoscopic ligation method.

scholarly journals Effect of Body Mass Index on the Prognosis of Liver Cirrhosis

2021 ◽  
Vol 8 ◽  
Author(s):  
Yue Yin ◽  
Yiling Li ◽  
Lichun Shao ◽  
Shanshan Yuan ◽  
Bang Liu ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Survival Rate ◽  
Normal Weight ◽  
Cumulative Survival Rate ◽  
Weight Group ◽  
Cumulative Survival ◽  
Normal Weight Group ◽  
Kaplan Meier ◽  
Significant Difference

Objective: At present, the association of body mass index (BMI) with the prognosis of liver cirrhosis is controversial. Our retrospective study aimed to evaluate the impact of BMI on the outcome of liver cirrhosis.Methods: In the first part, long-term death was evaluated in 436 patients with cirrhosis and without malignancy from our prospectively established single-center database. In the second part, in-hospital death was evaluated in 379 patients with cirrhosis and with acute gastrointestinal bleeding (AGIB) from our retrospective multicenter study. BMI was calculated and categorized as underweight (BMI <18.5 kg/m2), normal weight (18.5 ≤ BMI < 23.0 kg/m2), and overweight/obese (BMI ≥ 23.0 kg/m2).Results: In the first part, Kaplan–Meier curve analyses demonstrated a significantly higher cumulative survival rate in the overweight/obese group than the normal weight group (p = 0.047). Cox regression analyses demonstrated that overweight/obesity was significantly associated with decreased long-term mortality compared with the normal weight group [hazard ratio (HR) = 0.635; 95% CI: 0.405–0.998; p = 0.049] but not an independent predictor after adjusting for age, gender, and Child–Pugh score (HR = 0.758; 95%CI: 0.479–1.199; p = 0.236). In the second part, Kaplan–Meier curve analyses demonstrated no significant difference in the cumulative survival rate between the overweight/obese and the normal weight groups (p = 0.094). Cox regression analyses also demonstrated that overweight/obesity was not significantly associated with in-hospital mortality compared with normal weight group (HR = 0.349; 95%CI: 0.096-1.269; p = 0.110). In both of the two parts, the Kaplan–Meier curve analyses demonstrated no significant difference in the cumulative survival rate between underweight and normal weight groups.Conclusion: Overweight/obesity is modestly associated with long-term survival in patients with cirrhosis but not an independent prognostic predictor. There is little effect of overweight/obesity on the short-term survival of patients with cirrhosis and with AGIB.

Trapeziometacarpal total joint arthroplasty for osteoarthritis: 199 patients with a minimum of 10 years follow-up

2019 ◽  
Vol 45 (5) ◽  
pp. 443-451 ◽  
Author(s):  
Miguel Martin-Ferrero ◽  
Clarisa Simón-Pérez ◽  
Maria B. Coco-Martín ◽  
Aureliio Vega-Castrillo ◽  
Héctor Aguado-Hernández ◽  
...  
Keyword(s):  
Survival Rate ◽  
Total Joint Arthroplasty ◽  
Hand Function ◽  
Joint Arthroplasty ◽  
Implant Survival ◽  
Level Of Evidence ◽  
Term Survival ◽  
Cumulative Survival

We report outcomes of 228 consecutive patients with total joint arthroplasty using the Arpe® prosthesis, among which 216 trapeziometacarpal joints in 199 patients had a minimum of 10 years follow-up. The cumulative survival rate of the 216 implants at 10 years using the Kaplan–Meyer method was 93%. Two hundred joints were functional and painless. We found good integration and positioning of the components in 184 (93%) of the joints. Sixteen prostheses failed. We conclude that this implant has acceptable long-term survival rate and restores good hand function. We also report our methods to improve implant survival and to decrease the risk of component malpositioning, and failure rate. Level of evidence: II

Principles of primary prophylaxis of bleeding from oesophagealvaricies in patients with liver cirrhosis

2016 ◽  
Vol 94 (7) ◽  
pp. 503-509
Author(s):  
Dmitry V. Garbuzenko
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Primary Prevention ◽  
Esophageal Varices ◽  
Retrieval System ◽  
Primary Prophylaxis ◽  
Inclusion Criteria ◽  
Cochrane Reviews ◽  
Pubmed Database ◽  
Endoscopic Ligation

The principles of primary prevention of bleeding from esophageal varices in patients with liver cirrhosis are discussed with reference to the stage ofportal hypertension. The information was collectedfrom the PubMed database, Google Scholar retrieval system, Cochrane reviews, and lists of references from relevant publications for 1980-2015 using the key words «bleeding from esophageal varices», «prophylaxis», «portal hypertension». Inclusion criteria were confined to primary prophylaxis of bleeding from esophageal varices in patients with liver cirrhosis. The analysis showed that the drugs of choice for primary prophylaxis of bleeding from esophageal varices in patients with liver cirrhosis are non-selective beta-adrenoblockers, but their application is indicated only in case of clinicallyl significant portal hypertension in patients with large and mediumsize esophageal varices. When the use of these drugs is contraindicated, endoscopic ligation of esophageal varices can be recommended.

Impact on Survival of the Extent of Resection in Unrelapsed Lung Cancer

1983 ◽  
Vol 69 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Amedeo Vittorio Bedini ◽  
Ugo Pastorino ◽  
Maurizio Valente ◽  
Gianni Ravasi
Keyword(s):  
Lung Cancer ◽  
Survival Rate ◽  
Extent Of Resection ◽  
Cumulative Survival ◽  
Impact On Survival ◽  
Young Subjects ◽  
Resected Stage ◽  
The Impact ◽  
Long Term Mortality

Five-year survival of resected stage la non-oat cell lung cancer was evaluated in 69 consecutive patients without recurrence. The impact of the extent of resection on perioperative and long-term mortality was studied after an evaluation of confounding factors, such as age and associated cardiopulmonary diseases, which further stratified our series. Our patients were subdivided into 2 groups: the first included lobectomies and was further subdivided into 2 subsets according to whether the operation had caused the resection of less than 4 (30 cases) or more than 3 segments (18 cases). The second one included pneumonectomies (21 cases). Thirty-two patients were 60 years or older; pulmonary and/or cardiovascular diseases were assessed in 38 patients. There were 6 perioperative deaths, 3 among major lobectomies (more than 3 segments resected) and 3 among pneumonectomies. Survival rate of lobectomies was 75% (86% for minor, 55% for major lobectomies), and 57% for pneumonectomies. Major lobectomies included the highest percentage of elderly patients with cardiopulmonary diseases who had significantly poorer survival probabilities than young subjects without cardiopneumopathies. Lobectomy cases, after standardization by age, had a significantly higher probability of surviving than pneumonectomy cases. Standardization by cardiopulmonary disease showed a better chance for lobectomy cases, although it was not significant. Major lobectomy cases had poorer cumulative survival rate than minor lobectomy cases. Such a difference was revealed in patients 60 years or older and in those with pneumocardiopathies.

scholarly journals EVALUATION OF THE QUALITY OF LIFE OF PATIENTS WITH CIR-RHOSIS AFTER SURGICAL PREVENTION OF BLEEDING FROM VARI-COSEVEINS OF THE ESOPHAGUS

2020 ◽  
pp. 185-189
Keyword(s):  
Liver Cirrhosis ◽  
Varicose Veins ◽  
Scientific Work ◽  
Gastric Bleeding ◽  
Class B ◽  
Endoscopic Ligation ◽  
B 31

The scientific work is based on the experience of endoscopic ligation of varicose veins of the esophagus (EVV) in 65 patients with liver cirrhosis with portal hypertension syndrome. The degree of ERVP was established in accordance with the classification of K.J. Paquet (1982). Varicose veins of the esophagus of III and IV degrees were recorded in 58 (89.2%) patients. For a comprehensive assessment of the degree of liver failure, the Child-Pugh scale was used (1973). 11 (16.9%) patients were assigned to class A, 23 (35.4%) to class B, 31 (47.7%) patients to class C. The effectiveness of endoscopic ligation in the prevention of bleeding was 92.2%. Recurrence of esophageal-gastric bleeding in the immediate period occurred in 3 patients. Hospital mortality was 4.6%. In the long-term period after endoscopic eradication, recurrence of esophageal varicose veins was diagnosed in 27.8% of patients. Endoscopic ligation of varicose veins of the esophagus is an effective method for stopping and preventing bleeding in patients with liver cirrhosis.

Long-term prognosis in children with benign cerebellar astrocytoma

1978 ◽  
Vol 49 (2) ◽  
pp. 179-184 ◽  
Author(s):  
Flemming Gjerris ◽  
Leif Klinken
Keyword(s):  
Survival Rate ◽  
Morphological Difference ◽  
Diffuse Type ◽  
Single Patient ◽  
Content Type ◽  
Cumulative Survival ◽  
Cerebellar Astrocytoma ◽  
Juvenile Type ◽  
Long Term Prognosis

✓ In 44 children with benign cerebellar astrocytoma, operated on between 1935 and 1959, two histological types could be distinguished, namely, a so-called juvenile type (31 children) and a diffuse type (13 children). All the children were followed to April, 1976, and the histological review was performed without knowledge of the survival in the single patient. For children with the juvenile type of cerebellar astrocytoma the 25-year cumulative survival rate was 94%, as against 38% for children with the diffuse type. It has thus been demonstrated that the morphological difference between the two types corresponds to a marked difference in survival rate.

scholarly journals Prevention of recurrent bleeding from varicose veins of the esophagus and stomach among patients with decompensated liver cirrhosis

2019 ◽  
Vol 100 (2) ◽  
pp. 333-339
Author(s):  
I E Onnitsev ◽  
S A Bugaev ◽  
S Ya Ivanusa ◽  
I I Dzidzava ◽  
A V Khokhlov ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Esophageal Varices ◽  
Varicose Veins ◽  
Treatment Method ◽  
Recurrent Bleeding ◽  
Gastric Bleeding ◽  
Decompensated Liver Cirrhosis ◽  
Risk Of Bleeding ◽  
Results Of Treatment ◽  
Endoscopic Ligation

Aim. To evaluate the efficiency of laparoscopic devascularization of the esophagus and stomach with endoscopic ligation of varicose esophageal veins in the prevention of esophageal-gastric bleeding among patients with decompensated liver cirrhosis. Methods. The results of treatment of 73 patients with decompensated liver cirrhosis and high risk of bleeding were analyzed. To prevent recurrent bleeding from esophageal and gastric veins, all patients underwent endoscopic ligation at the first step of treatment. In case of inefficiency of ligation and recurrence of varicose veins of esophagus, laparoscopic devascularization of esophagus and stomach was performed. The efficiency of laparoscopic devascularization with intraoperative endoscopic ligation of varicose esophageal veins and ligation as an independent method of treatment for the prevention of upper gastrointestinal bleeding was estimated by comparison of the frequency of recurrence of esophageal and gastric bleeding and recurrence of esophageal varices according to upper endoscopy in comparison groups. Results. In 6 months, 1 and 2 years after laparoscopic devascularization of the esophagus and stomach in combination with endoscopic ligation, the risk of bleeding is less compared to endoscopic ligation as an isolated treatment method (p=0.05; p=0.052; p=0.06). Laparoscopic devascularization with ligation reduces the risk of recurrence of esophageal varices during the first year after surgery by 20% (χ2=2.61; p=0.106), in 2 years by 23% (χ2=1.75; p=0.091) compared to endoscopic ligation only. Conclusion. Patients with liver cirrhosis with decompensated hepatic failure satisfactorily postpone endovideosurgical interventions; laparoscopic gastric devascularization with the intersection of the main inflows to the esophageal varicose veins is an effective method to prevent esophageal-gastric hemorrhage among patients with decompensated liver cirrhosis after ineffective endoscopic ligation.

scholarly journals Long-term Retrospective Study on Cumulative Survival Rate of Implants with Guided Bone Regeneration

2018 ◽  
Vol 22 (4) ◽  
pp. 196-209
Author(s):  
Suk-Hyun Jung ◽  
Jun-Hwan Kim ◽  
Da-Jeong Namgung ◽  
Yun-Jeong Kim ◽  
Jaeeun Chung ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Survival Rate ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Cumulative Survival Rate ◽  
Cumulative Survival
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