Association between Vitamin D deficiency and Asthma control test in adults: A cross-sectional study in a college hospital in Jeddah, Saudi Arabia

Abstract Background : Asthma is the most common chronic diseases that affect children and its prevalence is increasing worldwide posing a great burden on healthcare systems. A growing body of evidence suggests an association between vitamin D deficiency and asthma. The current study aimed to assess serum vitamin D level in Jordanian children with bronchial asthma and to examine the correlation between vitamin D levels and asthma severity and control. Methods: A cross sectional study was conducted in the Pediatric Chest Clinic at AlKarak Governmental Hospital South of Jordan from May 2015 to February 2016. Serum level of 25-hydroxyvitamin-D was determined for 98 Children aged 1 to 14 years and diagnosed with bronchial asthma (6-14years) or recurrent wheezing episodes(<6 years). The severity of asthma was determined based on the Global Initiative for Asthma (GINA) assessment, the Asthma Control test (ACT) and the Childhood Asthma Control Test (C-ACT). The results were considered significant if P ≤.05. Statistical analysis was performed using SPSS 21 (IBM, Armonk, NY, United States of America, 2012). Results : Vitamin D levels were deficient and insufficient in 41(41.8%) and 34(34.7%) of asthmatic children, respectively. Only 23( 23.5%) had sufficient vitamin D levels. A significant correlation was found between the severity of asthma symptoms and vitamin D deficiency (Pearson Chi-squared=.028). Conclusion : Vitamin D deficiency is highly prevalent in children with bronchial asthma in Jordanian population and correlates significantly with asthma severity. Assessment of vitamin D levels in children with bronchial asthma is required in a larger scale studies in Jordan.

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Awareness of vitamin D deficiency among the adult population in Makkah, Saudi Arabia: a cross-sectional study

International Journal of Medicine in Developing Countries ◽

10.24911/ijmdc.51-1600516858 ◽

2020 ◽

pp. 1818-1822

Author(s):

Reda Goweda ◽

Saud Zakaria ◽

Hisham Foudah ◽

Alwaleed Almalki ◽

Majed Alsulami ◽

...

Keyword(s):

Vitamin D ◽

Saudi Arabia ◽

Vitamin D Deficiency ◽

Adult Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Vitamin D deficiency in children with bronchial asthma in southern Jordan: a cross-sectional study

Journal of International Medical Research ◽

10.1177/0300060520974242 ◽

2020 ◽

Vol 48 (12) ◽

pp. 030006052097424

Author(s):

Enas Al-Zayadneh ◽

Nedal Awad Alnawaiseh ◽

Salma Ajarmeh ◽

Areej Hamed Altarawneh ◽

Eman M Albataineh ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Bronchial Asthma ◽

Asthma Severity ◽

Cross Sectional Study ◽

Sectional Study ◽

Asthma Control Test ◽

Cross Sectional ◽

Vitamin D Levels ◽

25 Oh Vitamin D

Objectives To assess serum 25-hydroxycholecalciferol (25-OH vitamin D) levels in Jordanian children with bronchial asthma, and to examine correlations between 25-OH vitamin D levels and asthma severity and control. Methods A cross-sectional study was conducted at the Paediatric Chest Clinic, Al-Karak Governmental Hospital, Southern Jordan, between May 2015 and February 2016. Serum 25-hydroxyvitamin D level was determined in children aged 1–14 years diagnosed with bronchial asthma (6–14 years) or recurrent wheezing episodes (<6 years). Asthma severity was determined based on the Global Initiative for Asthma assessment, the Asthma Control Test, and the Childhood Asthma Control Test. Demographic and clinical characteristics were compared between patients with low and normal 25-OH vitamin D levels, and correlations between asthma severity and 25-OH vitamin D level were assessed. Results Out of 98 included children, 25-OH vitamin D levels were deficient and insufficient in 41 (41.8%) and 34 (34.7%) children, respectively. Only 23 (23.5%) had sufficient 25-OH vitamin D levels. A significant correlation was found between severity of asthma symptoms and 25-OH vitamin D deficiency. Conclusion 25-OH vitamin D deficiency is highly prevalent in Jordanian children with bronchial asthma and correlates significantly with asthma severity.

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