Cross-sectional study assessing the performance of the Arabic translated childhood asthma control test

Background: Children from low- and middle-income countries have poor asthma control, mainly because of poor management. The extent of this problem in Uganda is not well known, but such information would be useful to guide policy and practice. We therefore conducted a cross-sectional study among schoolchildren with asthma in urban Uganda, to assess the level of asthma control and management. Methods: Schoolchildren aged 5-17 years were enrolled, asthma was diagnosed by the study medical team. Asthma control was assessed using the Asthma Control Test and the childhood Asthma Control Test. Data on previous asthma management was obtained using interviewer-led questionnaires. Data were analysed using multiple linear and multiple logistic regression. Results: We enrolled 561 children with asthma, of whom only 56% had ever had an asthma diagnosis. We categorised asthma as well-controlled (55.5%), partly-controlled (29.5%) and poorly-controlled (15.0%). Poor asthma control was associated with increasing age (adjusted regression coefficient [95% confidence interval], p-value: -1.07 [-1.20, -0.94], p<0.0001), concurrent allergic rhinitis (-1.33 [-2.28, -0.38], p=0.006), and city residence in early life (-1.99 [-3.69, -0.29], p=0.06). Regular use of inhaled asthma medication in the last 12 months was very low; 18.1% for salbutamol and 6.7% for inhaled corticosteroids. The main barriers to inhaled asthma medication use were lack of prescription (47.6%) and inaccurate diagnosis (38.8%). Increased inhaler use was associated with tertiary education of the fathers (adjusted odds ratio [95% confidence interval], p-value: 5.19 [2.39-11.28], p<0.0001), city residence in early life (4.66 [1.79-12.43], 0.002) and an asthma diagnosis prior to enrolment (11.39 [6.35-20.43], p<0.0001). Conclusions: This study confirms that children with asthma in Uganda generally have inadequate asthma control, which is attributable to poor asthma management. This could be improved through re-training of medical workers and patient education, and by increasing availability and affordability of essential asthma medications.

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Development and cross-sectional validation of the Childhood Asthma Control Test

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2006.12.662 ◽

2007 ◽

Vol 119 (4) ◽

pp. 817-825 ◽

Cited By ~ 474

Author(s):

Andrew H. Liu ◽

Robert Zeiger ◽

Christine Sorkness ◽

Todd Mahr ◽

Nancy Ostrom ◽

...

Keyword(s):

Asthma Control ◽

Childhood Asthma ◽

Control Test ◽

Asthma Control Test ◽

Cross Sectional

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Vitamin D deficiency in Jordanian children with bronchial asthma : a cross sectional study

10.21203/rs.3.rs-34670/v1 ◽

2020 ◽

Author(s):

Enas Al-Zayadneh ◽

Nedal Awad Alnawaiseh ◽

Salma Ajarmeh ◽

Areej Hamed Altarawneh ◽

Eman M. Albataineh ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Bronchial Asthma ◽

Asthma Severity ◽

Cross Sectional Study ◽

Control Test ◽

Sectional Study ◽

Asthma Control Test ◽

Cross Sectional ◽

Vitamin D Levels

Abstract Background : Asthma is the most common chronic diseases that affect children and its prevalence is increasing worldwide posing a great burden on healthcare systems. A growing body of evidence suggests an association between vitamin D deficiency and asthma. The current study aimed to assess serum vitamin D level in Jordanian children with bronchial asthma and to examine the correlation between vitamin D levels and asthma severity and control. Methods: A cross sectional study was conducted in the Pediatric Chest Clinic at AlKarak Governmental Hospital South of Jordan from May 2015 to February 2016. Serum level of 25-hydroxyvitamin-D was determined for 98 Children aged 1 to 14 years and diagnosed with bronchial asthma (6-14years) or recurrent wheezing episodes(<6 years). The severity of asthma was determined based on the Global Initiative for Asthma (GINA) assessment, the Asthma Control test (ACT) and the Childhood Asthma Control Test (C-ACT). The results were considered significant if P ≤.05. Statistical analysis was performed using SPSS 21 (IBM, Armonk, NY, United States of America, 2012). Results : Vitamin D levels were deficient and insufficient in 41(41.8%) and 34(34.7%) of asthmatic children, respectively. Only 23( 23.5%) had sufficient vitamin D levels. A significant correlation was found between the severity of asthma symptoms and vitamin D deficiency (Pearson Chi-squared=.028). Conclusion : Vitamin D deficiency is highly prevalent in children with bronchial asthma in Jordanian population and correlates significantly with asthma severity. Assessment of vitamin D levels in children with bronchial asthma is required in a larger scale studies in Jordan.

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Asthma Control in Hospital Tengku Ampuan Afzan, Kuantan, Malaysia: A Cross-sectional Study

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v14i2.433 ◽

2020 ◽

Vol 14 (2) ◽

Author(s):

Kuan YC ◽

Tan CH ◽

Hong CM ◽

How SH

Keyword(s):

Asthma Control ◽

Bronchial Asthma ◽

Tertiary Hospital ◽

Cross Sectional Study ◽

Fixed Dose ◽

Sectional Study ◽

Act Scores ◽

Asthma Control Test ◽

Cross Sectional ◽

Chest Clinic

Introduction: Various initiatives and medications have been introduced to achieve better control of bronchial asthma. However total control according to Global Initiative for Asthma (GINA) remains elusive even at tertiary referral hospitals. Our study is to determine the level of asthma control (according to GINA 2009), Asthma Control Test (ACT) scores and the types of medications used among patients with bronchial asthma in a large tertiary hospital. Methods: A cross-sectional study of all patients with bronchial asthma who attended the Chest Clinic at Hospital Tengku Ampuan Afzan (HTAA) from 2009 to 2011. Patient demographics, self-administered ACT scores, GINA-defined level of asthma control and medications were documented. Results: 208 patients were recruited. There were 23.2%, 46.3% and 30.5% of patients with controlled, partly controlled and uncontrolled asthma respectively. The median ACT scores was 19 [inter quartile range (IQR) 6]. The most frequently used preventer therapy was inhaled long-acting β-agonist/corticosteroids (LABA/ICS) fixed-dose combination (61.7%), and 9.6% were not on preventer therapy. 75% of patients with controlled asthma were on LABA/ICS compared to 58.5% of the partly controlled and uncontrolled groups (p=0.039). Conclusion: The majority of the asthmatic patients attending the Chest Clinic at HTAA did not have GINA-defined controlled asthma. Patients with higher ACT scores had better control of asthma. There were more patients with controlled asthma who were on LABA/ ICS combination.

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Association between Allergic Rhinitis and Asthma Control in Peruvian School Children: A Cross-Sectional Study

BioMed Research International ◽

10.1155/2013/861213 ◽

2013 ◽

Vol 2013 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Justo Padilla ◽

Mónica Uceda ◽

Otto Ziegler ◽

Felipe Lindo ◽

Eder Herrera-Pérez ◽

...

Keyword(s):

Allergic Rhinitis ◽

Asthma Control ◽

School Children ◽

Score Test ◽

Positive Association ◽

Cross Sectional Study ◽

Sectional Study ◽

Asthma Control Test ◽

Cross Sectional ◽

Prevalence Ratios

Background. Asthma and allergic rhinitis are highly prevalent conditions that cause major illness worldwide. This study aimed to assess the association between allergic rhinitis and asthma control in Peruvian school children.Methods. A cross-sectional study was conducted among 256 children with asthma recruited in 5 schools from Lima and Callao cities. The outcome was asthma control assessed by the asthma control test. A score test for trend of odds was used to evaluate the association between allergic rhinitis severity and the prevalence of inadequate asthma control. A generalized linear regression model was used to estimate the adjusted prevalence ratios of inadequate asthma control.Results. Allergic rhinitis was present in 66.4% of the population with asthma. The trend analysis showed a positive association between allergic rhinitis and the probability of inadequate asthma control (). It was associated with an increased prevalence of inadequate asthma control, with adjusted prevalence ratios of 1.53 (95% confidence interval: 1.19−1.98).Conclusion. This study indicates that allergic rhinitis is associated with an inadequate level of asthma control, giving support to the recommendation of evaluating rhinitis to improve asthma control in children.

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A cross sectional study of patients with poorly controlled asthma at a referral centre

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20191147 ◽

2019 ◽

Vol 6 (2) ◽

pp. 393

Author(s):

Shobitha Rao

Keyword(s):

Asthma Control ◽

Cross Sectional Study ◽

Control Measures ◽

Sectional Study ◽

Asthma Control Test ◽

Cross Sectional ◽

Common Chronic Disease ◽

Dust Mite ◽

Detailed Evaluation ◽

Indoor And Outdoor

Background: Asthma is a common chronic disease of the airways. Poorly controlled asthma has significant impact on social and economic factors. This study was done to analyse the clinical profile of patients with poorly controlled asthma.Methods: This is an observational, cross sectional study. Total of 100 patients were evaluated. Data collected included symptomatology, assessment of asthma control by asthma control test scoring, spirometry, body mass index, co-morbidities and allergy testing report.Results: Among the 100 patients studied, 52% (n=52) were in the age group of 30 to 60 years. 48% (n=48) were males and 52% (n=52) were females. 76% (n=76) patients had adhered to treatment for bronchial asthma as advised which was in line with standard therapy. 86% (n=86) had co-existing illness. They included allergic rhinitis, obesity, GERD, anxiety, atopic dermatitis and chronic urticaria. 78% (n=78) of these cases were sensitized to indoor and outdoor allergens. 89% of sensitized cases were to house dust mite (n=70 of 78). This was followed by cockroach sensitization which was seen in 30.7% cases (n=24 of 78). Other allergens included pollens in 28.2% cases (n=22 of 78), aspergillus in 25.6% cases (n=20 of 78) and food allergens in 23% cases (n=18 of 78).Conclusions: Poorly controlled asthma cases require detailed evaluation of comorbid conditions and allergen sensitization profiles. Management of these conditions along with allergen control measures may benefit these patients along with step up of therapy.

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The potential role of local pharmacies to assess asthma control: an Italian cross-sectional study

BMC Public Health ◽

10.1186/s12889-020-10080-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

M. Caminati ◽

L. Cegolon ◽

M. Bacchini ◽

N. Segala ◽

A. Dama ◽

...

Keyword(s):

Asthma Control ◽

Multinomial Logistic Regression ◽

Asthma Severity ◽

Cross Sectional Study ◽

Disease Assessment ◽

Community Pharmacies ◽

Sectional Study ◽

Cross Sectional ◽

Care Services ◽

Disease Community

Abstract Background Asthma control and monitoring still represents a challenge worldwide. Although the international guidelines suggest the interplay between secondary and primary care services as an effective strategy to control the disease, community pharmacies’ are seldom involved in asthma control assessment. The present cross-sectional study aimed at providing a picture of the relationship between asthma severity and control in community pharmacies within the health district of the city of Verona (Veneto Region, North-Eastern Italy). Methods A call for participation was launched through the Pharmacists’ Association of Verona. Patients referring to the participating pharmacies with an anti-asthmatic drug medical prescription and an asthma exemption code were asked to complete the Asthma Control Test (ACT) and a brief questionnaire collecting information on their age, sex, smoking status, aerobic physical exercise and usual asthma therapy, which also defined asthma severity. A multinomial logistic regression model was fitted to investigate the risk of uncontrolled as well as poorly controlled vs. controlled asthma (base). Results were expressed as relative risk ratios (RRR) with 95% confidence interval (95%CI). Results Fifty-seven community pharmacies accepted to participate and 584 asthmatic patients (54% females; mean-age: 51 ± 19 years) were consecutively recruited from 1st January to 30th June 2018 (6 months). Based upon ACT score 50.5% patients had a controlled asthma, 22.3% a poorly controlled and 27.2% uncontrolled. A variable proportion of patients with uncontrolled asthma were observed for every level of severity, although more frequently with mild persistent form of asthma. Most patients (92%) self-reported regular compliance with therapy. At multinomial regression analysis, patients under regular asthma treatment course (RRR = 0.33; 95%CI: 0.15; 0.77) were less likely to have an ACT< 16 compared to those not taking medications regularly. Conclusions Overall, our findings highlighted an unsatisfactory asthma control in the general population, independently of the severity level of the disease. Community pharmacies could be a useful frontline interface between patients and the health care services, supporting an effective asthma management plan, from disease assessment and monitoring treatment compliance to referral of patients to specialist medical consultancies.

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