scholarly journals Infantile systemic lupus erythematous presenting as nephrotic syndrome in a 12-month-old boy: a case report

2021 ◽  
Vol 63 (2) ◽  
pp. 339
Author(s):  
Ece Mekik Akar ◽  
Zeynep Birsin Özçakar ◽  
Nilgün Çakar ◽  
Saba Kiremitçi ◽  
Eda Didem Kurt Şükür ◽  
...  
2020 ◽  
Vol 12 (6) ◽  
pp. 127-128
Author(s):  
Susana Rodrigues ◽  
Catrine Ferreira ◽  
Tiago Coelho ◽  
Diogo Gaspar ◽  
Jean Fallah ◽  
...  

Calcinosis cutis is a rare disorder characterized by of deposition of insoluble calcium salts in the skin and subcutaneous tissue. Five subtypes of calcinosis cutis are described: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis.1 Of these subtypes, dystrophic calcinosis (DC) is the most common, and it is the most frequently seen in association with underlying autoimmune connective tissue diseases.2 Dermatomyositis, systemic sclerosis and less commonly systemic lupus erythematous were described to be complicated by DC. However, DC associated with rheumatoid arthritis (RA) is extremely rare.2 The condition causes substantial morbidity and is associated with pain and limitation of movement when the process involves areas close to joints or when ulceration occurs.2 We report a middle age Sudanese woman with good controlled RA who developed dystrophic calcinosis cutis.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 552
Author(s):  
Horacio Suárez-Ale ◽  
Elizabeth Fabian-Aquino ◽  
Virgilio E Failoc-Rojas ◽  
Vicente A Benites-Zapata ◽  
Felipe Ignacio-Cconchoy

Thrombotic thrombocytopenic purpura (TTP) is an uncommon microangiopathic disease and often occurs as a complication of systemic lupus erythematous (SLE). However, this probable causal relationship has not been completely proven. The diagnostic differentiation of both diseases is difficult in the first instance because they share similar characteristics that may overlap. We present a case of a 32-year-old woman with antecedents of epilepsy since she was 12 years old. The patient was admitted to the emergency room with a clinical picture of headaches, fever, paleness in the skin and mucosa, confused state, paresthesia, and transient spasticity of the extremities. The laboratory results revealed Coombs negative direct autoimmune hemolytic anaemia, severe thrombocytopenia, significant elevation of the enzyme lactate dehydrogenase, and presence of schistocytes ++ in the peripheral film.  In addition, positive antinuclear antibodies and positive anti-native DNA in titers of 1/320 and 1/160, respectively, were found. Renal function was conserved. We concluded that it was a case of TTP associated with SLE and indicated treatment with plasmapheresis and methylprednisolone pulses, obtaining a satisfactory response (normalization of biomarker levels, health condition) after the second session of plasmapheresis. Diagnosis of both SLE and TTP is often difficult to achieve; however, adequate correlation of clinical manifestations and laboratory tests, along with the help of partial therapeutic interventions, may lead to good clinical response.


2018 ◽  
Vol 20 ◽  
pp. e00083
Author(s):  
Charalampos Karachalios ◽  
Panagiotis Bakas ◽  
Anastasia Beta ◽  
Efthimios Deligeoroglou

Author(s):  
CATARINA RODRIGUES ROSA DE OLIVEIRA ◽  
CAMILA MARIA BEDERRIBEIRO GIRISH PANJWANI ◽  
CLAYTON CLENISSON DE CARVALHO SILVA ◽  
VANESSA DE CARLA BATISTA DOS SANTOS ◽  
EULINA MARIA VIEIRA DE ABREU ◽  
...  

Author(s):  
Salwa Dafa Allah Salih Mohammadeen ◽  
Amar F.Eldow ◽  
Rania Eisa Abdelmutalib ◽  
Sara galal osman hamza ◽  
Elnour Mohammed Elagib ◽  
...  

A middle-aged Sudanese woman has been presented complained about multiple joint pain, skin rash, chest pain, hair loss, severe abdominal pain associated with abdominal distension, bloody diarrhoea and vomiting. Lab investigation and computed tomography (CT) abdomen revealed the patient have an intussusception on top of SLE. The patient was treated


2017 ◽  
Vol 5 (1) ◽  
pp. 75
Author(s):  
Isabel Carolina Veríssimo Vendramini ◽  
Danielle Pereira Barros ◽  
Úrsula Soares Barbosa ◽  
Vanessa De Oliveira Magalhães ◽  
Nilzio Antônio da Silva ◽  
...  

ResumoObjetivo: Apresentar um caso de síndrome nefrótica, secundária a sífilis, mimetizando Lupus Eritematoso Sistemico. Relato do caso: Mulher jovem, de 26 anos, evoluiu com úlceras orais dolorosas, artralgia e síndrome nefrótica, sendo aventada, inicialmente, a possibilidade de doença autoimune. Os resultados dos exames laboratoriais afastaram a possibilidade de lupus eritematoso sistêmico e confirmaram o diagnóstico de sífilis. Considerações finais: A presença de síndrome nefrótica, em paciente jovem do gênero feminino, deve suscitar a investigação da história sexual pregressa, sendo a sífilis uma possibilidade obrigatória nesta investigação, a qual pode mimetizar o LES, retardando o diagnóstico precoce e o tratamento eficaz.Palavras-chave:Lupus eritematoso sistêmico. Síndrome nefrótica. SífilisAbstractObjective: To present a case of nephrotic syndrome, secondary to syphilis, mimicking systemic lupus erythematosus. Case report: 26-year-old woman who developed painful oral ulcers, arthralgia and nephrotic syndrome, and the possibility of autoimmune disease was initially suggested. The results of the laboratory tests removed the possibility of systemic lupus erythematosus and confirmed the diagnosis of syphilis. Final considerations: The presence of nephrotic syndrome in a young female patient should trigger the investigation of previous sexual history, and syphilis is a mandatory possibility in this investigation, which can mimic SLE, delaying early diagnosis and effective treatment.Keyword:Systemic lupus erythematosus. Nephrotic syndrome. Syphilis.


2017 ◽  
Vol 18 ◽  
pp. 1396-1400 ◽  
Author(s):  
Darío A. Rueda ◽  
Luisina Aballay ◽  
Lisandro Orbea ◽  
Diego A. Carrozza ◽  
Paola Finocchietto ◽  
...  

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