Role of prostaglandin D(2) in equine allergic diseases

2016 ◽  
Vol 4 (Suppl. 3) ◽  
pp. A2.6
Author(s):  
Georg M. Racic
Keyword(s):  
2012 ◽  
Vol 46 (6) ◽  
pp. 379-383 ◽  
Author(s):  
N. L. Kutsenko ◽  
O. V. Izmailova ◽  
L. E. Vesnina ◽  
I. P. Kaidashev

2014 ◽  
Vol 124 (3) ◽  
pp. 301-306 ◽  
Author(s):  
Ryosuke Segawa ◽  
Noriyasu Hirasawa
Keyword(s):  

Author(s):  
Drew Provan

This chapter covers the role of the immunology laboratory in the diagnosis of immunological and allergic disorders, including testing for autoimmune diseases, allergic diseases, lymphocyte and neutrophil phenotype and function, and immunochemical analysis of serum proteins for the diagnosis of immune deficiency and myeloma. Information is provided on the tests, with ranges and explanation of the interpretation of abnormal results. Critical results requiring immediate action are highlighted.


Antibodies ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 69
Author(s):  
Yasmine Lamri ◽  
Nicolas Charles

Systemic lupus erythematosus (SLE) is a multifactorial chronic autoimmune disease, marked by the presence of autoantibodies to nuclear antigens belonging to different isotype classes. For several years, IgE antibodies have been incriminated in the development of allergic diseases and parasitic infections and different anti-IgE therapies have been developed to encounter the pathogenic role of IgE in these pathologies. Recently, multiple studies showed the presence of elevated total IgE levels and demonstrated a pathogenic role of autoreactive IgE in SLE. This review aims to summarize the findings incriminating IgE and autoreactive IgE in the pathophysiology of SLE, to describe their functional outcomes on their targeted cells as well as to discuss different IgE-related therapeutic modalities that emerged and that may be beneficial for SLE patient care.


1994 ◽  
Vol 2 (4) ◽  
pp. 240-247 ◽  
Author(s):  
Hans-Jørgen Malling
Keyword(s):  

2019 ◽  
Vol 40 (3) ◽  
pp. 138-145 ◽  
Author(s):  
M. Asghar Pasha ◽  
Gargi Patel ◽  
Russell Hopp ◽  
Qi Yang

Background: Over the past decade, there has been increasing interest and research into understanding the type 2 immune responses by the epithelium-derived cytokines interleukin (IL) 33, IL-25, and thymic stromal lymphopoietin. Innate lymphoid cells (ILC) are a unique family of effector immune cells that functionally resemble T cells but lack clonal distributed antigen receptors. Group 2 ILCs, ILC2s, are known for their capability to secrete proallergic cytokines, including IL-5 and IL-13. ILC2s are enriched at mucosal barriers in lung, gut, and skin, and their activation has been associated with a variety of allergic disorders. Objective: To study the role of ILC2 in different allergic disorders, including allergic rhinitis, asthma, atopic dermatitis, and food allergies. Methods: A MEDLINE search was performed for articles that reported on ILC2 in allergic disorders, including allergic rhinitis, asthma, atopic dermatitis, and food allergies. Results: A review of the literature revealed an important role of ILC2 in various allergic disorders. Conclusion: Identification of ILC2s in patients with allergic rhinitis, asthma, and atopic dermatitis indicates that these cells may represent a new therapeutic target. In this review, we discussed the current understanding of ILC2 biology and its function and regulation in various allergic diseases.


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