Numerical Investigation of Three-Dimensional Ice Formation on a Wing with Leading Edge Tubercles

2022 ◽  
Author(s):  
Lorenzo Beretta ◽  
Myles C. Morelli ◽  
Alberto Guardone ◽  
Giuseppe Quaranta
Author(s):  
Bo Wang ◽  
Yanhui Wu ◽  
Kai Liu

Driven by the need to control flow separations in highly loaded compressors, a numerical investigation is carried out to study the control effect of wavy blades in a linear compressor cascade. Two types of wavy blades are studied with wavy blade-A having a sinusoidal leading edge, while wavy blade-B having pitchwise sinusoidal variation in the stacking line. The influence of wavy blades on the cascade performance is evaluated at incidences from −1° to +9°. For the wavy blade-A with suitable waviness parameters, the cascade diffusion capacity is enhanced accompanied by the loss reduction under high incidence conditions where 2D separation is the dominant flow structure on the suction surface of the unmodified blade. For well-designed wavy blade-B, the improvement of cascade performance is achieved under low incidence conditions where 3D corner separation is the dominant flow structure on the suction surface of the baseline blade. The influence of waviness parameters on the control effect is also discussed by comparing the performance of cascades with different wavy blade configurations. Detailed analysis of the predicted flow field shows that both the wavy blade-A and wavy blade-B have capacity to control flow separation in the cascade but their control mechanism are different. For wavy blade-A, the wavy leading edge results in the formation of counter-rotating streamwise vortices downstream of trough. These streamwise vortices can not only enhance momentum exchange between the outer flow and blade boundary layer, but also act as the suction surface fence to hamper the upwash of low momentum fluid driven by cross flow. For wavy blade-B, the wavy surface on the blade leads to a reduction of the cross flow upwash by influencing the spanwise distribution of the suction surface static pressure and guiding the upwash flow.


2021 ◽  
Vol 22 (7) ◽  
pp. 3618
Author(s):  
Emmanuel N. Paul ◽  
Gregory W. Burns ◽  
Tyler J. Carpenter ◽  
Joshua A. Grey ◽  
Asgerally T. Fazleabas ◽  
...  

Uterine fibroid tissues are often compared to their matched myometrium in an effort to understand their pathophysiology, but it is not clear whether the myometria of uterine fibroid patients represent truly non-disease control tissues. We analyzed the transcriptomes of myometrial samples from non-fibroid patients (M) and compared them with fibroid (F) and matched myometrial (MF) samples to determine whether there is a phenotypic difference between fibroid and non-fibroid myometria. Multidimensional scaling plots revealed that M samples clustered separately from both MF and F samples. A total of 1169 differentially expressed genes (DEGs) (false discovery rate < 0.05) were observed in the MF comparison with M. Overrepresented Gene Ontology terms showed a high concordance of upregulated gene sets in MF compared to M, particularly extracellular matrix and structure organization. Gene set enrichment analyses showed that the leading-edge genes from the TGFβ signaling and inflammatory response gene sets were significantly enriched in MF. Overall comparison of the three tissues by three-dimensional principal component analyses showed that M, MF, and F samples clustered separately from each other and that a total of 732 DEGs from F vs. M were not found in the F vs. MF, which are likely understudied in the pathogenesis of uterine fibroids and could be key genes for future investigation. These results suggest that the transcriptome of fibroid-associated myometrium is different from that of non-diseased myometrium and that fibroid studies should consider using both matched myometrium and non-diseased myometrium as controls.


Ground Water ◽  
2019 ◽  
Vol 58 (2) ◽  
pp. 278-290 ◽  
Author(s):  
Yun Zhang ◽  
Xuexin Yan ◽  
Tianliang Yang ◽  
Jichun Wu ◽  
Jianzhong Wu

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