Eco-Friendly Synthesis of Pyrazoline Derivatives

Pyrazoline class of compounds serve as better moieties for an array of treatments, they have antibacterial, antifungal, antiinflammatory, antipyretic, diuretic, cardiovascular activities. Apart from these they also have anticancer activities. So, pertaining to its importance, many attempts are made to synthesize pyrazolines. Since conventional methods of organic synthesis are energy and time consuming. There are elaborate pathways for green and eco-friendly synthesis of pyrazoline derivatives including microwave irradiation, ultrasonic irradiation, grinding and use of ionic liquids which assures the synthesis of the same within much lesser time and by use of minimal energy

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A comparative study using conventional methods, ionic liquids, microwave irradiation and combinations thereof for the synthesis of 5-trifluoroacetyl-1,2,3,4-tetrahydropyridines

Tetrahedron Letters ◽

10.1016/j.tetlet.2018.01.059 ◽

2018 ◽

Vol 59 (10) ◽

pp. 891-894 ◽

Cited By ~ 4

Author(s):

Valquiria P. Andrade ◽

Mateus Mittersteiner ◽

Márcio M. Lobo ◽

Clarissa P. Frizzo ◽

Hélio G. Bonacorso ◽

...

Keyword(s):

Ionic Liquids ◽

Microwave Irradiation ◽

Comparative Study ◽

Conventional Methods

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Ionic Liquids for the Synthesis of Five-Membered N,N-, N,N,N- and N,N,N,NHeterocycles

Current Organic Chemistry ◽

10.2174/1385272823666190717101741 ◽

2019 ◽

Vol 23 (11) ◽

pp. 1214-1238 ◽

Cited By ~ 3

Author(s):

Navjeet Kaur ◽

Pranshu Bhardwaj ◽

Meenu Devi ◽

Yamini Verma ◽

Neha Ahlawat ◽

...

Keyword(s):

Ionic Liquids ◽

Organic Synthesis ◽

Heterocyclic Compounds ◽

Reaction Medium ◽

Environmental Issues ◽

Organic Reaction ◽

Environment Friendly ◽

The Past ◽

Area Of Interest ◽

Major Subject

Due to special properties of ILs (Ionic Liquids) like their wide liquid range, good solvating ability, negligible vapour pressure, non-inflammability, environment friendly medium, high thermal stability, easy recycling and rate promoters etc. they are used in organic synthesis. The investigation for the replacement of organic solvents in organic synthesis is a growing area of interest due to increasing environmental issues. Therefore, ionic liquids have attracted the attention of chemists and act as a catalyst and reaction medium in organic reaction with high activity. There is no doubt that ionic liquids have become a major subject of study for modern chemistry. In comparison to traditional processes the use of ionic liquids resulted in improved, complimentary or alternative selectivities in organic synthesis. The present manuscript reported the synthesis of multiple nitrogen containing five-membered heterocyclic compounds using ionic liquids. This review covered interesting discoveries in the past few years.

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Synthesis, Characterization and Applications of Dicationic Ionic Liquids in Organic Synthesis

Mini-Reviews in Organic Chemistry ◽

10.2174/1570193x16666190508091231 ◽

2020 ◽

Vol 17 (4) ◽

pp. 450-464

Author(s):

Mohammad Javaherian ◽

Seyyed Jafar Saghanezhad

Keyword(s):

Ionic Liquids ◽

Organic Synthesis ◽

Chemical Properties ◽

Physical And Chemical Properties ◽

Dicationic Ionic Liquids ◽

Physical And Chemical ◽

Reaction Media ◽

And Chemical Properties

Dicationic ionic liquids are an emerging group of Ionic Liquids (ILs) that are currently receiving much attention as green reaction media and catalysts. Because of a great number of possible combinations of cations and anions, the physical and chemical properties of dicationic ionic liquids are more tunable and broader than monocationic ILs. Therefore, their unique properties have made them the target of many applied and fundamental researches. Actually, dicationic ionic liquids are more effective and rather fascinating than traditional monocationic ILs. So, due to greater versatility and diversity, their applications in organic synthesis have been extensively grown. In this review, we have focused on the synthesis, characterization and applications of dicationic ionic liquids, especially, in organic synthesis.

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