Synthesis and Characterization of Some 4- Substituted Thiazolidinone Derivatives

2019 ◽  
Vol 10 (04) ◽  
pp. 631-636
Author(s):  
Zainab Ryad Magtoof ◽  
Mahmood Shakir Magtoof
Keyword(s):  
Schiff Bases ◽  
1H Nmr ◽  
13C Nmr ◽  
Mercaptoacetic Acid ◽  
Spectral Studies ◽  
Synthesis And Characterization

This study is concerned with the synthesis and characterization of 4-thiazolidinone derivatives (3a-3e). These compounds were prepared by reacting mercaptoacetic acid with the appropriate Schiff bases (imines) by heating at 50-60 °C in chloroform with moderate yields (51- 75 %). The structures of these 4-thiazolidinone derivatives were established on the basis of spectral studies using IR, 1H-NMR, 13C-NMR, and13C-NMR DEPT .

scholarly journals Synthesis and Characterization of Derivatives Based on 4, - Dimercaptobiphenyl

2012 ◽  
Vol 9 (4) ◽  
pp. 703-712
Author(s):  
Baghdad Science Journal
Keyword(s):  
Schiff Bases ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Synthesis And Characterization

Starting from 4, - Dimercaptobiphenyl, a variety of phenolic Schiff bases (methylolic, etheric, epoxy) derivatives have been synthesized. All proposed structure were supported by FTIR, 1H-NMR, 13C-NMR Elemental analysis all analysis were performed in center of consultation in Jordan Universty.

scholarly journals Synthesis and Characterization of New phenolic Schiff bases Derivatives Based on Terephthaladehyde

2013 ◽  
Vol 10 (3) ◽  
pp. 699-711
Author(s):  
Baghdad Science Journal
Keyword(s):  
Thermal Analysis ◽  
Schiff Bases ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Synthesis And Characterization

A variety of new phenolic Schiff bases derivatives have been synthesized starting from Terephthaladehyde compound, all proposed structures were supported by FTIR, 1H-NMR, 13C-NMR, Elemental analysis, some derivatives evaluated by Thermal analysis (TGA).

Synthesis and Characterization of N-butyl-N-methylimidazolium- D-(-)-tartrate Chiral Ionic Liquid

2012 ◽  
Vol 518-523 ◽  
pp. 3989-3992 ◽  
Author(s):  
Yang Zhang ◽  
Xiao Hua Tu ◽  
Cheng Ping Miao ◽  
Jian Yi Wu
Keyword(s):  
Ionic Liquid ◽  
1H Nmr ◽  
Ion Chromatography ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Optical Rotation ◽  
Synthesis And Characterization ◽  
13C Nmr Spectra ◽  
Chiral Ionic Liquid

A novel CIL of N-butyl-N-methyl imidazolium-D-(-)-tartrate has been designed and synthesized by neutralization reaction. Its structure was characterized by 1H-NMR and 13C-NMR spectra, the optical rotation was characterized by polarimeter with the value of-15.0º, and the purity was characterized by ion chromatography with the value of 98.4%.

scholarly journals Synthesis and characterization of 2,3,13,14-tetramethyl (ethyl or p-tolyl)- 1,4,12,15-tetraazacyclodocosa-1,3,12,14-tetraene complexes of Mg(II), Ca(II), Sr(II) and Ba(II)

2002 ◽  
Vol 67 (7) ◽  
pp. 523-530 ◽  
Author(s):  
Raghu Prasad ◽  
Seema Gupta
Keyword(s):  
1H Nmr ◽  
Elemental Analysis ◽  
Membered Ring ◽  
Spectral Studies ◽  
Synthesis And Characterization

2+2 Cyclocondensation of 1,7-diaminoheptane with ?-diketones, viz 2,3-butanedione, 3,4-hexanedione or 4,4?-dimethylbenzil, in the presence of Mg2+, Ca2+, Sr2+ and Ba2+ ions as templates yields a series of complexes of the type [ML(X2)](where L = N4 macrocycle having a 22-membered ring and X=Cl or NCS). The resulting complexes were characterized by elemental analysis conductance measurements and IR and 1H-NMR spectral studies.

Synthesis and Characterization of (1, 4)-4-benzylidene-1-(1- phenylethylidene) thiosemicarbazide and their Antifungal Activities

10.26524/sa2 ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 08-19
Author(s):  
L Ilavarasan ◽  
A Ravi ◽  
M Ganapathi ◽  
R Sapthagiri ◽  
K Mohanraj ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Schiff Bases ◽  
1H Nmr ◽  
Conventional Method ◽  
Research Work ◽  
Synthesis And Characterization ◽  
Antifungal Activities ◽  
Aryl Aldehydes ◽  
Anti Fungal

The Present research work is aimed to synthesize a serious of various substituted Schiff bases compounds of 1-(1-phenylethylidene)thiosemicarbazide form (1,4)-4-benzylidene-1-(1-phenylethylidene)Thiosemicarbazide condenses with Four different substituted aryl aldehydes under Microwave irradiation and conventional method. The structure for compounds has been determined by UV, FTIR, 1H-NMR and Mass s spectroscopy. All the compounds are evaluated for its anti-fungal activity.

scholarly journals Synthesis and characterization of thiacalix[3]triazine and 1,3,5-tris(4- bromophenyl)benzene for chemsensor application

2018 ◽  
Vol 1 (6) ◽  
pp. 163-176
Author(s):  
Ha Tran Nguyen ◽  
Anh Tuan Luu
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Chemical Structure ◽  
Synthesis And Characterization

The synthesis of thiacalix[3]triazines and 1,3,5- tris(4-bromophenyl)benzene have been synthesized via simple steps and was characterized to determine the chemical structure. The structure of Thiacalix[3]triazines was characterized via 1H NMR and 13C NMR that conformed the expected structure of compound. In addition, the thiacalix[3]triazines exhibited the λmax at 560 nm and λonset at 720 nm which corresponding to the bandgap of 1.7 ev. Thiacalix[3]triazines, cyclotrimeric metacyclophanes with direct S linkages between the heteroaryl constituents, were shown to associate with anion that could be useful for chemsensor application.

scholarly journals Synthesis and Characterization of Five, Sevene Heterocyclic Membered Rings

2013 ◽  
Vol 10 (3) ◽  
pp. 803-817
Author(s):  
Baghdad Science Journal
Keyword(s):  
Biological Activity ◽  
Schiff Bases ◽  
13C Nmr ◽  
Starting Material ◽  
Synthesis And Characterization ◽  
Melting Points ◽  
Vis Spectroscopy ◽  
Ft Ir ◽  
New Compounds

New compounds containing heterocyclic units have been synthesized. These compounds include 2-amino 5- phenyl-1,3,4-thiadiazole (1) as starting material to prepare the Schiff bases 2N[3-nitrobenzylidene -2 hydroxy benzylidene and 4-N,N-dimethyl aminobenzylidene] -5-phenyl-1,3,4-thiadiazole (2abc) , 2N[3-nitrophenyl, 2-hydroxyphenyl or 4-N,N-dimethylaminophenyl] 3-]2-amino-5-phenyl-1,3,4-thiadiazole]-2,3-dihydro-[1,3]oxazepine-benzo-4,7-dione] (3abc), 2N[3-nitrophenyl,2-hydroxyphenyl,4-N,N-dimethylaminophenyl]-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2-yl]-2,3-dihydro-[1,3]oxazepine-4,7-dione[(4abc), 2-N-[3-nitrophenyl, 2-hydroxyphenyl or 4-N,N-dimethylaminophenyl]-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2yl]-1,2,3-trihydro-benzo-[1,2-e][1,3] diazepine-4,7-dione (5abc) ,2N[2-(3-nitrophenyl,2-hydroxyphenyl or 4-N,N-dimethylaminophenyl)]-4-oxo-1,3-thiazolidine-3-yl]-2-amino-5-phenyl-1,3,4-thiadiazole (6abc), 2-N-[5-(3-nitrophenyl,2-hydroxyphenyl or 4-N,N-dimethylaminophenyl)-tetrazolo-1-yl]-2-amino-5-phenyl-1,3,4-thiadiazole (7abc) , 2-N-[5-(3-nitrophenyl,2-hydroxyphenyl or 4-N,N-dimethylaminophenyl)-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2-yl]-2,3-dihydro-[1,3]oxazepine-benzo-4,7-dithione (8abc) , 2-N-[5-(3-nitrophenyl,2-hydroxyphenyl or 4-N,N-dimethylaminophenyl)-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2-yl]-2,3-dihydro-[1,3]oxazepine -4,7-dithione -5-ene (9abc) and 2-N-[5-(3-nitrophenyl,2-hydroxyphenyl or 4-N,N-dimethylaminophenyl)-3-[2-amino-5-phenyl-1,3,4-thiadiazole-2-yl] -1,2,3-trihydro-benzo-[1,2-e][1,3] diazepine -4,7-dithione - (10abc) . the structures of these compounds were characterized by FT-IR, 1H,13C-NMR,Uv/vis spectroscopy and the melting points were determined besides the evaluation of its biological activity.

Synthesis and Characterization of Highly Regioregular Poly (3 - Hexylthiophene)

2011 ◽  
Vol 306-307 ◽  
pp. 1649-1652 ◽  
Author(s):  
C.Y. Zhou ◽  
Lu Ting Yan ◽  
L.N. Zhang ◽  
X.D. Ai ◽  
T.X. Li
Keyword(s):  
Data Analysis ◽  
Absorption Spectra ◽  
1H Nmr ◽  
13C Nmr ◽  
Synthesis And Characterization ◽  
Nmr Data ◽  
Regioregular Poly

Regioregular poly (3-hexylthiophene) was synthesized by exchanging with Grignard agent followed by coupling with catalysis of Ni (dppp)Cl2. A nearly 100% HT-HT structure was verified from 1H-NMR and 13C-NMR data analysis. This highly regioregular structure gives P3HT outstanding stability and certain redshift of absorption spectra was found in contrast to materials with lower regioregularity.

scholarly journals Synthesis and Characterization of 3 - Substituted Coumarin

2016 ◽  
Vol 13 (1) ◽  
pp. 89-96
Author(s):  
Baghdad Science Journal
Keyword(s):  
Acetic Acid ◽  
Schiff Bases ◽  
1H Nmr ◽  
Acetyl Chloride ◽  
Aromatic Aldehydes ◽  
Synthesis And Characterization ◽  
Carbonyl Chloride ◽  
Ft Ir

The reaction of(2-oxo-2H-chromen-3-Carbonyl chloride)(k1) with hydrazine in boiling ethanol gives the hydrazide(K2).When compound (k2) reacts with various aromatic aldehydes ,the corres ponding Schiff bases(k3–k4) achieve new series of thiazotidines (k5–k6) and azetidinones (k7–k8) obtained from the reactions of appropriate Schiff bases with mercapto acetic acid and chloro acetyl chloride respectively. All the compounds are characterized by FT-IR,1H-NMR and GC-Ms.

scholarly journals The synthesis and characterization of some novel 5-chloro-2-(substituted alkoxy)-N-phenylbenzamide derivatives

2009 ◽  
Vol 74 (8-9) ◽  
pp. 847-855 ◽  
Author(s):  
Ioana Ienaşcu ◽  
Alfa Lupea ◽  
Iuliana Popescu ◽  
Mirabela Pădure ◽  
Alina Zamfir
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Methyl Ketone ◽  
Ethyl Esters ◽  
Biologically Active ◽  
Synthesis And Characterization ◽  
Ethyl Methyl ◽  
Elemental Analyses ◽  
Ethyl Methyl Ketone

To obtain biologically active compounds, the synthesis of some new derivatives with an o-hydroxybenzamide structure was performed. The ethyl esters 4-6 were obtained by the reaction of 5-chloro-2-hydroxy-N-phenylbenzamide and chloro-substituted acid ethyl esters 1-3 in ethyl methyl ketone. The obtained ethyl esters were condensed with hydrazine yielding the hydrazides 7-8. The hydrazones 11-14 were obtained by the reaction of the hydrazides and the chloro-substituted benzaldehydes 9-10. All the newly synthesized compounds were characterized by FTIR, 1H-NMR, 13C-NMR, MS and elemental analyses.

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