Regioselective installation of enolizable ketones and unprotected mercaptoacetic acid into olefins using GO as phase transfer catalyst

We report herein unprecedented conjugate addition of enolizable ketones and unprotected mercaptoacetic acid to electron poor alkenes using graphene oxide as phase transfer catalyst. The envisaged protocol is versatile and...

CYANALKYLATION OF MERCAPTOACETIC ACID ESTERS

The addition of mercaptoacetic acid esters (MAAE) to nitriles of acrylic, methacrylic, and crotonic acids easily occurs in the presence of triethylamine as a catalyst to form the corresponding 2-cyanoal-kyl¬alkoxycarbonylmethyl sulfides

Syntheses, Magnetic, Spectral and Biological Studies on the Coordination Compounds of N-(2-Hydroxyphenyl)-C-(3′- Carboxy-2′-Hydroxyphenyl) Thiazolidin-4-One

A dry benzene solution of the Schiff base, N-(2-hydroxyphenyl)-3′-carboxy-2′- hydroxybenzylideneimine upon reacting with mercaptoacetic acid undergoes cyclization and forms N- (2-hydroxyphenyl)-C-(3′-carboxy-2′-hydroxyphenyl)thiazolidin-4-one, LH3 (I). A MeOH solution of I reacts with Ni(II) and UO2(VI) ions and forms the monomeric coordination compounds, [Ni(LH)(MeOH)3] and [UO2(LH)(MeOH)]. The coordination compounds have been characterized on the basis of elemental analyses, molar conductance, molecular weight, spectral (IR, reflectance) studies and magnetic susceptibility measurements. I behaves as a dibasic tridentate OOS donor ligand in these compounds. The compounds are non-electrolytes (M = 4.3-6.4 mho cm2 mol-1) in DMF. Octahedral structure for Ni(II) and UO2(VI) compounds are suggested. LH3 (I) and its complexes while testing with E.Coli. (Gram Negative) and S. Aureus (Gram positive) bacteria show antibacterial activities.

Synthesis, Characterization of Thiazolidin-4-one, Oxazolidin-4-one and Imidazolidin-4-one Derivatives from 6-Amino-1,3-dimethyluracil and evaluation of their Antioxidant and Antimicrobial Agent

In this study, a new series of 6-amino-1,3-dimethyluracil derivative with 6-(3-substituted N-benzylidene)-1,3-dimethyl pyrimidine-2,4-dione-6-yl derivatives which were synthesized by using one pot synthesis. The reaction of 6-amino-1,3-dimethyluracil and different aromatic aldehyde in ethanol yielded Schiff bases (1-6). In the subsequent step reaction of Schiff bases )1-6) with 2-mercaptoacetic acid, 2-chloroacetic acid and 2-amino acetic acidn in Tetrahydrofuran yielded five membered heterocyclic rings of 6-amino-1,3-dimethyluracil derivative which includes: 2,3-thiazolidin-4-one (7-12), 2,3-oxazolidin-5-one (13-18), 2,3-imidazolidin-4-one (19-24) derivatives. The structures of newly synthesized compounds were confirmed by their physicochemical and spectral means FTIR, 1HNMR and 13CNMR. The synthesized compounds were evaluated in vitro for antioxidant and antimicrobial activities against four types of bacteria and four types of fungi

Formation and Application of Core–Shell of FePt-Au Magnetic–Plasmonic Nanoparticles

Monodispersed FePt core and FePt–Au core–shell nanoparticles (NPs) have been chemically synthesized in liquid solution and with controllable surface-functional properties. The NP size was increased from 2.5 nm for FePt to 6.5 nm for FePt–Au, which could be tuned by the initial concentration of gold acetate coated onto FePt seeding NPs via a seed-mediated formation of self-assembled core–shell nanostructures. The analyses of the interplanar spacing obtained from the high-resolution transmission electron microscopy (HRTEM), selective electron diffraction pattern (SAED), and x-ray diffraction (XRD) confirmed that both FePt core and Au shell belong to the face-centered cubic (fcc) structure. FePt–Au NPs have a surface plasmon resonance (SPR) peak at 528 nm in the visible optical band region, indicating the red shift compared with the typical theoretical value of 520 nm of pure Au NPs. The surface modification and ligand exchange of FePt–Au was using mercaptoacetic acid (thiol) as a phase transfer reagent that turned the NPs hydrophilic due to the functional carboxyl group bond on the surface of presented multifunctional magnetic–plasmonic NPs. The water-dispersible FePt-based NPs conjugated with biomolecules could reach the different biocompatibility requirements and also provide enough heating response that acted as a potential agent for magnetic fluid hyperthermia in biomedical engineering research fields.

Acquisition of Optimum Co-sources of Sulfur MAA Capped-ZnS Quantum Dots Conditions for Photoluminescence Chlorine Sensor

ZnS quantum dots (QDs) has received a great attention due to its unique properties and wide applications. The objective of this work is to synthesize ZnS QDs by hydrothermal method and capped with mercaptoacetic acid (MAA) to be used as a chlorine sensor in the range from 1 to 35 mg/L. Optical, structural and morphological properties of MAA capped-ZnS QDs were investigated. MAA capped-ZnS QDs exhibited a cubic structure with an average diameter size of 8.8 nm. Photoluminescence (PL) spectra of the fabricated MAA capped-ZnS QDs revealed three basic emission peaks at 371, 423 and 486 nm due to level transitions involving of zinc vacancy, interstitial sulfur and zinc, respectively. The photostability of the MAA capped-ZnS QDs was examined after 14 months which retains 12% of the original PL intensity without any peak shift. The MAA capped-ZnS QDs PL intensity was changed linearly with the chlorine concentration in the range from 1 to 35 mg/L with correlation coefficient, sensitivity and limit of detection of 0.9782, 6.96×10-2 ppm-1 and 3.6 mg/L, respectively.

Selective Colorimetric Sensing of Deferoxamine with 4-Mercaptophenol− and Mercaptoacetic acid−Functionalized Gold Nanoparticles via Fe(III)-Chelation

A gold nanoparticle-based colorimetric probe was developed for the determination of deferoxamine (desferrioxamine, DFO), a strong Fe(III) ion-chelator. Au-nanoparticles were synthesized and modified with 4-mercaptophenol (4MP) and mercaptoacetic acid (MAA)...