Interrelationships Between Sex and Exogenous Growth Hormone Administration on Performance, Body Composition and Protein and Fat Accretion of Growing Pigs

1989 ◽  
Vol 67 (1) ◽  
pp. 177 ◽  
Author(s):  
R. G. Campbell ◽  
N. C. Steele ◽  
T. J. Caperna ◽  
J. P. McMurtry ◽  
M. B. Solomon ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Growing Pigs ◽  
Growth Hormone Administration ◽  
Hormone Administration ◽  
Exogenous Growth ◽  
Fat Accretion

Effects of ovariectomy and growth hormone administration on body composition and vascular function and structure in old female rats

2005 ◽  
Vol 6 (1) ◽  
pp. 49-60 ◽  
Author(s):  
C. Castillo ◽  
M. Cruzado C. Ariznavarreta ◽  
V. Lahera ◽  
V. Cachofeiro ◽  
P. Gil-Loyzaga ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Vascular Function ◽  
Female Rats ◽  
Growth Hormone Administration ◽  
Hormone Administration

Effect of exogenous growth hormone administration on endogenous growth hormone secretion induced by a met-enkephalin analog

1996 ◽  
Vol 134 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Giuseppe Fanciulli ◽  
Osvaldo Oliva ◽  
Paolo A Tomasi ◽  
Alessandra Pala ◽  
Alba Bertoncelli ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Endogenous Growth ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Inhibitory Effect ◽  
Growth Hormone Administration ◽  
Gh Secretion ◽  
Hormone Administration ◽  
Exogenous Growth ◽  
Serum Gh

Fanciulli G, Oliva O, Tomasi PA. Pala A. Bertoncelli A, Dettori A, Delitala G. Effect of exogenous growth hormone administration on endogenous growth hormone secretion induced by a met-enkephalin analog. Eur J Endocrinol 1996:134:73–6. ISSN 0804–4643 Exogenous growth hormone (hGH) administration in humans attenuates the endogenous growth hormone (GH) response to some pharmacological stimuli: in particular, pretreatment with hGH completely blocks the serum GH response to growth hormone-releasing hormone. In order to evaluate the mechanism(s) whereby opioids induce GH secretion in man, we gave the following treatments to six healthy male volunteers: (a) IV saline: (b) a met-enkephalin analog G-DAMME 250 μg IV as a bolus at time ′: (c) hGH 2 IU as an IV bolus at time −180′; (d) G-DAMME as above, preceded by hGH as above. In our study. G-DAMME stimulated GH secretion both basally (peak 17.9 ± 6.0 ng/ml) and, to a lesser extent, after hGH pretreatment (6.0 ± 2.7 ng/ml). Since in our study G-DAMME was able to partially overcome the inhibitory effect of hGH administration, it is suggested that opioids act through an inhibition of somatostatin release and not through a GHRH-dependent pathway. However, an additional direct effect of hGH on pituitary somatotrophes cannot be excluded. Giuseppe Delitala, Chair of Endocrinology, Viale S. Pietro 12, University of Sassari, 07100 Sassari. Italy

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