This paper focuses to design a compact (110mm³) Ultra-Wide Band (UWB) (3.1GHz to 10.6GHz) antenna, which covers almost the whole 10dB impedance matching bandwidth of the UWB range. Two of the main specialties of this article over other related articles are its antenna’s wider bandwidth (approx. 7.3GHz) and antenna’s simulation environment. No other papers consider such a realistic model to simulate their antenna, before. Due to its wider bandwidth, this antenna can be employed in the Wireless Capsule Endoscopy (WCE) system, which mainly requires a high-speed real-time data transfer-capable antenna. The antenna was examined inside simplified human Gastrointestinal (GI) tract phantoms (Colon, Esophagus, Small Intestine and Stomach) as well as the human Voxel GI tract model by maintaining proper tissue properties for the sake of accurate parametric results. Biocompatible material polyimide was used to construct the capsule wall to fulfill the system’s biocompatibility. In the result analysis part, the proposed antenna’s SAR (Specific Absorption Rate) or electromagnetic energy amount, consumed by near-side body tissue was considered and found in the acceptable region, according to Federal Communication Commission (FCC)’s regulation. Also, other crucial antenna parameters such as VSWR, reflection coefficient, radiation characteristics, efficiencies, directivity and surface current density were adoptable compare to other related articles. The Finite Integration Technique (FIT) of CST Microwave Studio Suite 2020 was used to investigate the antenna parameters.