The Role of Light Anhydrous Silicic Acid on Physical Stability of Troglitazone Solid Dispersion

2016 ◽  
Author(s):  
Toshiyuki Nakahashi
Keyword(s):  
Silicic Acid ◽  
Solid Dispersion ◽  
Physical Stability ◽  
Role Of Light

The role of light anhydrous silicic acid on physical stability of troglitazone solid dispersion under humidified conditions

2014 ◽  
Vol 25 (2) ◽  
pp. 716-721 ◽  
Author(s):  
Toshiyuki Nakahashi ◽  
Takahiro Matsumoto ◽  
Naoki Wakiyama ◽  
Kunikazu Moribe ◽  
Keiji Yamamoto
Keyword(s):  
Silicic Acid ◽  
Solid Dispersion ◽  
Physical Stability ◽  
Role Of Light

Characteristics Of The Structure Formation Of Gypsum Binder Modified With Zinc Hydrosilicates

2020 ◽  
pp. 40-46
Keyword(s):  
Synergistic Effect ◽  
Physicochemical Properties ◽  
Structure Formation ◽  
Silicic Acid ◽  
Chemical Properties ◽  
Crystal Formation ◽  
Ability To Act ◽  
Chemical Factors ◽  
Sorption Characteristics

The authors' methodic for assessing the role of chemical and physic-chemical factors during the structure formation of gypsum stone is presented in the article. The methodic is also makes it possible to reveal the synergistic effect and to determine the ranges of variation of controls factors that ensure maximum values of such effect. The effect of a micro-sized modifier based on zinc hydro-silicates on the structure formation of building gypsum is analyzed and corresponding dependencies are found. It is shown that effects of influence of modifier on the properties of gypsum compositions are determined by chemical properties of modifier. Among the mentioned properties are sorption characteristics (which depend on the amount of silicic acid and its state) and physicochemical properties - the ability to act as a substrate during crystal formation. The proposed method can also be extended to other binding substances and materials. This article contributes to the understanding of the processes that occur during the structure formation of composites, which will make it possible to control the structure formation in the future, obtaining materials with a given set of properties.

scholarly journals Assessing the Role of Light Absorption in Laser Lithotripsy by Isotopic Substitution of Kidney Stone Materials

2020 ◽  
Vol 6 (9) ◽  
pp. 5274-5280
Author(s):  
Sorout Shalini ◽  
Derek S. Frank ◽  
Ali H. Aldoukhi ◽  
Sami E. Majdalany ◽  
William W. Roberts ◽  
...  
Keyword(s):  
Light Absorption ◽  
Kidney Stone ◽  
Laser Lithotripsy ◽  
Isotopic Substitution ◽  
Stone Materials ◽  
Role Of Light

Role of Light and Medium Composition on Growth and Valepotriate Contents in Valeriana glechomifolia Whole Plant Liquid Cultures

2006 ◽  
Vol 86 (2) ◽  
pp. 211-218 ◽  
Author(s):  
Denise Russowski ◽  
Natasha Maurmann ◽  
Sandra Beatriz Rech ◽  
Arthur Germano Fett-Neto
Keyword(s):  
Medium Composition ◽  
Liquid Cultures ◽  
Whole Plant ◽  
Role Of Light

Role of light-induced scattering in the optical limitation of laser radiation on the basis of fullerene-containing media

2001 ◽  
Vol 90 (2) ◽  
pp. 292-301 ◽  
Author(s):  
I. M. Belousova ◽  
V. A. Grigor’ev ◽  
O. B. Danilov ◽  
A. G. Kalintsev ◽  
A. V. Kris’ko ◽  
...  
Keyword(s):  
Laser Radiation ◽  
Optical Limitation ◽  
Role Of Light

scholarly journals Influence of Drug Load on the Printability and Solid-State Properties of 3D-Printed Naproxen-Based Amorphous Solid Dispersion

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4492
Author(s):  
Eric Ofosu Kissi ◽  
Robin Nilsson ◽  
Liebert Parreiras Nogueira ◽  
Anette Larsson ◽  
Ingunn Tho
Keyword(s):  
Solid State ◽  
3D Printing ◽  
Solid Dispersion ◽  
Physical Stability ◽  
Amorphous Solid ◽  
Amorphous Solid Dispersion ◽  
Drug Load ◽  
X Ray ◽  
3D Printed ◽  
Hot Melt

Fused deposition modelling-based 3D printing of pharmaceutical products is facing challenges like brittleness and printability of the drug-loaded hot-melt extruded filament feedstock and stabilization of the solid-state form of the drug in the final product. The aim of this study was to investigate the influence of the drug load on printability and physical stability. The poor glass former naproxen (NAP) was hot-melt extruded with Kollidon® VA 64 at 10–30% w/w drug load. The extrudates (filaments) were characterised using differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), and thermogravimetric analysis (TGA). It was confirmed that an amorphous solid dispersion was formed. A temperature profile was developed based on the results from TGA, DSC, and DMA and temperatures used for 3D printing were selected from the profile. The 3D-printed tablets were characterised using DSC, X-ray computer microtomography (XµCT), and X-ray powder diffraction (XRPD). From the DSC and XRPD analysis, it was found that the drug in the 3D-printed tablets (20 and 30% NAP) was amorphous and remained amorphous after 23 weeks of storage (room temperature (RT), 37% relative humidity (RH)). This shows that adjusting the drug ratio can modulate the brittleness and improve printability without compromising the physical stability of the amorphous solid dispersion.

The role of light intensity in mediating ascorbic acid content during postharvest tomato ripening: A transcriptomic analysis

2021 ◽  
Vol 180 ◽  
pp. 111622
Author(s):  
Yating Zhang ◽  
Nikolaos Ntagkas ◽  
Dimitrios Fanourakis ◽  
Georgios Tsaniklidis ◽  
Jiantao Zhao ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Light Intensity ◽  
Acid Content ◽  
Ascorbic Acid Content ◽  
Transcriptomic Analysis ◽  
Role Of Light
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