Association between mindfulness, social cognition, and social functioning: an exploratory and proof-of-concept analysis

Abstract Objective To characterize social cognition, language, and social behavior as potentially shared vulnerability markers in children at familial high-risk of schizophrenia (FHR-SZ) and bipolar disorder (FHR-BP). Methods The Danish High-Risk and Resilience Study VIA7 is a multisite population-based cohort of 522 7-year-old children extracted from the Danish registries. The population-based controls were matched to the FHR-SZ children on age, sex, and municipality. The FHR-BP group followed same inclusion criteria. Data were collected blinded to familial high-risk status. Outcomes were social cognition, language, and social behavior. Results The analysis included 202 FHR-SZ children (girls: 46%), 120 FHR-BP children (girls: 46.7%), and 200 controls (girls: 46.5%). FHR-SZ children displayed significant deficits in language (receptive: d = −0.27, P = .006; pragmatic: d = −0.51, P < .001), social responsiveness (d = −0.54, P < .001), and adaptive social functioning (d = −0.47, P < .001) compared to controls after Bonferroni correction. Compared to FHR-BP children, FHR-SZ children performed significantly poorer on adaptive social functioning (d = −0.29, P = .007) after Bonferroni correction. FHR-BP and FHR-SZ children showed no significant social cognitive impairments compared to controls after Bonferroni correction. Conclusion Language, social responsiveness, and adaptive social functioning deficits seem associated with FHR-SZ but not FHR-BP in this developmental phase. The pattern of results suggests adaptive social functioning impairments may not be shared between FHR-BP and FHR-SZ in this developmental phase and thus not reflective of the shared risk factors for schizophrenia and bipolar disorder.

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Social predictors of psychotic experiences in adolescence: the role of social cognition, social functioning, parenting and religiosity in the emergence and course of adolescent psychotic experiences

10.33612/diss.95011080 ◽

2019 ◽

Author(s):

Laura Alida Steenhuis

Keyword(s):

Social Cognition ◽

Social Functioning ◽

Psychotic Experiences ◽

Social Predictors

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Perfluoroalkyl substances, metabolomic profiling, and alterations in glucose homeostasis among overweight and obese Hispanic children: A proof-of-concept analysis

Environment International ◽

10.1016/j.envint.2019.02.047 ◽

2019 ◽

Vol 126 ◽

pp. 445-453 ◽

Cited By ~ 23

Author(s):

Tanya L. Alderete ◽

Ran Jin ◽

Douglas I. Walker ◽

Damaskini Valvi ◽

Zhanghua Chen ◽

...

Keyword(s):

Glucose Homeostasis ◽

Concept Analysis ◽

Perfluoroalkyl Substances ◽

Proof Of Concept ◽

Hispanic Children ◽

Metabolomic Profiling

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Dynamic Interactive Social Cognition Training in Virtual Reality (DiSCoVR) for social cognition and social functioning in people with a psychotic disorder: study protocol for a multicenter randomized controlled trial

BMC Psychiatry ◽

10.1186/s12888-019-2250-0 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 6

Author(s):

Saskia A. Nijman ◽

Wim Veling ◽

Kirstin Greaves-Lord ◽

Rowina R. Vermeer ◽

Maarten Vos ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Virtual Reality ◽

Social Cognition ◽

Social Functioning ◽

Psychotic Disorder ◽

Study Protocol ◽

Controlled Trial ◽

Randomized Controlled ◽

Multicenter Randomized Controlled Trial ◽

Social Cognition Training

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The role of social relatedness and self-beliefs in social functioning in first-episode psychosis: Are we overestimating the contribution of illness-related factors?

European Psychiatry ◽

10.1192/j.eurpsy.2020.90 ◽

2020 ◽

Vol 63 (1) ◽

Author(s):

César González-Blanch ◽

Leonardo A. Medrano ◽

Sarah Bendall ◽

Simon D’Alfonso ◽

Daniela Cagliarini ◽

...

Keyword(s):

Social Cognition ◽

Social Functioning ◽

Negative Symptoms ◽

First Episode Psychosis ◽

Equation Modeling ◽

First Episode ◽

Related Factors ◽

Social Relatedness ◽

Episode Psychosis ◽

Fit Index

Abstract Objective Numerous research studies have demonstrated an association between higher symptom severity and cognitive impairment with poorer social functioning in first-episode psychosis (FEP). By contrast, the influence of subjective experiences, such as social relatedness and self-beliefs, has received less attention. Consequently, a cohesive understanding of how these variables interact to influence social functioning is lacking. Method We used structural equation modeling to examine the direct and indirect relationships among neurocognition (processing speed) and social cognition, symptoms, and social relatedness (perceived social support and loneliness) and self-beliefs (self-efficacy and self-esteem) in 170 individuals with FEP. Results The final model yielded an acceptable model fit (χ2 = 45.48, comparative fit index = 0.96; goodness of fit index = 0.94; Tucker–Lewis index = 0.94; root mean square error of approximation = 0.06) and explained 45% of social functioning. Negative symptoms, social relatedness, and self-beliefs exerted a direct effect on social functioning. Social relatedness partially mediated the impact of social cognition and negative symptoms on social functioning. Self-beliefs also mediated the relationship between social relatedness and social functioning. Conclusions The observed associations highlight the potential value of targeting social relatedness and self-beliefs to improve functional outcomes in FEP. Explanatory models of social functioning in FEP not accounting for social relatedness and self-beliefs might be overestimating the effect of the illness-related factors.

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